Research Groups
We currently have 21 research groups:
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The group explores the rise and fall of human consciousness as functions of brain energy metabolism and neurotransmission during development, aging, and neurodegeneration.
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In NerveLab we explore axon degeneration, regeneration, and ion-channel properties in humans and experimental animal models with hereditary peripheral neuropathy using in vivo electrophysiology to study axonal excitability and in animals confirmed by in vivo confocal endomicroscopy.
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Using normal and transgenic models to understand both normal motor function and dysfunction following injury or disease.
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The research focuses on structure-function relationship in neurotransmitter transporters. Specifically, how binding of ions and substrate couple to an allosteric interactions network within the transporter, leading to the translocation of the ligand into the cell.
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The Lab is aiming to develop viral vector-mediated gene therapeutic techniques as novel treatments for CNS disorders.
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The lab's research focuses on human gait by use of biomechanical movement analysis combined with neurophysiological methods like the Hoffmann reflex
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The focus of our interest is the molecular mechanism of neurotransmitter release in central neurons and in neurosecretory cells.
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We are studying how the physiology of neurons and astrocytes contribute to brain functions.
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The overall research interest of the group is to understand how the human brain and spinal cord initiate, plan, execute and optimize movements.
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Research in the group is directed towards understanding how neurons in small assemblies interact to produce sensory and motor functions in the brain.
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We use patch clamp recordings and 2 photon Ca imaging to investigate signaling in dendrites during functional network activity.
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The research addresses fundamental aspects of basic pharmacology, molecular pharmacology and neuropharmacology.
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Martin Fredensborg Rath
We investigate cellular localization, development, regulation and function of circadian rhythm generating centers in the brain
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We use a combination of techniques to study neuroenergetics: electrophysiological techniques to record spike activity from single cells and local field potentials.
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Our focus is to elucidate the molecular mechanisms underlying water and ion homeo-stasis in the mammalian brain under both physiological and pathophysiological conditions.
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Our lab addresses the organization of neuronal networks that are linked to the ability to produce movements, the origin of most behaviors.
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We study the molecular mechanisms of cell communication in the nervous system, using the fruit fly Drosophila melanogaster as our primary experimental system.
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Our scientific problem is to understand how the dynamics of the communications by spiking and resulting membrane conductances drives the populations of neurons in the visual areas to reconstruct the visual scene or interpret sounds and sound sequences.
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Our research takes a system-approach to understanding the central nervous system, with particular emphasis on motor control and the generation of movements.
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The research of the lab is focused on understanding the structural basis for the functional properties of G-protein coupled receptors (GPCRs) and neurotransmitter transporters.
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The overall purpose of our research is to achieve insight into molecular, cellular and genetic processes responsible for synaptic signal transmission and how these processes can be modulated by drugs.
