Ulrik Gether

Ulrik Gether

Head of Department, Professor

ORCID: 0000-0002-0020-3807

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  1. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding

    Loland, Claus Juul, Grånäs, C., Javitch, J. A. & Gether, Ulrik, 30 Jan 2004, In: The Journal of Biological Chemistry. 279, 5, p. 3228-38 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

    Lu, T. T., Lao, O., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Nielsen, F., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A. & 14 others, Gether, Ulrik, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Ruether, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Kayser, M. & Krawczak, M., 2009, In: European Journal of Human Genetics. 17, 7, p. 967-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

    Lund, Viktor Karlovich, Lycas, M. D., Schack, A., Andersen, Rita Chan, Gether, Ulrik & Kjærulff, Ole, 2021, In: Cell Reports. 35, 2, 26 p., 108973.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity

    Lycas, M. D., Ejdrup, Aske Lykke, Sørensen, Andreas Toft, Haahr, N. O., Jørgensen, Søren Heide, Guthrie, D. A., Støier, J. F., Werner, C., Newman, A. H., Sauer, M., Herborg, Freja & Gether, Ulrik, 2022, In: Cell Reports. 40, 13, 27 p., 111431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Neurotransmitter Transporters: Structure, Function, and Drug Binding

    Loland, Claus Juul & Gether, Ulrik, 2017, Textbook of Drug Design and Discovery. Stromgaard, K., Krogsgaard-Larsen, P. & Madsen, U. (eds.). 5 ed. Boca Raton: CRC Press, p. 233-248 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  8. Published

    Neurotransmitter transporters: structure and function

    Loland, Claus Juul & Gether, Ulrik, 2009, Texbook of Drug Design and Discovery. Madsen, U., Krogsgaard-Larsen, P. & Stromgaard, K. (eds.). 4 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  9. Published

    Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

    Loland, Claus Juul, Norregaard, L. & Gether, Ulrik, 1999, In: Journal of Biological Chemistry. 274, 52, p. 36928-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In: Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Intracellular residues in the dopamine transporter critical for conformational isomerization, molecular gating and cocaine binding

    Loland, Claus Juul, Granas, C., Javitc, J. & Gether, Ulrik, 2004, In: Journal of Biological Chemistry. Vol. 279, no. 5, p. 3228-38

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Insights from endogenous and engineered Zn2+-binding sites in monoanine transporters

    Loland, Claus Juul & Gether, Ulrik, 2004, Molecular Neuropharmacology: Strategies and Methods. p. 191-213

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  13. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In: European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In: Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1

    MacAulay, Nanna, Zeuthen, Thomas & Gether, Ulrik, 15 Oct 2002, In: Journal of Physiology. 544, Pt 2, p. 447-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1.

    MacAulay, Nanna, Meinild, A., Zeuthen, Thomas & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. 278, 31, p. 28771-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Conformational basis for the Li+- induced leak current in the rat ¿- aminobutyric acid (GABA) transporter- 1

    MacAulay, Nanna, Zeuthen, Thomas & Gether, Ulrik, 2002, In: Journal of Physiology. 544, 2, p. 447-458

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Passive water and urea permeability of a human Na(+)-glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klærke, Dan Arne & Zeuthen, Thomas, 2002, In: Journal of Physiology. 542, 3, p. 817-828 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Water transport by the human Na+-coupled glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klaerke, D. A. & Zeuthen, T., 2001, In: Journal of Physiology. 530 (Pt 3), p. 367-378

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Engineered Zn(2+)switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

    MacAulay, Nanna, Bendahan, A., Loland, Claus Juul, Zeuthen, Thomas, Kanner, B. I. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276, p. 40476-40485

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Membrane localization is critical for activation of the PICK1BAR domain

    Madsen, K. L., Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., mmendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In: Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-1343 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Molecular determinants for the complex binding specifity of the PDZ domain in PICK1

    Madsen, K. L., Beuming, T., Niv, M. Y., Chang, C. W., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In: Journal of Biological Chemistry. Vol. 280, no. 21, p. 20539-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Molecular determinants for the complex binding specificity of the PDZ domain in PICK1

    Madsen, Kenneth Lindegaard, Beuming, T., Niv, M. Y., Chang, C., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In: Journal of Biological Chemistry. 280, 21, p. 20539-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Membrane localization is critical for activation of the PICK1 BAR domain

    Madsen, Kenneth Lindegaard, Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., Ammendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In: Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-43 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway

    Madsen, Kenneth Lindegaard, Thorsen, T. S., Rahbek-Clemmensen, T., Eriksen, J. M. & Gether, Ulrik, 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12293-308 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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