Claus Juul Løland

Claus Juul Løland

Professor


  1. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding

    Loland, Claus Juul, Grånäs, C., Javitch, J. A. & Gether, Ulrik, 30 Jan 2004, In: The Journal of Biological Chemistry. 279, 5, p. 3228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Allosteric Binding in the Serotonin Transporter - Pharmacology, Structure, Function and Potential Use as a Novel Drug Target

    Loland, Claus Juul, Sanchez, C., Plenge, P., Bøgesø, K. P. & Bang-Andersen, B., 2017, Allosterism in Drug Discovery. Royal Society of Chemistry, p. 360-380 21 p. (RSC Drug Discovery Series; No. 56).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. Published

    Transmembrane transporter proteins: Capturing transport in motion

    Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  6. Published

    R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse

    Loland, Claus Juul, Mereu, M., Okunola, O. M., Cao, J., Prisinzano, T. E., Mazier, S., Kopajtic, T., Shi, L., Katz, J. L., Tanda, G. & Newman, A. H., Sep 2012, In: Biological Psychiatry. 72, 5, p. 405-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    3,4-Bis(hydroxymethyl)hexane-1,6-diol-based Maltosides (HDMs) for Membrane-Protein Study: Importance of Detergent Rigidity-Flexibility Balance in Protein Stability

    Lee, H. S., Das, M., Mahler, F., Ahmed, W., Wang, H., Mortensen, Jonas Sigurd, Hariharan, P., Ghani, L., Byrne, B., Guan, L., Loland, Claus Juul, Keller, S. & Chae, P. S., 2022, In: Chemistry - An Asian Journal. 17, 24, 9 p., e202200941.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Development of 1,3-acetonedicarboxylate-derived glucoside amphiphiles (ACAs) for membrane protein study

    Lee, H. J., Ehsan, M., Zhang, X., Katsube, S., Munk, C. F., Wang, H., Ahmed, W., Kumar, A., Byrne, B., Loland, Claus Juul, Guan, L., Liu, X. & Chae, P. S., 2022, In: Chemical Science. 13, p. 5750-5759 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Series of (([1,1′-Biphenyl]-2-yl)methyl)sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity

    Ku, T. C., Cao, J., Won, S. J., Guo, J., Camacho-Hernandez, G. A., Okorom, A. V., Salomon, Kristine Walløe, Lee, K. H., Loland, Claus Juul, Duff, H. J., Shi, L. & Newman, A. H., 2024, In: ACS Pharmacology and Translational Science. 7, 2, p. 515-532 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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