Søren Gøgsig Faarup Rasmussen
Associate Professor
Neuropharm and Genetics
Blegdamsvej 3
2200 København N.
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Substrate-induced conformational dynamics of the dopamine transporter
Nielsen, A. K., Möller, I. R., Wang, Y., Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.Research output: Contribution to journal › Journal article › Research › peer-review
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A general protocol for the generation of Nanobodies for structural biology
Pardon, E., Laeremans, T., Triest, S., Rasmussen, Søren Gøgsig Faarup, Wohlkönig, A., Ruf, A., Muyldermans, S., Hol, W. G. J., Kobilka, B. K. & Steyaert, J., Mar 2014, In: Nature Protocols (Print). 9, 3, p. 674-93 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of pH on ß2 adrenoceptor function
Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik & Kobilka, B. K., 2000, In: Journal of Biological Chemistry. 5, Vol. 275, p. 3121-3127Research output: Contribution to journal › Journal article › Research › peer-review
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Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites
Plenge, P., Gether, Ulrik & Rasmussen, Søren Gøgsig Faarup, 2007, In: European Journal of Pharmacology. 567, 1-2, p. 1-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy
Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and fluorescent labeling of the human serotonin transporter
Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In: Biochemistry. 44, 9, p. 3494-505 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor
Rasmussen, Søren Gøgsig Faarup, Choi, H., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 175-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
Rasmussen, Søren Gøgsig Faarup, Choi, H., Rosenbaum, D. M., Kobilka, T. S., Thian, F. S., Edwards, P. C., Burghammer, M., Ratnala, V. R. P., Sanishvili, R., Fischetti, R. F., Schertler, G. F. X., Weis, W. I. & Kobilka, B. K., 15 Nov 2007, In: Nature. 450, 7168, p. 383-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanisms of GPCR activation
Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2006, G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity. 2006: Wiley, Vol. 24. p. 27-42 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI
Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In: Molecular Pharmacology. 56, p. 175-184Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure of the β2 adrenergic receptor-Gs protein complex
Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, Jesper M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K., 29 Sep 2011, In: Nature. 477, 7366, p. 549-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter
Rasmussen, Søren Gøgsig Faarup, Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (7), p. 4717-4723Research output: Contribution to journal › Journal article › Research › peer-review
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Understanding G-protein coupled receptors and their role in the CNS
Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
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Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4
Richter, W., Day, P., Agrawal, R., Bruss, M. D., Granier, S., Wang, Y. L., Rasmussen, Søren Gøgsig Faarup, Horner, K., Wang, P., Lei, T., Patterson, A. J., Kobilka, B. & Conti, M., 23 Jan 2008, In: E M B O Journal. 27, 2, p. 384-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The beta2 Adrenergic Receptor as a Model for G Protein-Coupled Receptor Structure and Activation by Diffusible Hormones
Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & Kobilka, B., Sep 2009, Handbook of Cell Signaling. Elsevier EditoraResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
Rosenbaum, D. M., Cherezov, V., Hanson, M. A., Rasmussen, Søren Gøgsig Faarup, Thian, F. S., Kobilka, T. S., Choi, H., Yao, X., Weis, W. I., Stevens, R. C. & Kobilka, B. K., 23 Nov 2007, In: Science (New York, N.Y.). 318, 5854, p. 1266-73 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and function of an irreversible agonist-β(2) adrenoceptor complex
Rosenbaum, D. M., Zhang, C., Lyons, J. A., Holl, R., Aragao, D., Arlow, D. H., Rasmussen, Søren Gøgsig Faarup, Choi, H., Devree, B. T., Sunahara, R. K., Chae, P. S., Gellman, S. H., Dror, R. O., Shaw, D. E., Weis, W. I., Caffrey, M., Gmeiner, P. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 236-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure and function of G-protein-coupled receptors
Rosenbaum, D. M., Rasmussen, Søren Gøgsig Faarup & Kobilka, B. K., 21 May 2009, In: Nature. 459, 7245, p. 356-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum
Selao, T. T., Branca, R., Chae, P. S., Lehtiö, J., Gellman, S. H., Rasmussen, Søren Gøgsig Faarup, Nordlund, S. & Norén, A., 3 Jun 2011, In: Journal of Proteome Research. 10, 6, p. 2703-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies
Staus, D. P., Wingler, L. M., Strachan, R. T., Rasmussen, Søren Gøgsig Faarup, Pardon, E., Ahn, S., Steyaert, J., Kobilka, B. K. & Lefkowitz, R. J., Mar 2014, In: Molecular Pharmacology. 85, 3, p. 472-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing Activation and Conformational Dynamics of the Vesicle-Reconstituted β2 Adrenergic Receptor at the Single-Molecule Level
Tutkus, M., Lundgaard, C. V., Veshaguri, S., Tønnesen, A., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2024, In: Journal of Physical Chemistry B. 128, 9, p. 2124–2133 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level
Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs
Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal Structures of the ß2-Adrenergic Receptor
Weis, W. I., Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & et. al, E. A., 2009, From Molecules to Medicines, Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism. Springer, p. 217-230 14 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex
Westfield, G. H., Rasmussen, Søren Gøgsig Faarup, Su, M., Dutta, S., DeVree, B. T., Chung, K. Y., Calinski, D., Velez-Ruiz, G., Oleskie, A. N., Pardon, E., Chae, P. S., Liu, T., Li, S., Woods, V. L., Steyaert, J., Kobilka, B. K., Sunahara, R. K. & Skiniotis, G., 20 Sep 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 16086-91 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 7932
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Ligand modulation of sidechain dynamics in a wild-type human GPCR
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Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor
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115
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Substrate-induced conformational dynamics of the dopamine transporter
Research output: Contribution to journal › Journal article › Research › peer-review
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