Claus Juul Løland

Claus Juul Løland

Professor

ORCID: 0000-0002-1773-1446

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  1. Published

    An Engineered Lithocholate-Based Facial Amphiphile Stabilizes Membrane Proteins: Assessing the Impact of Detergent Customizability on Protein Stability

    Das, M., Du, Y., Mortensen, Jonas Sigurd, Bae, H. E., Byrne, B., Loland, Claus Juul, Kobilka, B. K. & Chae, P. S., 11 Jul 2018, In: Chemistry - A European Journal. 24, 39, p. 9860-9868 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Conformationally Preorganized Diastereomeric Norbornane-Based Maltosides for Membrane Protein Study: Implications of Detergent Kink for Micellar Properties

    Das, M., Du, Y., Ribeiro, O., Hariharan, P., Mortensen, Jonas Sigurd, Patra, D., Skiniotis, G., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., 2017, In: Journal of the American Chemical Society. 139, 8, p. 3072-3081

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Trehalose-cored amphiphiles for membrane protein stabilization: importance of the detergent micelle size in GPCR stability

    Das, M., Du, Y., Mortensen, Jonas Sigurd, Ramos, M., Ghani, L., Lee, H. J., Bae, H. E., Byrne, B., Guan, L., Loland, Claus Juul, Kobilka, B. K. & Chae, P. S., 2019, In: Organic & Biomolecular Chemistry. 17, 12, p. 3249-3257 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Rationally Engineered Tandem Facial Amphiphiles for Improved Membrane Protein Stabilization Efficacy

    Das, M., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Lee, H. S., Byrne, B., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2018, In: ChemBioChem. 19, 20, p. 2225-2232 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study

    Das, M., Mahler, F., Hariharan, P., Wang, H., Du, Y., Mortensen, Jonas Sigurd, Patallo, E. P., Ghani, L., Glück, D., Lee, H. J., Byrne, B., Loland, Claus Juul, Guan, L., Kobilka, B. K., Keller, S. & Chae, P. S., 2020, In: Journal of the American Chemical Society. 142, 51, p. 21382–21392 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region

    Das, M., Du, Y., Mortensen, Jonas Sigurd, Ribeiro, O., Hariharan, P., Guan, L., Loland, Claus Juul, Kobilka, B. K., Byrne, B. & Chae, P. S., 2017, In: Chemical Science. 2, p. 1169-1177 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Self-Assembly Behavior and Application of Terphenyl-Cored Trimaltosides for Membrane-Protein Studies: Impact of Detergent Hydrophobic Group Geometry on Protein Stability

    Ehsan, M., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Qu, Q., Ghani, L., Das, M., Grethen, A., Byrne, B., Skiniotis, G., Keller, S., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2019, In: Chemistry: A European Journal. 25, 49, p. 11545-11554

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Highly Branched Pentasaccharide-Bearing Amphiphiles for Membrane Protein Studies

    Ehsan, M., Du, Y., Scull, N. J., Tikhonova, E., Tarrasch, J., Mortensen, Jonas Sigurd, Loland, Claus Juul, Skiniotis, G., Guan, L., Byrne, B., Kobilka, B. K. & Chae, P. S., 23 Mar 2016, In: Journal of the American Chemical Society. 138, 11, p. 3789-3796 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    New penta-saccharide-bearing tripod amphiphiles for membrane protein structure studies

    Ehsan, M., Ghani, L., Du, Y., Hariharan, P., Mortensen, Jonas Sigurd, Ribeiro, O., Hu, H., Skiniotis, G., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., Oct 2017, In: Analyst. 142, 20, p. 3889-3898 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Self-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study

    Ehsan, M., Kumar, A., Mortensen, Jonas Sigurd, Du, Y., Hariharan, P., Kumar, K. K., Ha, B., Byrne, B., Guan, L., Kobilka, B. K., Loland, Claus Juul & Chae, P. S., 2019, In: Chemistry - An Asian Journal. 14, 11, p. 1926-1931 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Glyco-Steroidal Amphiphiles (GSAs) for Membrane Protein Structural Study

    Ehsan, M., Wang, H., Katsube, S., Munk, C. F., Du, Y., Youn, T., Yoon, S., Byrne, B., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2022, In: ChemBioChem. 23, 7, e202200027.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Steroid-based amphiphiles for membrane protein study: The importance of alkyl spacers for protein stability

    Ehsan, M., Das, M., Stern, V., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Byrne, B., Loland, Claus Juul, Kobilka, B. K., Guan, L. & Chae, P. S., 2018, In: ChemBioChem. 19, 13, p. 1433-1443 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Maltose-bis(hydroxymethyl)phenol (MBPs) and Maltose-tris(hydroxymethyl)phenol (MTPs) Amphiphiles for Membrane Protein Stability

    Ehsan, M., Wang, H., Cecchetti, C., Mortensen, Jonas Sigurd, Du, Y., Hariharan, P., Nygaard, Andreas, Lee, H. J., Ghani, L., Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Chae, P. S., 2021, In: ACS chemical biology. 16, 9, p. 1779–1790 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability

    Ehsan, M., Katsube, S., Cecchetti, C., Du, Y., Mortensen, Jonas Sigurd, Wang, H., Nygaard, Andreas, Ghani, L., Loland, Claus Juul, Kobilka, B. K., Byrne, B., Guan, L. & Chae, P. S., 2020, In: ACS chemical biology. 15, 6, p. 1697-1707 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Vitamin E-based glycoside amphiphiles for membrane protein structural studies

    Ehsan, M., Du, Y., Molist, I., Seven, A. B., Hariharan, P., Mortensen, Jonas Sigurd, Ghani, L., Loland, Claus Juul, Skiniotis, G., Guan, L., Byrne, B., Kobilka, B. K. & Chae, P. S., 2018, In: Organic and Biomolecular Chemistry. 16, 14, p. 2489-2498 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

    qrc243, qrc243, Gotfryd, K., Larsen, F. H., Mortensen, Jonas Sigurd, Geiger, M., van Rossum, B., Oschkinat, H., Gether, Ulrik, Teilum, Kaare & Loland, Claus Juul, 2017, In: eLife. 6, 9 p., e19314.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila

    Gericke, Oliver, Fowler, R., Heskes, A., Bayly, M., Semple, S., Ndi, C. P., Stærk, Dan, Loland, Claus Juul, Murphy, D. J., Buirchell, B. & Møller, Birger Lindberg, 2021, In: Plant Journal. 108, 2, p. 555-578

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites

    Gether, Ulrik, Norregaard, L. & Loland, Claus Juul, 2001, In: Life Sciences. 68 (19-20), p. 2187-2198

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance

    Ghani, L., Kim, S., Ehsan, M., Lan, B., Poulsen, I. H., Dev, C., Katsube, S., Byrne, B., Guan, L., Loland, Claus Juul, Liu, X., Im, W. & Chae, P. S., 2023, In: Chemical Science. 14, 45, 11 p., 13014.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Tris(hydroxymethyl)aminomethane Linker-Bearing Triazine-Based Triglucosides for Solubilization and Stabilization of Membrane Proteins

    Ghani, L., Zhang, X., Munk, C. F., Hariharan, P., Lan, B., Yun, H. S., Byrne, B., Guan, L., Loland, Claus Juul, Liu, X. & Chae, P. S., 2023, In: Bioconjugate Chemistry. 34, 4, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Foldable detergents for membrane protein study: Importance of detergent core flexibility in protein stabilization

    Ghani, L., Kim, S., Wang, H., Lee, H. S., Mortensen, Jonas Sigurd, Katsube, S., Du, Y., Sadaf, A., Byrne, B., Guan, L., Loland, Claus Juul, Kobilka, B. K., Im, W., Chae, P. S. & Ahmed, W., 2022, In: Chemistry: A European Journal. 28, 21, 9 p., e202200116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    1,3,5-Triazine-Cored Maltoside Amphiphiles for Membrane Protein Extraction and Stabilization

    Ghani, L., Munk, C. F., Zhang, X., Katsube, S., Du, Y., Cecchetti, C., Huang, W., Bae, H. E., Saouros, S., Ehsan, M., Guan, L., Liu, X., Loland, Claus Juul, Kobilka, B. K., Byrne, B. & Chae, P. S., 2019, In: Journal of the American Chemical Society. 141, 50, p. 19677-19687 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

    Gotfryd, K., Boesen, T., Mortensen, Jonas Sigurd, Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In: Nature Communications. 11, 1, 14 p., 1005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 14 Feb 2003, In: The Journal of Biological Chemistry. 278, 7, p. 4990-5000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter interanalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. Vol. 278 (7), p. 4990-5000

    Research output: Contribution to journal › Journal article › Research › peer-review

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