Søren Gøgsig Faarup Rasmussen

Søren Gøgsig Faarup Rasmussen

Associate Professor

ORCID: 0000-0002-1853-1841

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  1. Published

    Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6

    Ballesteros, J. A., Jensen, A. D., Liapakis, G., Rasmussen, Søren Gøgsig Faarup, Shi, L. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (31), p. 29171-29177

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

    Bokoch, M. P., Zou, Y., Rasmussen, Søren Gøgsig Faarup, Liu, C. W., Nygaard, R., Rosenbaum, D. M., Fung, J. J., Choi, H., Thian, F. S., Kobilka, T. S., Puglisi, J. D., Weis, W. I., Pardo, L., Prosser, R. S., Mueller, L. & Kobilka, B. K., 7 Jan 2010, In: Nature. 463, 7277, p. 108-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor

    Boyhus, L. E., Danielsen, Mia, Bengtson, N. S., Kunze, M. B. A., Kubiak, X., Sminia, T. J., Løper, J. H., Tran, P. T., Lindorff-Larsen, Kresten, Rasmussen, Søren Gøgsig Faarup, Mathiesen, Jesper M. & Pedersen, D. S., 2018, In: RSC Advances. 8, 4, p. 2219-2228 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Novel Tripod Amphiphiles for Membrane Protein Analysis

    Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Correction to "tandem facial amphiphiles for membrane protein stabilization"

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In: Journal of the American Chemical Society. 135, 34, p. 12922 1 p.

    Research output: Contribution to journal › Journal article › Research

  7. Published

    Tandem Facial Amphiphiles for Membrane Protein Stabilization

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Chandra, R., Goren, M. A., Kruse, A. C., Nurva, S., Loland, Claus Juul, Pierre, Y., Drew, D., Popot, J., Picot, D., Fox, B. G., Guan, L., Gether, Ulrik, Byrne, B., Kobilka, B. & Gellman, S. H., 2010, In: Nature Methods. 7, p. 1003-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

    Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In: Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In: Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

    Cherezov, V., Rosenbaum, D. M., Hanson, M. A., Rasmussen, Søren Gøgsig Faarup, Thian, F. S., Kobilka, T. S., Choi, H., Kuhn, P., Weis, W. I., Kobilka, B. K. & Stevens, R. C., 23 Nov 2007, In: Science (New York, N.Y.). 318, 5854, p. 1258-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

    Chung, K. Y., Rasmussen, Søren Gøgsig Faarup, Liu, T., Li, S., DeVree, B. T., Chae, P. S., Calinski, D., Kobilka, B. K., Woods, V. L. & Sunahara, R. K., 29 Sep 2011, In: Nature. 477, 7366, p. 611-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Ligand modulation of sidechain dynamics in a wild-type human GPCR

    Clark, L. D., Dikiy, I., Chapman, K., Rodstrom, K. E. J., Aramini, J., LeVine, M. V., Khelashvili, G., Rasmussen, Søren Gøgsig Faarup, Gardner, K. H. & Rosebaum, D. M., Oct 2017, In: eLife. 6, 27 p., e28505.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A monoclonal antibody for G protein-coupled receptor crystallography

    Day, P. W., Rasmussen, Søren Gøgsig Faarup, Parnot, C., Fung, J. J., Masood, A., Kobilka, T. S., Yao, X., Choi, H., Weis, W. I., Rohrer, D. K. & Kobilka, B. K., Nov 2007, In: Nature Methods. 4, 11, p. 927-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

    DeVree, B. T., Mahoney, J. P., Vélez-Ruiz, G. A., Rasmussen, Søren Gøgsig Faarup, Kuszak, A. J., Edwald, E., Fung, J., Manglik, A., Masureel, M., Du, Y., Matt, R. A., Pardon, E., Steyaert, J., Kobilka, B. K. & Sunahara, R. K., 2016, In: Nature. 535, p. 182-6

    Research output: Contribution to journal › Letter › Research › peer-review

  16. Published

    Assembly of a GPCR-G Protein Complex

    Du, Y., Duc, N. M., Rasmussen, Søren Gøgsig Faarup, Hilger, D., Kubiak, X., Wang, L., Bohon, J., Kim, H. R., Wegrecki, M., Asuru, A., Jeong, K. M., Lee, J., Chance, M. R., Lodowski, D. T., Kobilka, B. K. & Chung, K. Y., 2019, In: Cell. 177, 5, p. 1232-1242

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs

    Eriksen, J., Rasmussen, Søren Gøgsig Faarup, Jørgensen, T. N., Vaegter, C. B., Cha, J. H., Zou, M., Newman, A. H. & Gether, Ulrik, 2009, In: Journal of Neuroscience. 29, 21, p. 6794-808 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Structural basis for activation of G-protein-coupled receptors.

    Gether, Ulrik, Asmar, F., Meinild, A. K. & Rasmussen, Søren Gøgsig Faarup, 2002, In: Basic & Clinical Pharmacology & Toxicology. 91, 6, p. 304-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Conformational biosensors reveal GPCR signalling from endosomes

    Irannejad, R., Tomshine, J. C., Tomshine, J. R., Chevalier, M., Mahoney, J. P., Steyaert, J., Rasmussen, Søren Gøgsig Faarup, Sunahara, R. K., El-Samad, H., Huang, B. & von Zastrow, M., 28 Mar 2013, In: Nature. 495, 7442, p. 534-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

    Jensen, A. D., Guarnieri, F., Rasmussen, Søren Gøgsig Faarup, Asmar, F., Ballesteros, J. A. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (12), p. 9279-9290

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Functional studies of isolated GPCR-G protein complexes in the membrane bilayer of lipoprotein particles

    Kuszak, A. J., Yao, X. J., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. & Sunahara, R. K., Dec 2010, G Protein-Coupled Receptors . Cambridge University Press, p. 32-52

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  22. Published

    Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

    Mathiasen, Signe, Christensen, S. M., Fung, J. J., Rasmussen, Søren Gøgsig Faarup, Fay, J. F., Jørgensen, S. K., Veshaguri, S., Farrens, D. L., Kiskowski, M., Kobilka, B. & Stamou, Dimitrios, 2014, In: Nature Methods. 11, p. 931-934 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Yeast surface display platform for rapid discovery of conformationally selective nanobodies

    McMahon, C., Baier, A. S., Pascolutti, R., Wegrecki, M., Zheng, S., Ong, J. X., Erlandson, S. C., Hilger, D., Rasmussen, Søren Gøgsig Faarup, Ring, A. M., Manglik, A. & Kruse, A. C., 2018, In: Nature Structural and Molecular Biology. 25, 3, p. 289-296 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Substrate-Induced Conformational Dynamics of the Dopamine Transporter

    Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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