Claus Juul Løland

Claus Juul Løland

Professor


  1. Published

    The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation

    Abramyan, A. M., Stolzenberg, S., Li, Z., Loland, Claus Juul, Noe, F. & Shi, L., 2017, In: A C S Chemical Neuroscience. 8, 8, p. 1735-1746 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Deoxycholate-Based Glycosides (DCGs) for Membrane Protein Stabilisation

    Bae, H. E., Gotfryd, K., Thomas, J., Hussain, H., Ehsan, M., Go, J., Loland, Claus Juul, Byrne, B. & Chae, P. S., 2015, In: ChemBioChem. 16, 10, p. 1454–1459 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  3. Published

    Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation

    Bae, H. E., Mortensen, Jonas Sigurd, Ribeiro, O., Du, Y., Ehsan, M., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Chae, P. S., 4 Oct 2016, In: Chemical communications (Cambridge, England). 52, 81, p. 12104-12107 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability

    Bae, H. E., Du, Y., Hariharan, P., Mortensen, Jonas Sigurd, Kumar, K. K., Ha, B., Das, M., Lee, H. S., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2019, In: Chemical Science. 10, 4, p. 1107-1116

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization

    Bae, H. E., Cecchetti, C., Du, Y., Katsube, S., Mortensen, Jonas Sigurd, Huang, W., Rehan, S., Lee, H. J., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., 2020, In: Acta Biomaterialia. 112, p. 250-261 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Design and synthesis of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile (citalopram) analogues as novel probes for the serotonin transporter S1 and S2 binding sites

    Banala, A. K., Zhang, P., Plenge, P., Cyriac, G., Kopajtic, T., Katz, J. L., Loland, Claus Juul & Newman, A. H., 12 Dec 2013, In: Journal of Medicinal Chemistry. 56, 23, p. 9709-24 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The binding sites for cocaine and dopamine in the dopamine transporter overlap.

    Beuming, T., Kniazeff, J., Bergmann, M. L., Shi, L., Gracia, L., Raniszewska, K., Newman, A. H., Javitch, J. A., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 2008, In: Nature Neuroscience. 11, 7, p. 780-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter: Sodium Symporter

    Billesbolle, C. B., Kruger, M. B., Shi, L., Quick, M., Li, Z., Stolzenberg, S., Kniazeff, J., Gotfryd, K., Mortensen, Jonas Sigurd, Javitch, J. A., Weinstein, H., Loland, Claus Juul & Gether, Ulrik, 30 Oct 2015, In: Journal of Biological Chemistry. 290, 44, p. 26725-26738 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter

    Billesbølle, C. B., Mortensen, Jonas Sigurd, Sohail, A., Schmidt, S. G., Shi, L., Sitte, H. H., Gether, Ulrik & Loland, Claus Juul, 28 Sep 2016, In: Nature Communications. 7, 12 p., 12755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ doamin interactions

    Bjerggaard, C., Fog, J. U., Hastrup-Nielsen, H., Madsen, K., Loland, Claus Juul, Javitch, J. & Gether, Ulrik, 2004, In: Journal of Neuroscience. Vol. 24, no. 31, p. 7024-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Use of dihydro-isobenzofuran in combination with serotonin reuptake inhibitors for CNS disease e.g. depression, anxiety, bipolar disorder, obsessive compulsory disorder

    Bøgesø, K. P., Juhl, K., Zhong, H. & Loland, Claus Juul, 2013, IPC No. C07D-307/79, Patent No. WO2013110313-A1, Priority date 21 Aug 2013, Priority No. WOEP050952

    Research output: Patent

  12. Published

    Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT

    Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors

    Cao, J., Slack, R. D., Bakare, O. M., Burzynski, C., Rais, R., Slusher, B. S., Kopajtic, T., Bonifazi, A., Ellenberger, M. P., Yano, H., He, Y., Bi, G., Xi, Z., Loland, Claus Juul & Newman, A. H., 8 Dec 2016, In: Journal of Medicinal Chemistry. 59, 23, p. 10676-10691 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Novel Tripod Amphiphiles for Membrane Protein Analysis

    Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Correction to "tandem facial amphiphiles for membrane protein stabilization"

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In: Journal of the American Chemical Society. 135, 34, p. 12922 1 p.

    Research output: Contribution to journalJournal articleResearch

  17. Published

    Tandem Facial Amphiphiles for Membrane Protein Stabilization

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Chandra, R., Goren, M. A., Kruse, A. C., Nurva, S., Loland, Claus Juul, Pierre, Y., Drew, D., Popot, J., Picot, D., Fox, B. G., Guan, L., Gether, Ulrik, Byrne, B., Kobilka, B. & Gellman, S. H., 2010, In: Nature Methods. 7, p. 1003-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

    Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In: Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In: Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Preface: Special issue on neurotransmitter transporters

    Chaudhry, F. A., Loland, Claus Juul, Ortega, A. & Schousboe, Arne, 2019, In: Neuropharmacology. 161, 1 p., 107859.

    Research output: Contribution to journalEditorialResearchpeer-review

  22. Published

    Mesitylene-Cored Glucoside Amphiphiles (MGAs) for Membrane Protein Studies: Importance of Alkyl Chain Density in Detergent Efficacy

    Cho, K. H., Ribeiro, O., Du, Y., Tikhonova, E., Mortensen, Jonas Sigurd, Markham, K., Hariharan, P., Loland, Claus Juul, Guan, L., Kobilka, B., Byrne, B. & Chae, P. S., 23 Dec 2016, In: Chemistry: A European Journal. 22, 52, p. 18833–18839

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation

    Cho, K. H., Du, Y., Scull, N. J., Hariharan, P., Gotfryd, K., Loland, Claus Juul, Guan, L., Byrne, B., Kobilka, B. K. & Chae, P. S., 2015, In: Chemistry: A European Journal. 21, 28, p. 10008–10013 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  24. Published

    Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study

    Cho, K. H., Husri, M., Amin, A., Gotfryd, K., Lee, H. J., Go, J., Kim, J. W., Loland, Claus Juul, Guan, L., Byrne, B. & Chae, P. S., 2015, In: The Analyst. 140, 9, p. 3157-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length

    Cho, K. H., Hariharan, P., Mortensen, Jonas Sigurd, Du, Y., Nielsen, A. K., Byrne, B., Kobilka, B. K., Loland, Claus Juul, Guan, L. & Chae, P. S., 14 Dec 2016, In: ChemBioChem. 17, 24, p. 2334–2339

    Research output: Contribution to journalJournal articleResearchpeer-review

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