Andreas Toft Sørensen

Andreas Toft Sørensen

Associate Professor

ORCID: 0000-0001-5887-9247

Publication year:
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1 - 43 out of 43Page size: 100
  1. 2023
  2. Published

    Behavioral encoding across timescales by region-specific dopamine dynamics

    Jørgensen, Søren Heide, Ejdrup, Aske Lykke, Lycas, M. D., Posselt, Leonie Pauline, Madsen, Kenneth Lindegaard, Tian, L., Dreyer, J. K., Herborg, Freja, Sørensen, Andreas Toft & Gether, Ulrik, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, 10 p., e2215230120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Detection of endogenous NPY release determined by novel GRAB sensor in cultured cortical neurons

    Christensen, Emma Kragelund, Konomi Pilkati, Ainoa, Rombach, Joscha, Comaposada Baro, Raquel, Wang, H., Li, Y. & Sørensen, Andreas Toft, 2023, In: Frontiers in Cellular Neuroscience. 17, 12 p., 1221147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Neuronal activity dynamics in the dentate gyrus during early epileptogenesis

    Berglind, F., Boulot, A., Gonzalez-Ramos, A., Melin, Esbjörn Aage Anders, Bono, A., Sørensen, Andreas Toft & Ledri, M., 2023, In: Epilepsy Research. 194, 10 p., 107182.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2022
  6. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity

    Lycas, M. D., Ejdrup, Aske Lykke, Sørensen, Andreas Toft, Haahr, N. O., Jørgensen, Søren Heide, Guthrie, D. A., Støier, J. F., Werner, C., Newman, A. H., Sauer, M., Herborg, Freja & Gether, Ulrik, 2022, In: Cell Reports. 40, 13, 27 p., 111431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Stabilization of V1 interneuron-motor neuron connectivity ameliorates motor phenotype in a mouse model of ALS

    Mora, S., Friis, R. V. H., Stuckert, A., Noes-Holt, Gith, Montañana-Rosell, Roser, Sørensen, Andreas Toft, Selvan, Raghav & Allodi, Ilary, 2022, 10 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  9. Published

    The Scaffold Protein PICK1 as a Target in Chronic Pain

    Sørensen, Andreas Toft, Rombach, Joscha, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2022, In: Cells. 11, 8, 1255.

    Research output: Contribution to journal › Review › Research › peer-review

  10. 2021
  11. Published

    A Novel Peripheral Action of PICK1 Inhibition in Inflammatory Pain

    Jensen, Kathrine Louise, Noes-Holt, Gith, Sørensen, Andreas Toft & Madsen, Kenneth Lindegaard, 2021, In: Frontiers in Cellular Neuroscience. 15, 13 p., 750902.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies

    Ledri, M., Sørensen, Andreas Toft, Kokaia, M., Woldbye, David Paul Drucker & Gøtzsche, C. R., 2021, In: Frontiers in Molecular Neuroscience. 14, 778134.

    Research output: Contribution to journal › Editorial › Research › peer-review

  13. Published

    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

    Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, Galli, A., Hjermind, L. E., Gether, Ulrik & IPSYCH Researchers, I. R., 2021, In: JCI insight. 6, 18, 21 p., 151496.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2020
  15. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Functionally Distinct Neuronal Ensembles within the Memory Engram

    Sun, X., Bernstein, M. J., Meng, M., Rao, S., Sørensen, Andreas Toft, Yao, L., Zhang, X., Anikeeva, P. O. & Lin, Y., 2020, In: Cell. 181, 2, p. 410-423 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2019
  18. Published

    Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

    Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, Nikolaj Winther, Jørgensen, Søren Heide, McGirr, J. C., de Diego Ajenjo, A., Sørensen, Andreas Toft, Perrier, Jean-Francois Marie, Petersen, A., Gether, Ulrik, Woldbye, David Paul Drucker & Andreasen T., Jesper, 2019, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges

    Runegaard, A. H., Fitzpatrick, C. M., Woldbye, David Paul Drucker, Andreasen T., Jesper, Sørensen, Andreas Toft & Gether, Ulrik, 2019, In: Pharmacological Reviews. 71, 2, p. 123-156 34 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats

    Soud, K., Jørgensen, Søren Heide, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, 2019, In: Journal of Neuroscience Research. 97, 3, p. 362-372 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2018
  22. Published

    Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females

    Dolzani, S. D., Baratta, M. V., Moss, J. M., Leslie, N. L., Tilden, S. G., Sørensen, Andreas Toft, Watkins, L. R., Lin, Y. & Maier, S. F., 26 Feb 2018, In: eNeuro. 5, 1, p. 1-18 18 p., e0025-18.2018.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

    Runegaard, A. H., Sørensen, Andreas Toft, Fitzpatrick, C. M., Jørgensen, Søren Heide, Petersen, A. V., Hansen, Nikolaj Winther, Weikop, Pia, Andreasen T., Jesper, Mikkelsen, Jens D., Perrier, Jean-Francois Marie, Woldbye, David Paul Drucker, Rickhag, Karl Mattias, Wörtwein, Gitta & Gether, Ulrik, 2018, In: eNeuro. 5, 3, 26 p., e0345.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation

    Weng, F., Garcia, R. I., Lutzu, S., Alviña, K., Zhang, Y., Dushko, M., Ku, T., Zemoura, K., Rich, D., Garcia-Dominguez, D., Hung, M., Yelhekar, T. D., Sørensen, Andreas Toft, Xu, W., Chung, K., Castillo, P. E. & Lin, Y., 2018, In: Neuron. 97, 5, p. 1137-1152 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2017
  26. Published

    Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

    Sørensen, Andreas Toft, Ledri, M., Melis, M., Nikitidou Ledri, L., Andersson, M. & Kokaia, M., 7 Dec 2017, In: eNeuro. 4, 6, e0172-17.2017 1–10.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research

    Jørgensen, Søren Heide, Fitzpatrick, C. M., Gether, Ulrik, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, Nov 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. 2016

  29. A robust activity marking system for exploring active neuronal ensembles

    Sørensen, Andreas Toft, Cooper, Y. A., Baratta, M. V., Weng, F., Zhang, Y., Ramamoorthi, K., Fropf, R., LaVerriere, E., Xue, J., Young, A., Schneider, C., Gotzsche, C. R., Hemberg, M., Yin, J. C. P., Maier, S. F. & Lin, Y., 23 Sep 2016, In: eLife. 5, 9, 28 p., e13918.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2015
  31. Published

    Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus

    Ledri, M., Sørensen, Andreas Toft, Madsen, M. G., Christiansen, S. H., Ledri, L. N., Cifra, A., Bengzon, J., Lindberg, E., Pinborg, L. H., Jespersen, B., Gotzsche, C. R., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 1 Jul 2015, In: Journal of Neuroscience. 35, 26, p. 9622-9631 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2014

  33. Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors

    Avaliani, N., Sørensen, Andreas Toft, Ledri, M., Bengzon, J., Koch, P., Brüstle, O., Deisseroth, K., Andersson, M. & Kokaia, M., Dec 2014, In: Stem Cells. 32, 12, p. 3088-98 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Noninvasive optical inhibition with a red-shifted microbial rhodopsin

    Chuong, A. S., Miri, M. L., Busskamp, V., Matthews, G. A. C., Acker, L. C., Sørensen, A. T., Young, A., Klapoetke, N. C., Henninger, M. A., Kodandaramaiah, S. B., Ogawa, M., Ramanlal, S. B., Bandler, R. C., Allen, B. D., Forest, C. R., Chow, B. Y., Han, X., Lin, Y., Tye, K. M., Roska, B. & 2 others, Cardin, J. A. & Boyden, E. S., 2014, In: Nature Neuroscience. 17, 8, p. 1123-1129 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

    Berglind, F., Ledri, M., Sørensen, Andreas Toft, Nikitidou, L., Melis, M., Bielefeld, P., Kirik, D., Deisseroth, K., Andersson, M. & Kokaia, M., 2014, In: Neurobiology of Disease. 65, p. 133-141 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2013
  37. Published

    Jasper’s Basic mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y

    Noe, F., Sørensen, Andreas Toft, Kokaia, M. & Vezzani, A., 2013, Jasper's Basic Mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y. Noebels, J. L., Avoli, M., Rogawski, M. A., Olsen, R. W. & Delgado-Escueta, A. V. (eds.). 4 ed. Oxford University Press, p. 1139-1149 11 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  38. Novel approaches to epilepsy treatment

    Sørensen, Andreas Toft & Kokaia, M., 2013, In: Epilepsia. 54, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. 2012
  40. Published

    Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures.

    Gøtzsche, C. R., Nikitidou, L., Sørensen, Andreas Toft, Olesen, M. V., Sørensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, David Paul Drucker & Kokaia, M., 2012, In: Neurobiology of Disease. 45, p. 288-96 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2011
  42. Published

    Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons

    Sørensen, Andreas Toft, Rogelius, N., Lundberg, C. & Kokaia, M., Jun 2011, In: Experimental Neurology. 229, 2, p. 274-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model

    Tønnesen, J., Parish, C. L., Sørensen, Andreas Toft, Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O. & Kokaia, M., 4 Mar 2011, In: PLOS ONE. 6, 3, p. e17560

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Tuning afferent synapses of hippocampal interneurons by neuropeptide Y

    Ledri, M., Sørensen, Andreas Toft, Erdelyi, F., Szabo, G. & Kokaia, M., Feb 2011, In: Hippocampus. 21, 2, p. 198-211 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The treatment of neurological diseases under a new light: the importance of optogenetics

    Kokaia, M. & Sørensen, Andreas Toft, Jan 2011, In: Drugs of Today. 47, 1, p. 53-62 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. 2010
  47. Published

    Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures

    Woldbye, David Paul Drucker, Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, Andreas Toft, Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sep 2010, In: Brain. 133, 9, p. 2778-88 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2009
  49. Published

    Optogenetic control of epileptiform activity

    Tønnesen, J., Sørensen, Andreas Toft, Deisseroth, K., Lundberg, C. & Kokaia, M., 21 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 29, p. 12162-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides

    Kokaia, M. & Sørensen, Andreas Toft, 27 May 2009, Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides. Schwartzkroin, PA. (ed.). Elsevier Ltd. Academic Press, Vol. 3. p. 1430-34 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review

  51. Published

    Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP

    Sørensen, Andreas Toft, Nikitidou, L., Ledri, M., Lin, E. D., During, M. J., Kanter-Schlifke, I. & Kokaia, M., Feb 2009, In: Experimental Neurology. 215, 2, p. 328-33 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Treatments (Non-Antiepileptic Drugs): Epilepsy and Gene Therapy: Resculpturing Synaptic Transmission with Neuropeptides

    Kokaia, M. & Sørensen, Andreas Toft, 1 Jan 2009, Encyclopedia of Basic Epilepsy Research. Elsevier Science Inc., p. 1430-1434 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  53. 2008
  54. Published

    Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum

    Sørensen, Andreas Toft, Kanter-Schlifke, I., Lin, E. D., During, M. J. & Kokaia, M., Oct 2008, In: Molecular and Cellular Neuroscience. 39, 2, p. 229-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

    Parish, C. L., Castelo-Branco, G., Rawal, N., Tonnesen, J., Sørensen, Andreas Toft, Salto, C., Kokaia, M., Lindvall, O. & Arenas, E., Jan 2008, In: The Journal of Clinical Investigation. 118, 1, p. 149-60 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning

    Sørensen, Andreas Toft, Kanter-Schlifke, I., Carli, M., Balducci, C., Noe, F., During, M. J., Vezzani, A. & Kokaia, M., 2008, In: Hippocampus. 18, 6, p. 564-74 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2007
  58. Published

    Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity

    Kanter-Schlifke, I., Sørensen, Andreas Toft, Ledri, M., Kuteeva, E., Hökfelt, T. & Kokaia, M., 19 Dec 2007, In: Neuroscience. 150, 4, p. 984-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2005
  60. Published

    Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

    Woldbye, David Paul Drucker, Nanobashvili, A., Sørensen, Andreas Toft, Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts

    Sørensen, Andreas Toft, Thompson, L., Kirik, D., Björklund, A., Lindvall, O. & Kokaia, M., May 2005, In: European Journal of Neuroscience. 21, 10, p. 2793-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 144763187