Søren Gøgsig Faarup Rasmussen

Søren Gøgsig Faarup Rasmussen

Associate Professor


  1. 2010
  2. Published

    Functional studies of isolated GPCR-G protein complexes in the membrane bilayer of lipoprotein particles

    Kuszak, A. J., Yao, X. J., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. & Sunahara, R. K., Dec 2010, G Protein-Coupled Receptors . Cambridge University Press, p. 32-52

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  3. Published

    Tandem Facial Amphiphiles for Membrane Protein Stabilization

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2011
  5. Published

    Structure and function of an irreversible agonist-β(2) adrenoceptor complex

    Rosenbaum, D. M., Zhang, C., Lyons, J. A., Holl, R., Aragao, D., Arlow, D. H., Rasmussen, Søren Gøgsig Faarup, Choi, H., Devree, B. T., Sunahara, R. K., Chae, P. S., Gellman, S. H., Dror, R. O., Shaw, D. E., Weis, W. I., Caffrey, M., Gmeiner, P. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 236-40 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

    Rasmussen, Søren Gøgsig Faarup, Choi, H., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 175-80 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum

    Selao, T. T., Branca, R., Chae, P. S., Lehtiö, J., Gellman, S. H., Rasmussen, Søren Gøgsig Faarup, Nordlund, S. & Norén, A., 3 Jun 2011, In: Journal of Proteome Research. 10, 6, p. 2703-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex

    Westfield, G. H., Rasmussen, Søren Gøgsig Faarup, Su, M., Dutta, S., DeVree, B. T., Chung, K. Y., Calinski, D., Velez-Ruiz, G., Oleskie, A. N., Pardon, E., Chae, P. S., Liu, T., Li, S., Woods, V. L., Steyaert, J., Kobilka, B. K., Sunahara, R. K. & Skiniotis, G., 20 Sep 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 16086-91 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

    Chung, K. Y., Rasmussen, Søren Gøgsig Faarup, Liu, T., Li, S., DeVree, B. T., Chae, P. S., Calinski, D., Kobilka, B. K., Woods, V. L. & Sunahara, R. K., 29 Sep 2011, In: Nature. 477, 7366, p. 611-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Crystal structure of the β2 adrenergic receptor-Gs protein complex

    Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, Jesper M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K., 29 Sep 2011, In: Nature. 477, 7366, p. 549-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2012
  12. Published

    A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In: Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor

    Zocher, M., Zhang, C., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. K. & Müller, D. J., 11 Dec 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 50, p. E3463–E3472

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2013
  15. Published

    Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level

    Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

    Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In: Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Conformational biosensors reveal GPCR signalling from endosomes

    Irannejad, R., Tomshine, J. C., Tomshine, J. R., Chevalier, M., Mahoney, J. P., Steyaert, J., Rasmussen, Søren Gøgsig Faarup, Sunahara, R. K., El-Samad, H., Huang, B. & von Zastrow, M., 28 Mar 2013, In: Nature. 495, 7442, p. 534-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Correction to "tandem facial amphiphiles for membrane protein stabilization"

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In: Journal of the American Chemical Society. 135, 34, p. 12922 1 p.

    Research output: Contribution to journalJournal articleResearch

  19. Published

    Novel Tripod Amphiphiles for Membrane Protein Analysis

    Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2014
  21. Published

    Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

    Mathiasen, Signe, Christensen, S. M., Fung, J. J., Rasmussen, Søren Gøgsig Faarup, Fay, J. F., Jørgensen, S. K., Veshaguri, S., Farrens, D. L., Kiskowski, M., Kobilka, B. & Stamou, Dimitrios, 2014, In: Nature Methods. 11, p. 931-934 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A general protocol for the generation of Nanobodies for structural biology

    Pardon, E., Laeremans, T., Triest, S., Rasmussen, Søren Gøgsig Faarup, Wohlkönig, A., Ruf, A., Muyldermans, S., Hol, W. G. J., Kobilka, B. K. & Steyaert, J., Mar 2014, In: Nature Protocols (Print). 9, 3, p. 674-93 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies

    Staus, D. P., Wingler, L. M., Strachan, R. T., Rasmussen, Søren Gøgsig Faarup, Pardon, E., Ahn, S., Steyaert, J., Kobilka, B. K. & Lefkowitz, R. J., Mar 2014, In: Molecular Pharmacology. 85, 3, p. 472-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2016
  25. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

    DeVree, B. T., Mahoney, J. P., Vélez-Ruiz, G. A., Rasmussen, Søren Gøgsig Faarup, Kuszak, A. J., Edwald, E., Fung, J., Manglik, A., Masureel, M., Du, Y., Matt, R. A., Pardon, E., Steyaert, J., Kobilka, B. K. & Sunahara, R. K., 2016, In: Nature. 535, p. 182-6

    Research output: Contribution to journalLetterResearchpeer-review

  26. 2017
  27. Published

    Ligand modulation of sidechain dynamics in a wild-type human GPCR

    Clark, L. D., Dikiy, I., Chapman, K., Rodstrom, K. E. J., Aramini, J., LeVine, M. V., Khelashvili, G., Rasmussen, Søren Gøgsig Faarup, Gardner, K. H. & Rosebaum, D. M., Oct 2017, In: eLife. 6, 27 p., e28505.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2018
  29. Published

    Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor

    Boyhus, L. E., Danielsen, Mia, Bengtson, N. S., Kunze, M. B. A., Kubiak, X., Sminia, T. J., Løper, J. H., Tran, P. T., Lindorff-Larsen, Kresten, Rasmussen, Søren Gøgsig Faarup, Mathiesen, Jesper M. & Pedersen, D. S., 2018, In: RSC Advances. 8, 4, p. 2219-2228 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

    Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Yeast surface display platform for rapid discovery of conformationally selective nanobodies

    McMahon, C., Baier, A. S., Pascolutti, R., Wegrecki, M., Zheng, S., Ong, J. X., Erlandson, S. C., Hilger, D., Rasmussen, Søren Gøgsig Faarup, Ring, A. M., Manglik, A. & Kruse, A. C., 2018, In: Nature Structural and Molecular Biology. 25, 3, p. 289-296 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2019
  33. Published

    Assembly of a GPCR-G Protein Complex

    Du, Y., Duc, N. M., Rasmussen, Søren Gøgsig Faarup, Hilger, D., Kubiak, X., Wang, L., Bohon, J., Kim, H. R., Wegrecki, M., Asuru, A., Jeong, K. M., Lee, J., Chance, M. R., Lodowski, D. T., Kobilka, B. K. & Chung, K. Y., 2019, In: Cell. 177, 5, p. 1232-1242

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Substrate-Induced Conformational Dynamics of the Dopamine Transporter

    Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 7932