Nanna MacAulay
Professor
Molecular Neuroscience
Blegdamsvej 3
2200 København N.
- Published
Cerebrospinal fluid osmolality cannot predict development or surgical outcome of idiopathic normal pressure hydrocephalus
Ørnbo, E. K., Steffensen, Annette Buur, Gredal, Hanne Birgit, Poulsen, Helle Harding, Rostgaard, Nina, Rasmussen, C. H., Møller-Nissen, M., Simonsen, A. H., Hasselbalch, Steen, Juhler, Marianne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 9 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
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Passive water transport in biological pores
Zeuthen, Thomas & MacAulay, Nanna, 2002, In: International Review of Cytology. 215, p. 203-230Research output: Contribution to journal › Journal article › Research › peer-review
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Cotransporters as molecular water pumps
Zeuthen, Thomas & MacAulay, Nanna, 2002, In: International Review of Cytology. 215, p. 259-84 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Osmotic water transport in aquaporins: evidence for a stochastic mechanism
Zeuthen, Thomas, Alsterfjord, M., Beitz, E. & MacAulay, Nanna, 15 Oct 2013, In: Journal of Physiology. 591, Pt 20, p. 5017-29 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cotransport of water by Na¿-K¿-2Cl¿ cotransporters expressed in Xenopus oocytes: NKCC1 versus NKCC2
Zeuthen, Thomas & MacAulay, Nanna, 1 Mar 2012, In: Journal of Physiology. 590, Pt 5, p. 1139-54 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Water transport by GLUT2 expressed in Xenopus laevis oocytes
Zeuthen, Thomas, Zeuthen, E. & MacAulay, Nanna, 2007, In: Journal of Physiology. 579, 2, p. 345-361 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration
Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C. A., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rigmor Højland & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86Research output: Contribution to journal › Journal article › Research › peer-review
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The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion
Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension
Wardman, Jonathan Henry, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Jensen, Mette Nyholm, Wilhjelm, J. E., Styrishave, Bjarne, Hamann, Steffen, Heegaard, Steffen, Sinclair, A. J. & MacAulay, Nanna, 2024, In: Fluids and Barriers of the CNS. 21, 1, 20 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
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Modelling idiopathic intracranial hypertension in rats: contributions of high fat diet and testosterone to intracranial pressure and cerebrospinal fluid production
Wardman, Jonathan Henry, Jensen, Mette Nyholm, Andreassen, Søren Norge, Styrishave, Bjarne, Wilhjelm, J. E., Sinclair, A. J. & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 17 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
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Cl- channels in apoptosis
Wanitchakool, P., Ousingsawat, J., Sirianant, L., MacAulay, Nanna, Schreiber, R. & Kunzelmann, K., Oct 2016, In: European biophysics journal : EBJ. 45, 7, p. 599-610 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DRAIN - Double-blind Randomized Acetazolamide trial in Idiopathic Normal pressure hydrocephalus
Virhammar, J., Braun, M., Ekblom, M., Fasth, O., Fallmar, D., Laurell, K., MacAulay, Nanna & Nyholm, D., 2022, In: Fluids and Barriers of the CNS. 19, Supplement 1, p. 10 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor
Toft-Bertelsen, Trine Lisberg, Larsen, B. R., Christensen, S. K., Khandelia, H., Waagepetersen, Helle S. & MacAulay, Nanna, 2020, In: Glia. 69, 1, p. 28-41 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1
Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Heerfordt, E. K., Lolansen, Sara Diana, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Rath, Martin Fredensborg, Juhler, Marianne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
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Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain
Toft-Bertelsen, Trine Lisberg, Yarishkin, O., Redmon, S., Phuong, T. T. T., Krizaj, D. & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 48, p. 18421-18434 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct Cerebrospinal Fluid Lipid Signature in Patients with Subarachnoid Hemorrhage-Induced Hydrocephalus
Toft-Bertelsen, Trine Lisberg, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Juhler, Marianne & MacAulay, Nanna, 2023, In: Biomedicines. 11, 9, 14 p., 2360.Research output: Contribution to journal › Journal article › Research › peer-review
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TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Cells. 10, 1, 16 p., 165.Research output: Contribution to journal › Review › Research › peer-review
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TRPing on Cell Swelling-TRPV4 Senses It
Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Frontiers in Immunology. 12, 9 p., 730982.Research output: Contribution to journal › Review › Research › peer-review
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When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor
Toft-Bertelsen, Trine Lisberg, Križaj, D. & MacAulay, Nanna, 2017, In: Journal of Physiology. 595, 11, p. 3287-3302 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sensing and regulation of cell volume - we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?
Toft-Bertelsen, Trine Lisberg, Larsen, B. R. & MacAulay, Nanna, 2018, In: Channels (Austin). 12, 1, p. 100-108Research output: Contribution to journal › Review › Research › peer-review
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When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor
Toft-Bertelsen, Trine Lisberg, Križaj, D. & MacAulay, Nanna, 1 Jun 2017, In: The Journal of Physiology. 595, 11, p. 3287-3302 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Toward New AQP4 Inhibitors: ORI-TRN-002
Thormann, M., Traube, N., Yehia, N., Koestler, R., Galabova, G., MacAulay, Nanna & Toft-Bertelsen, Trine Lisberg, 2024, In: International Journal of Molecular Sciences. 25, 2, 11 p., 924.Research output: Contribution to journal › Journal article › Research › peer-review
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Ammonium ion transport by the AMT/Rh homolog TaAMT1;1 is stimulated by acidic pH
Søgaard, R., Alsterfjord, M., MacAulay, Nanna & Zeuthen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 458, 4, p. 733-43 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional modulation of the glutamate transporter variant GLT1b by the PDZ domain protein PICK1
Søgaard, R., Borre, L., Braunstein, T. H., Madsen, Kenneth Lindegaard & MacAulay, Nanna, 12 Jul 2013, In: The Journal of Biological Chemistry. 288, 28, p. 20195-207 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated ammonium levels: differential acute effects on three glutamate transporter isoforms
Søgaard, R., Novak, Ivana & MacAulay, Nanna, 2012, In: American Journal of Physiology: Cell Physiology. 302, 6, p. C880-C891 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The α2β2 isoform combination dominates the astrocytic Na+/K+-ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation
Stoica, A., Larsen, B. R., Assentoft, M., Holm, R., Holt, L. M., Vilhardt, Frederik, Vilsen, B., Lykke-Hartmann, K., Olsen, M. L. & MacAulay, Nanna, 2017, In: Glia. 65, 11, p. 1777-1793 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nocturnal increase in cerebrospinal fluid secretion as a circadian regulator of intracranial pressure
Steffensen, Annette Buur, Edelbo, Beatriche Louise, Barbuskaite, Dagne, Andreassen, Søren Norge, Olsen, M. H., Møller, Kirsten & MacAulay, Nanna, 2023, In: Fluids and Barriers of the CNS. 20, 1, 14 p., 49.Research output: Contribution to journal › Journal article › Research › peer-review
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Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Steffensen, Annette Buur, Oernbo, E. K., Stoica, A., Gerkau, N. J., Barbuskaite, Dagne, Tritsaris, Katerina, Rose, C. R. & MacAulay, Nanna, 2018, In: Nature Communications. 9, 1, 13 p., 2167.Research output: Contribution to journal › Journal article › Research › peer-review
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Chloride Cotransporters as a Molecular Mechanism underlying Spreading Depolarization-Induced Dendritic Beading
Steffensen, Annette Buur, Sword, J., Croom, D., Kirov, S. A. & MacAulay, Nanna, 2 Sep 2015, In: Journal of Neuroscience. 35, 35, p. 12172-12187 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson’s disease
Stahl, K., Rahmani, S., Prydz, A., Skauli, N., MacAulay, Nanna, Mylonakou, M. N., Torp, R., Skare, Ø., Berg, T., Leergaard, T. B., Paulsen, R. E., Ottersen, O. P. & Amiry-Moghaddam, M., 2018, In: PLOS ONE. 13, 3, e0194896.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of Kir4.1 and Kir4.1-Kir5.1 channels by small changes in cell volume
Soe, R., MacAulay, Nanna & Klærke, Dan Arne, Jun 2009, In: Neuroscience Letters. 457, 2, p. 80-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia
Ryskamp, D. A., Jo, A. O., Frye, A. M., Vazquez-Chona, F., MacAulay, Nanna, Thoreson, W. B. & Križaj, D., 19 Nov 2014, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 47, p. 15689-700 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inflammatory Markers as Predictors of Shunt Dependency and Functional Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage
Rostgaard, Nina, Olsen, M. H., Capion, T., MacAulay, Nanna & Juhler, Marianne, 2023, In: Biomedicines. 11, 4, 14 p., 997.Research output: Contribution to journal › Journal article › Research › peer-review
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Ventricular CSF proteomic profiles and predictors of surgical treatment outcome in chronic hydrocephalus
Rostgaard, Nina, Olsen, M. H., Lolansen, Sara Diana, Nørager, N. H., Plomgaard, Peter Stendahl, MacAulay, Nanna & Juhler, Marianne, 2023, In: Acta Neurochirurgica. 165, p. 4059–4070 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential proteomic profile of lumbar and ventricular cerebrospinal fluid
Rostgaard, Nina, Olsen, M. H., Ottenheijm, Maud Eline, Drici, L., Simonsen, A. H., Plomgaard, Peter Stendahl, Gredal, Hanne Birgit, Poulsen, Helle Harding, Zetterberg, H., Blennow, K., Hasselbalch, Steen, MacAulay, Nanna & Juhler, Marianne, 2023, In: Fluids and Barriers of the CNS. 20, 1, 13 p., 6.Research output: Contribution to journal › Journal article › Research › peer-review
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The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation
Rosenbaek, L. L., Rizzo, F., Wu, Q., Rojas-Vega, L., Gamba, G., MacAulay, Nanna, Staub, O. & Fenton, R. A., Dec 2017, In: Scientific Reports. 7, 15 p., 12981.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells
Rosenbaek, L. L., Rizzo, F., MacAulay, Nanna, Staub, O. & Fenton, R. A., Aug 2017, In: American Journal of Physiology: Renal Physiology. 313, 2, p. F495-F504Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC
Rosenbaek, L. L., Assentoft, M., Pedersen, N. B., MacAulay, Nanna & Fenton, R. A., 1 Dec 2012, In: Journal of Physiology. 590, Pt 23, p. 6121-39 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis
Razzaghi Khamesi, P., Charitatos, V., Heerfordt, E. K., MacAulay, Nanna & Kurtcuoglu, V., 2023, In: Fluids and Barriers of the CNS. 20, 1, 13 p., 18.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-activity relationships of bumetanide derivatives: correlation between diuretic activity in dogs and inhibition of the human NKCC2A transporter
Pedersen, K. L., Töllner, K., Römermann, K., Feit, P. W., Erker, T., MacAulay, Nanna & Löscher, W., Sep 2015, In: British Journal of Pharmacology. 172, 18, p. 4464-4480 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vasopressin receptors V1a and V2 are not osmosensors
Pedersen, K. L., Assentoft, M., Fenton, R. A., Rosenkilde, Mette & MacAulay, Nanna, Aug 2015, In: Physiological Reports. 3, 8, 11 p., e12519.Research output: Contribution to journal › Journal article › Research › peer-review
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The search for NKCC1-selective drugs for the treatment of epilepsy: Structure-function relationship of bumetanide and various bumetanide derivatives in inhibiting the human cation-chloride cotransporter NKCC1A
Pedersen, K. L., Töllner, K., Feit, P. W., Erker, T., MacAulay, Nanna & Löscher, W., Jun 2016, In: Epilepsy & Behavior. 59, p. 42-49 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gβγ Signaling Regulates Aquaporin-2 Trafficking and Urinary Concentration
Olesen, Emma Tina Bisgaard, Poulsen, S. B., MacAulay, Nanna, Rieg, T. & Fenton, R. A., Apr 2016, In: F A S E B Journal. 30, S1Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The Vasopressin Type-2 Receptor and Prostaglandin Receptors EP2 and EP4 can Increase Aquaporin-2 Plasma Membrane Targeting Through a cAMP Independent Pathway
Olesen, Emma Tina Bisgaard, Moeller, H. B., Assentoft, M., MacAulay, Nanna & Fenton, R. A., 1 Nov 2016, In: American Journal of Physiology: Renal Physiology. 311, 5, p. F935-F944 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral influx of Na+ and Cl- as the osmotherapy-mediated rebound response in rats
Oernbo, E. K., Lykke, K., Steffensen, Annette Buur, Töllner, K., Kruuse, Christina Rostrup, Rath, Martin Fredensborg, Löscher, W. & MacAulay, Nanna, 2018, In: Fluids and Barriers of the CNS. 15, 14 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
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Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
Oernbo, E. K., Steffensen, Annette Buur, Khamesi, P. R., Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Vilhardt, Frederik, Gerkau, N. J., Tritsaris, Katerina, Simonsen, A. H., Lolansen, Sara Diana, Andreassen, Søren Norge, Hasselbalch, Steen, Zeuthen, Thomas, Rose, C. R., Kurtcuoglu, V. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 25 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural determinants underlying permeant discrimination of the Cx43 hemichannel
Nielsen, B. S., Zonta, F., Farkas, T., Litman, Thomas, Nielsen, Morten Schak & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 45, p. 16789-16803 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pannexin 1 activation and inhibition is permeant-selective
Nielsen, B. S., Toft-Bertelsen, Trine Lisberg, Lolansen, Sara Diana, Anderson, C. L., Nielsen, Morten Schak, Thompson, R. J. & MacAulay, Nanna, 2020, In: The Journal of Physiology. 598, 2, p. 361-379 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Connexin Hemichannels in Astrocytes: An Assessment of Controversies Regarding Their Functional Characteristics
Nielsen, B. S., Hansen, D. B., Ransom, B. R., Nielsen, Morten Schak & MacAulay, Nanna, Sep 2017, In: Neurochemical Research. 42, 9, p. 2537–2550 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Permeant-specific gating of connexin 30 hemichannels
Nielsen, B. S., Alstrom, J. S., Nicholson, B., Nielsen, Morten Schak & MacAulay, Nanna, 2017, In: Journal of Biological Chemistry. 292, 49, p. 19999-20009Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10786
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Managing Brain Extracellular K(+) during Neuronal Activity: The Physiological Role of the Na(+)/K(+)-ATPase Subunit Isoforms
Research output: Contribution to journal › Review › Research › peer-review
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Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
206
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Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Research output: Contribution to journal › Journal article › Research › peer-review
Published