Andreas Toft Sørensen

Andreas Toft Sørensen

Associate Professor


  1. Published

    A Novel Peripheral Action of PICK1 Inhibition in Inflammatory Pain

    Jensen, Kathrine Louise, Noes-Holt, Gith, Sørensen, Andreas Toft & Madsen, Kenneth Lindegaard, 2021, In: Frontiers in Cellular Neuroscience. 15, 13 p., 750902.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. A robust activity marking system for exploring active neuronal ensembles

    Sørensen, Andreas Toft, Cooper, Y. A., Baratta, M. V., Weng, F., Zhang, Y., Ramamoorthi, K., Fropf, R., LaVerriere, E., Xue, J., Young, A., Schneider, C., Gotzsche, C. R., Hemberg, M., Yin, J. C. P., Maier, S. F. & Lin, Y., 23 Sep 2016, In: eLife. 5, 9, 28 p., e13918.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons

    Sørensen, Andreas Toft, Rogelius, N., Lundberg, C. & Kokaia, M., Jun 2011, In: Experimental Neurology. 229, 2, p. 274-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum

    Sørensen, Andreas Toft, Kanter-Schlifke, I., Lin, E. D., During, M. J. & Kokaia, M., Oct 2008, In: Molecular and Cellular Neuroscience. 39, 2, p. 229-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures

    Woldbye, David Paul Drucker, Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, Andreas Toft, Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sep 2010, In: Brain. 133, 9, p. 2778-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

    Sørensen, Andreas Toft, Ledri, M., Melis, M., Nikitidou Ledri, L., Andersson, M. & Kokaia, M., 7 Dec 2017, In: eNeuro. 4, 6, e0172-17.2017 1–10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Behavioral encoding across timescales by region-specific dopamine dynamics

    Jørgensen, Søren Heide, Ejdrup, Aske Lykke, Lycas, M. D., Posselt, Leonie Pauline, Madsen, Kenneth Lindegaard, Tian, L., Dreyer, J. K., Herborg, Freja, Sørensen, Andreas Toft & Gether, Ulrik, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, 10 p., e2215230120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners

    Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research

    Jørgensen, Søren Heide, Fitzpatrick, C. M., Gether, Ulrik, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, Nov 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures.

    Gøtzsche, C. R., Nikitidou, L., Sørensen, Andreas Toft, Olesen, M. V., Sørensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, David Paul Drucker & Kokaia, M., 2012, In: Neurobiology of Disease. 45, p. 288-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Detection of endogenous NPY release determined by novel GRAB sensor in cultured cortical neurons

    Christensen, Emma Kragelund, Konomi Pilkati, Ainoa, Rombach, Joscha, Comaposada Baro, Raquel, Wang, H., Li, Y. & Sørensen, Andreas Toft, 2023, In: Frontiers in Cellular Neuroscience. 17, 12 p., 1221147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus

    Ledri, M., Sørensen, Andreas Toft, Madsen, M. G., Christiansen, S. H., Ledri, L. N., Cifra, A., Bengzon, J., Lindberg, E., Pinborg, L. H., Jespersen, B., Gotzsche, C. R., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 1 Jul 2015, In: Journal of Neuroscience. 35, 26, p. 9622-9631 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

    Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, Nikolaj Winther, Jørgensen, Søren Heide, McGirr, J. C., de Diego Ajenjo, A., Sørensen, Andreas Toft, Perrier, Jean-Francois Marie, Petersen, A., Gether, Ulrik, Woldbye, David Paul Drucker & Andreasen T., Jesper, 2019, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

    Woldbye, David Paul Drucker, Nanobashvili, A., Sørensen, Andreas Toft, Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Editorial: Gene Therapy in the CNS – Progress and Prospects for Novel Therapies

    Ledri, M., Sørensen, Andreas Toft, Kokaia, M., Woldbye, David Paul Drucker & Gøtzsche, C. R., 2021, In: Frontiers in Molecular Neuroscience. 14, 778134.

    Research output: Contribution to journalEditorialResearchpeer-review

  17. Published

    Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides

    Kokaia, M. & Sørensen, Andreas Toft, 27 May 2009, Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides. Schwartzkroin, PA. (ed.). Elsevier Ltd. Academic Press, Vol. 3. p. 1430-34 5 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearchpeer-review

  18. Published

    Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model

    Tønnesen, J., Parish, C. L., Sørensen, Andreas Toft, Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O. & Kokaia, M., 4 Mar 2011, In: PLOS ONE. 6, 3, p. e17560

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts

    Sørensen, Andreas Toft, Thompson, L., Kirik, D., Björklund, A., Lindvall, O. & Kokaia, M., May 2005, In: European Journal of Neuroscience. 21, 10, p. 2793-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Functionally Distinct Neuronal Ensembles within the Memory Engram

    Sun, X., Bernstein, M. J., Meng, M., Rao, S., Sørensen, Andreas Toft, Yao, L., Zhang, X., Anikeeva, P. O. & Lin, Y., 2020, In: Cell. 181, 2, p. 410-423 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity

    Kanter-Schlifke, I., Sørensen, Andreas Toft, Ledri, M., Kuteeva, E., Hökfelt, T. & Kokaia, M., 19 Dec 2007, In: Neuroscience. 150, 4, p. 984-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP

    Sørensen, Andreas Toft, Nikitidou, L., Ledri, M., Lin, E. D., During, M. J., Kanter-Schlifke, I. & Kokaia, M., Feb 2009, In: Experimental Neurology. 215, 2, p. 328-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

    Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, Galli, A., Hjermind, L. E., Gether, Ulrik & IPSYCH Researchers, I. R., 2021, In: JCI insight. 6, 18, 21 p., 151496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females

    Dolzani, S. D., Baratta, M. V., Moss, J. M., Leslie, N. L., Tilden, S. G., Sørensen, Andreas Toft, Watkins, L. R., Lin, Y. & Maier, S. F., 26 Feb 2018, In: eNeuro. 5, 1, p. 1-18 18 p., e0025-18.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Jasper’s Basic mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y

    Noe, F., Sørensen, Andreas Toft, Kokaia, M. & Vezzani, A., 2013, Jasper's Basic Mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y. Noebels, J. L., Avoli, M., Rogawski, M. A., Olsen, R. W. & Delgado-Escueta, A. V. (eds.). 4 ed. Oxford University Press, p. 1139-1149 11 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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