Claus Juul Løland

Claus Juul Løland

Professor

ORCID: 0000-0002-1773-1446

Publication year:
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1 - 25 out of 125Page size: 25
  1. 1999
  2. Published

    Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

    Loland, Claus Juul, Norregaard, L. & Gether, Ulrik, 1999, In: Journal of Biological Chemistry. 274, 52, p. 36928-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2000
  4. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J., Weinstein, H. & Gether, Ulrik, 26 Dec 2000, In: Biochemistry. 39, 51, p. 15836-15846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2001
  6. Published

    Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites

    Gether, Ulrik, Norregaard, L. & Loland, Claus Juul, 2001, In: Life Sciences. 68 (19-20), p. 2187-2198

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Engineered Zn(2+)switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

    MacAulay, Nanna, Bendahan, A., Loland, Claus Juul, Zeuthen, Thomas, Kanner, B. I. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276, p. 40476-40485

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J. A., Weinstein, H. & Gether, Ulrik, 2001, In: Biochemistry. 39 (51), p. 15836-15846

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2002
  10. Published

    Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2003
  13. Published

    Evidence for distinct sodium-, dopamine-, cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. Vol. 278 (33), p. 30587-96

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter interanalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. Vol. 278 (7), p. 4990-5000

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In: European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 14 Feb 2003, In: The Journal of Biological Chemistry. 278, 7, p. 4990-5000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 15 Aug 2003, In: The Journal of Biological Chemistry. 278, 33, p. 30587-96 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2004
  20. Published

    Insights from endogenous and engineered Zn2+-binding sites in monoanine transporters

    Loland, Claus Juul & Gether, Ulrik, 2004, Molecular Neuropharmacology: Strategies and Methods. p. 191-213

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  21. Published

    Intracellular residues in the dopamine transporter critical for conformational isomerization, molecular gating and cocaine binding

    Loland, Claus Juul, Granas, C., Javitc, J. & Gether, Ulrik, 2004, In: Journal of Biological Chemistry. Vol. 279, no. 5, p. 3228-38

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ doamin interactions

    Bjerggaard, C., Fog, J. U., Hastrup-Nielsen, H., Madsen, K., Loland, Claus Juul, Javitch, J. & Gether, Ulrik, 2004, In: Journal of Neuroscience. Vol. 24, no. 31, p. 7024-36

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding

    Loland, Claus Juul, Grånäs, C., Javitch, J. A. & Gether, Ulrik, 30 Jan 2004, In: The Journal of Biological Chemistry. 279, 5, p. 3228-38 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2005
  25. Published

    Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8

    Kniazeff, J., Loland, Claus Juul, Goldberg, N., Quick, M., Das, S., Sitte, H. H., Javitch, J. A. & Gether, Ulrik, Nov 2005, In: Neuropharmacology. 49, 6, p. 715-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2006
  28. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In: Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2007
  30. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In: Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2008
  32. Published

    An intracellular interaction network regulates conformational transitions in the dopamine transporter.

    Kniazeff, J., Shi, L., Loland, Claus Juul, Javitch, J. A., Weinstein, H. & Gether, Ulrik, 2008, In: Journal of Biological Chemistry. 283, 25, p. 17691-701 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The binding sites for cocaine and dopamine in the dopamine transporter overlap.

    Beuming, T., Kniazeff, J., Bergmann, M. L., Shi, L., Gracia, L., Raniszewska, K., Newman, A. H., Javitch, J. A., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 2008, In: Nature Neuroscience. 11, 7, p. 780-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. 2009
  35. Published

    Neurotransmitter transporters: structure and function

    Loland, Claus Juul & Gether, Ulrik, 2009, Texbook of Drug Design and Discovery. Madsen, U., Krogsgaard-Larsen, P. & Stromgaard, K. (eds.). 4 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  36. 2010
  37. Published

    Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Chandra, R., Goren, M. A., Kruse, A. C., Nurva, S., Loland, Claus Juul, Pierre, Y., Drew, D., Popot, J., Picot, D., Fox, B. G., Guan, L., Gether, Ulrik, Byrne, B., Kobilka, B. & Gellman, S. H., 2010, In: Nature Methods. 7, p. 1003-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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