Double-label and conventional deoxyglucose methods: a practical guide for the user.
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Double-label and conventional deoxyglucose methods: a practical guide for the user. / Redies, C; Gjedde, A.
In: Cerebrovascular and Brain Metabolism Reviews, Vol. 1, No. 4, 1989, p. 319-67.Research output: Contribution to journal › Review › Research
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TY - JOUR
T1 - Double-label and conventional deoxyglucose methods: a practical guide for the user.
AU - Redies, C
AU - Gjedde, A
PY - 1989
Y1 - 1989
N2 - The autoradiographic deoxyglucose method is widely used to map functional activity in mammalian brain. Whereas the method is simple to use, the underlying kinetic model is complex. This paper reviews the deoxyglucose kinetic model and the relevant implications for the user who does not have extensive knowledge of tracer kinetics. In generally understandable terms, single-label and double-label deoxyglucose approaches are discussed. Experimental procedures are described in detail. The calculations required for qualitative and quantitative experiments are explained. The deoxyglucose method is compared to other methods that map functional activity in mammalian brain.
AB - The autoradiographic deoxyglucose method is widely used to map functional activity in mammalian brain. Whereas the method is simple to use, the underlying kinetic model is complex. This paper reviews the deoxyglucose kinetic model and the relevant implications for the user who does not have extensive knowledge of tracer kinetics. In generally understandable terms, single-label and double-label deoxyglucose approaches are discussed. Experimental procedures are described in detail. The calculations required for qualitative and quantitative experiments are explained. The deoxyglucose method is compared to other methods that map functional activity in mammalian brain.
M3 - Review
C2 - 2701657
VL - 1
SP - 319
EP - 367
JO - Cerebrovascular and Brain Metabolism Reviews
JF - Cerebrovascular and Brain Metabolism Reviews
SN - 1040-8827
IS - 4
ER -
ID: 14943159