R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse

Research output: Contribution to journalJournal articleResearchpeer-review

  • Løland, Claus Juul
  • Maddalena Mereu
  • Oluyomi M Okunola
  • Jianjing Cao
  • Thomas E Prisinzano
  • Sonia Mazier
  • Theresa Kopajtic
  • Lei Shi
  • Jonathan L Katz
  • Gianluigi Tanda
  • Amy Hauck Newman
(±)-Modafinil has piqued interest as a treatment for attention-deficit/hyperactivity disorder and stimulant dependence. The R-enantiomer of modafinil might have unique pharmacological properties that should be further investigated.
Original languageEnglish
JournalBiological Psychiatry
Volume72
Issue number5
Pages (from-to)405-13
Number of pages9
ISSN0006-3223
DOIs
Publication statusPublished - Sep 2012

    Research areas

  • Animals, Benzhydryl Compounds, Central Nervous System Stimulants, Cocaine, Dopamine, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, Humans, Male, Mice, Microdialysis, Nucleus Accumbens, Protein Binding, Substance-Related Disorders

ID: 44290422