Søren Gøgsig Faarup Rasmussen
Associate Professor
Neuropharm and Genetics
Blegdamsvej 3
2200 København N.
- Published
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
McMahon, C., Baier, A. S., Pascolutti, R., Wegrecki, M., Zheng, S., Ong, J. X., Erlandson, S. C., Hilger, D., Rasmussen, Søren Gøgsig Faarup, Ring, A. M., Manglik, A. & Kruse, A. C., 2018, In: Nature Structural and Molecular Biology. 25, 3, p. 289-296 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs
Eriksen, J., Rasmussen, Søren Gøgsig Faarup, Jørgensen, T. N., Vaegter, C. B., Cha, J. H., Zou, M., Newman, A. H. & Gether, Ulrik, 2009, In: Journal of Neuroscience. 29, 21, p. 6794-808 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding G-protein coupled receptors and their role in the CNS
Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
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The two-domain elevator-type mechanism of zinc-transporting ZIP proteins
Wiuf, A., Steffen, Jonas Hyld, Becares, E. R., Gronberg, C., Mahato, D. R., Rasmussen, Søren Gøgsig Faarup, Andersson, M., Croll, T., Gotfryd, K. & Gourdon, Pontus Emanuel, 2022, In: Science Advances. 8, 28, 13 p., 4331.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure and function of G-protein-coupled receptors
Rosenbaum, D. M., Rasmussen, Søren Gøgsig Faarup & Kobilka, B. K., 21 May 2009, In: Nature. 459, 7245, p. 356-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of pH on ß2 adrenoceptor function
Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik & Kobilka, B. K., 2000, In: Journal of Biological Chemistry. 5, Vol. 275, p. 3121-3127Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
Yao, X. J., Vélez Ruiz, G., Whorton, M. R., Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Deupi, X., Sunahara, R. K. & Kobilka, B., 9 Jun 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 23, p. 9501-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The beta2 Adrenergic Receptor as a Model for G Protein-Coupled Receptor Structure and Activation by Diffusible Hormones
Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & Kobilka, B., Sep 2009, Handbook of Cell Signaling. Elsevier EditoraResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Tandem Facial Amphiphiles for Membrane Protein Stabilization
Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate-induced conformational dynamics of the dopamine transporter
Nielsen, A. K., Möller, I. R., Wang, Y., Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate-Induced Conformational Dynamics of the Dopamine Transporter
Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor
Rasmussen, Søren Gøgsig Faarup, Choi, H., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 175-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and function of an irreversible agonist-β(2) adrenoceptor complex
Rosenbaum, D. M., Zhang, C., Lyons, J. A., Holl, R., Aragao, D., Arlow, D. H., Rasmussen, Søren Gøgsig Faarup, Choi, H., Devree, B. T., Sunahara, R. K., Chae, P. S., Gellman, S. H., Dror, R. O., Shaw, D. E., Weis, W. I., Caffrey, M., Gmeiner, P. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 236-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex
Westfield, G. H., Rasmussen, Søren Gøgsig Faarup, Su, M., Dutta, S., DeVree, B. T., Chung, K. Y., Calinski, D., Velez-Ruiz, G., Oleskie, A. N., Pardon, E., Chae, P. S., Liu, T., Li, S., Woods, V. L., Steyaert, J., Kobilka, B. K., Sunahara, R. K. & Skiniotis, G., 20 Sep 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 16086-91 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural basis for activation of G-protein-coupled receptors.
Gether, Ulrik, Asmar, F., Meinild, A. K. & Rasmussen, Søren Gøgsig Faarup, 2002, In: Basic & Clinical Pharmacology & Toxicology. 91, 6, p. 304-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy
Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs
Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4
Richter, W., Day, P., Agrawal, R., Bruss, M. D., Granier, S., Wang, Y. L., Rasmussen, Søren Gøgsig Faarup, Horner, K., Wang, P., Lei, T., Patterson, A. J., Kobilka, B. & Conti, M., 23 Jan 2008, In: E M B O Journal. 27, 2, p. 384-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter
Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies
Staus, D. P., Wingler, L. M., Strachan, R. T., Rasmussen, Søren Gøgsig Faarup, Pardon, E., Ahn, S., Steyaert, J., Kobilka, B. K. & Lefkowitz, R. J., Mar 2014, In: Molecular Pharmacology. 85, 3, p. 472-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and fluorescent labeling of the human serotonin transporter
Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In: Biochemistry. 44, 9, p. 3494-505 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing Activation and Conformational Dynamics of the Vesicle-Reconstituted β2 Adrenergic Receptor at the Single-Molecule Level
Tutkus, M., Lundgaard, C. V., Veshaguri, S., Tønnesen, A., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2024, In: Journal of Physical Chemistry B. 128, 9, p. 2124–2133 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel Tripod Amphiphiles for Membrane Protein Analysis
Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46Research output: Contribution to journal › Journal article › Research › peer-review
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Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes
Mathiasen, Signe, Christensen, S. M., Fung, J. J., Rasmussen, Søren Gøgsig Faarup, Fay, J. F., Jørgensen, S. K., Veshaguri, S., Farrens, D. L., Kiskowski, M., Kobilka, B. & Stamou, Dimitrios, 2014, In: Nature Methods. 11, p. 931-934 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI
Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In: Molecular Pharmacology. 56, p. 175-184Research output: Contribution to journal › Journal article › Research › peer-review
ID: 7932
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Ligand modulation of sidechain dynamics in a wild-type human GPCR
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Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor
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Substrate-induced conformational dynamics of the dopamine transporter
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