Ulrik Gether

Ulrik Gether

Head of Department, Professor


  1. Published

    Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

    Hansen, F. H., Skjørringe, T., Yasmeen, S., Arends, N. V., Sahai, M. A., Erreger, K., Andreassen, T. F., Holy, M., Hamilton, P. J., Neergheen, V., Karlsborg, M., Newman, A. H., Pope, S., Heales, S. J. R., Friberg, L., Law, I., Pinborg, L. H., Sitte, H. H., Loland, C., Shi, L. & 5 others, Weinstein, H., Galli, A., Hjermind, L. E., Møller, L. B. & Gether, Ulrik, 1 Jul 2014, In: The Journal of Clinical Investigation. 124, 7, p. 3107-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    How curved membranes recruit amphipathic helices and protein anchoring motifs

    Hatzakis, Nikos, Bhatia, V. K., Larsen, J., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A. H., Castillo Leon, J. J., Gether, Ulrik, Hedegård, Per & Stamou, Dimitrios, 2009, In: Nature Chemical Biology. 5, 11, p. 835-841 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2

    Henriksen, U. B., Fog, J. U., Litman, Thomas & Gether, Ulrik, 4 Nov 2005, In: Journal of Biological Chemistry. 280, 44, p. 36926-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2

    Henriksen, U. B., Gether, Ulrik & Litman, Thomas, 1 Apr 2005, In: Journal of Cell Science. 118, Pt 7, p. 1417-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes

    Herborg, Freja, Andreassen, T. F., Berlin, F., Loland, Claus Juul & Gether, Ulrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7250-7262 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease

    Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, Galli, A., Hjermind, L. E., Gether, Ulrik & IPSYCH Researchers, I. R., 2021, In: JCI insight. 6, 18, 21 p., 151496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1

    Jensen, Rasmus Herlo Beenfeldt, Lund, Viktor Karlovich, Lycas, M. D., Jansen, A. M., Khelashvili, G., Andersen, Rita Chan, Bhatia, V., Pedersen, T. S., Albornoz, P. B. C., Johner, N., Ammendrup-Johnsen, I., Christensen, N. R., qrc243, qrc243, Stoklund, M., Larsen, J. B., Weinstein, H., Kjærulff, Ole, Stamou, Dimitrios, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2018, In: Cell Reports. 23, 7, p. 2056-2069 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Theory of visual attention (TVA) applied to rats performing the 5-choice serial reaction time task: differential effects of dopaminergic and noradrenergic manipulations

    Hervig, M. E. S., Toschi, C., Petersen, Anders, Vangkilde, Signe, Gether, Ulrik & Robbins, T. W., 2023, In: Psychopharmacology. 240, p. 41-58 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance

    Holst, Birgitte, Madsen, Kenneth Lindegaard, Jansen, A. M., Jin, C., Rickhag, Karl Mattias, Lund, Viktor Karlovich, Jensen, M., Bhatia, V., Sørensen, G., Madsen, A. N., Xue, Z., Møller, S. K., Woldbye, David Paul Drucker, Qvortrup, Klaus, Huganir, R., Stamou, Dimitrios, Kjærulff, Ole & Gether, Ulrik, Apr 2013, In: P L o S Biology (Online). 11, 4, p. 1-25 25 p., e1001542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

    Jacobsen, S. E., Gether, Ulrik & Bräuner, Hans, 2017, In: Scientific Reports. 7, 14 p., 46355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The GPRC6A Receptor displays Constitutive Internalization and Sorting to the Slow Recycling Pathway

    Jacobsen, S. E., Ammendrup-Johnsen, I., Jansen, A. M., Gether, Ulrik, Madsen, Kenneth Lindegaard & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 17, p. 6910-6926

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders

    Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In: European Journal of Psychiatry. 22, 3, p. 161-172 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    PICK1 expression in the Drosophila central nervous system primarily occurs in the neuroendocrine system

    Jansen, A. M., Nässel, D. R., Madsen, Kenneth Lindegaard, Jung, A. G., Gether, Ulrik & Kjærulff, Ole, 2009, In: Journal of Comparative Neurology. 517, 3, p. 313-32 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization

    Jayanthi, L. D., Annamalai, B., Samuvel, D. J., Gether, Ulrik & Ramamoorthy, S., 2006, In: Journal of Biological Chemistry. 281, 33, p. 23326-40 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

    Jensen, A. D., Guarnieri, F., Rasmussen, Søren Gøgsig Faarup, Asmar, F., Ballesteros, J. A. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (12), p. 9279-9290

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The binding sites for benztropines and dopamine in the dopamine transporter overlap

    Jensen, H. B., Larsen, M. A. B., Mazier, S., Beuming, T., Weinstein, H., Shi, L., Loland, Claus Juul & Gether, Ulrik, 1 Jan 2011, In: Neuropharmacology. 60, 1, p. 182-90 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake

    Jensen, Kathrine Louise, Runegaard, A. H., Weikop, Pia, Gether, Ulrik & Rickhag, Karl Mattias, Sep 2017, In: Journal of Visualized Experiments. 127, 10 p., e56093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

    Jensen, Kathrine Louise, Sørensen, G., Dencker, D., Owens, W. A., Rahbek-Clemmensen, T., Brett Lever, M., Runegaard, A. H., Riis Christensen, N., Weikop, Pia, Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth Lindegaard, Daws, L., Gether, Ulrik & Rickhag, Karl Mattias, 2018, In: eNeuro. 5, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent

    Jensen, M. E., Galli, A., Thomsen, M., Jensen, Kathrine Louise, Thomsen, G. K., Klausen, M. K., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul, Owens, A., Robertson, S., Daws, L., Zanella, D., Gether, Ulrik, Knudsen, Gitte Moos & Fink-Jensen, Anders, 2020, In: Neurochemistry International. 138, 9 p., 104772.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Assessing adrenergic receptor conformation using chemically reactive fluorescent probes

    Jensen Dam, A. & Gether, Ulrik, 2000, Methods in Molecular Biology, vol.126: Adrenergic Receptors Protocols. Totowa, NJ: Humana Press, p. 345-359

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research

    Jørgensen, Søren Heide, Fitzpatrick, C. M., Gether, Ulrik, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, Nov 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Behavioral encoding across timescales by region-specific dopamine dynamics

    Jørgensen, Søren Heide, Ejdrup, Aske Lykke, Lycas, M. D., Posselt, Leonie Pauline, Madsen, Kenneth Lindegaard, Tian, L., Dreyer, J. K., Herborg, Freja, Sørensen, Andreas Toft & Gether, Ulrik, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, 10 p., e2215230120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Serotonin-induced down-regulation of cell surface serotonin transporter

    Jørgensen, T. N., Christensen, P. M. & Gether, Ulrik, Jul 2014, In: Neurochemistry International. 73, p. 107-12 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In: Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering

    Karlsen, M. L., Thorsen, T. S., Johner, N., Ammendrup-Johnsen, I., qrc243, qrc243, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In: Structure. 23, 7, p. 1258-1270 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11898