Trine Lisberg Toft
Assistant Professor, Associate Professor
Molecular Neuroscience
Blegdamsvej 3
2200 København N
Member of:
- 2013
- Published
Developmental and Diurnal Expression of the Synaptosomal-Associated Protein 25 (Snap25) in the Rat Pineal Gland
Karlsen, A. S., Rath, Martin Fredensborg, Rohde, K., Toft-Bertelsen, Trine Lisberg & Møller, Morten, Jun 2013, In: Neurochemical Research. 38, 6, p. 1219-1228 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The SNARE protein vti1a functions in dense-core vesicle biogenesis
Walter, Alexander Matthias, Kurps, J., de Wit, H., Schöning, S., Toft-Bertelsen, Trine Lisberg, Lauks, J., Ziomkiewicz, I., Weiss, A. N., Schulz, Alexander, Fischer von Mollard, G., Verhage, M. & Sørensen, Jakob Balslev, 5 Jun 2014, In: E M B O Journal. 33, p. 1681-1697 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23
Weber, J. P., Toft-Bertelsen, Trine Lisberg, Mohrmann, R., Delgado-Martinez, I. & Sørensen, Jakob Balslev, 2014, In: PloS one. 9, 11, p. 1-22 22 p., e114033.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis
Landegren, N., Pourmousa Lindberg, M., Skov, J., Hallgren, Å., Eriksson, D., Lisberg Toft-Bertelsen, T., MacAulay, N., Hagforsen, E., Räisänen-Sokolowski, A., Saha, H., Nilsson, T., Nordmark, G., Ohlsson, S., Gustafsson, J., Husebye, E. S., Larsson, E., Anderson, M. S., Perheentupa, J., Rorsman, F., Fenton, R. A. & 1 others, , Oct 2016, In: Journal of the American Society of Nephrology:JASN. 27, 10, p. 3220-3228Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters
Toft-Bertelsen, Trine Lisberg, Ziomkiewicz, I., Houy, S., da Silva Pinheiro, P. C. & Sørensen, Jakob Balslev, 1 Nov 2016, In: Molecular Biology of the Cell. 27, 21, p. 3329-3341 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor
Toft-Bertelsen, Trine Lisberg, Križaj, D. & MacAulay, Nanna, 1 Jun 2017, In: The Journal of Physiology. 595, 11, p. 3287-3302 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor
Toft-Bertelsen, Trine Lisberg, Križaj, D. & MacAulay, Nanna, 2017, In: Journal of Physiology. 595, 11, p. 3287-3302 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance
Berland, S., Toft-Bertelsen, Trine Lisberg, Aukrust, I., Byska, J., Vaudel, M., Bindoff, L. A., MacAulay, Nanna & Houge, G., 2018, In: Cold Spring Harbor molecular case studies. 4, 1, 10 p., a002303.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy
Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Lykke, K., Toft-Bertelsen, Trine Lisberg, Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, Nanna, Kaila, K. & Löscher, W., 2018, In: Neuropharmacology. 143, p. 186-204 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Corrigendum to “Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's antiseizure efficacy” [Neuropharmacology 143 (2018) 186–204](S0028390818306774)(10.1016/j.neuropharm.2018.09.025)
Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Hansen, Kasper Lykke, Toft-Bertelsen, Trine Lisberg, Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, Nanna, Kaila, K. & Löscher, W., Dec 2018, In: Neuropharmacology. 143, p. 349-350 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Sensing and regulation of cell volume - we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?
Toft-Bertelsen, Trine Lisberg, Larsen, B. R. & MacAulay, Nanna, 2018, In: Channels (Austin). 12, 1, p. 100-108Research output: Contribution to journal › Review › Research › peer-review
- 2019
- Published
Evaluating the involvement of cerebral microvascular endothelial Na+/K+-ATPase and Na+-K+-2Cl- co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration
Lykke, K., Assentoft, M., Hørlyck, S., Helms, H. C. C., Stoica, A., Toft-Bertelsen, Trine Lisberg, Tritsaris, Katerina, Vilhardt, Frederik, Larsen, Birger Brodin & MacAulay, Nanna, 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 3, p. 497-512Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type-specific and mediated by an N-terminal volume-sensing domain
Toft-Bertelsen, Trine Lisberg, Yarishkin, O., Redmon, S., Phuong, T. T. T., Krizaj, D. & MacAulay, Nanna, 2019, In: Journal of Biological Chemistry. 294, 48, p. 18421-18434 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Pannexin 1 activation and inhibition is permeant-selective
Nielsen, B. S., Toft-Bertelsen, Trine Lisberg, Lolansen, Sara Diana, Anderson, C. L., Nielsen, Morten Schak, Thompson, R. J. & MacAulay, Nanna, 2020, In: The Journal of Physiology. 598, 2, p. 361-379 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor
Toft-Bertelsen, Trine Lisberg, Larsen, B. R., Christensen, S. K., Khandelia, H., Waagepetersen, Helle S. & MacAulay, Nanna, 2020, In: Glia. 69, 1, p. 28-41 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission
Wierda, K. D. B., Toft-Bertelsen, Trine Lisberg, Gøtzsche, C. R., Pedersen, E., Korshunova, Irina, Nielsen, J., Bang, M. L., Kønig, A. B., Owczarek, S., Gjørlund, M. D., Schupp, M., Bock, E. & Sørensen, Jakob Balslev, 2020, In: Scientific Reports. 10, 1, 15 p., 18041.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension
Lakk, M., Hoffmann, G. F., Gorusupudi, A., Enyong, E., Lin, A., Bernstein, P. S., Toft-Bertelsen, Trine Lisberg, MacAulay, Nanna, Elliott, M. H. & Krizaj, D., 2021, In: Journal of Lipid Research. 62, 15 p., 100145.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRPing on Cell Swelling-TRPV4 Senses It
Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Frontiers in Immunology. 12, 9 p., 730982.Research output: Contribution to journal › Review › Research › peer-review
- Published
TRPing to the Point of Clarity: Understanding the Function of the Complex TRPV4 Ion Channel
Toft-Bertelsen, Trine Lisberg & MacAulay, Nanna, 2021, In: Cells. 10, 1, 16 p., 165.Research output: Contribution to journal › Review › Research › peer-review
- Published
Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro
Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Tzortzini, E., Xue, K., Giller, K., Becker, S., Mujezinovic, A., Bentzen, Bo Hjorth, Andreas, L. B., Kolocouris, A., Kledal, T. N. & Rosenkilde, Mette, 2021, In: Communications Biology. 4, 10 p., 1347.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus
Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Villadsen, René & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetazolamide modulates intracranial pressure directly by its action on the cerebrospinal fluid secretion apparatus
Barbuskaite, Dagne, Ørnbo, E. K., Wardman, Jonathan Henry, Toft-Bertelsen, Trine Lisberg, Conti, E., Andreassen, Søren Norge, Gerkau, N. J., Rose, C. R. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, p. 53 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters
Lolansen, Sara Diana, Rostgaard, Nina, Barbuskaite, Dagne, Capion, T., Olsen, M. H., Norager, N. H., Vilhardt, Frederik, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Ye, F., Juhler, Marianne, Keep, R. F. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 62.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
Oernbo, E. K., Steffensen, Annette Buur, Khamesi, P. R., Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Vilhardt, Frederik, Gerkau, N. J., Tritsaris, Katerina, Simonsen, A. H., Lolansen, Sara Diana, Andreassen, Søren Norge, Hasselbalch, Steen, Zeuthen, Thomas, Rose, C. R., Kurtcuoglu, V. & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 25 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viroporiners potentiale som lægemiddeltargets med fokus på SARS-CoV-2
Sund, J. D., Bollerup, S., Glamann, J. B., Vinten, C. A., Jensen, L. R., Toft-Bertelsen, Trine Lisberg, Bentzen, Bo Hjorth, Kledal, T. N., Weis, Nina & Rosenkilde, M., 13 Jun 2022, In: Ugeskrift for Laeger. 184, 24, 8 p., V02220103.Research output: Contribution to journal › Review › Research › peer-review
- Published
Reply to: How Many SARS-CoV-2 "Viroporins" Are Really Ion Channels? [Inkl. Correction]
Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Landbrug, A., Mujezinovic, A., Bentzen, Bo Hjorth, Kledal, T. N. & Rosenkilde, Mette, 2022, In: Communications Biology . 5, 1, 1 p., 860.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1
Toft-Bertelsen, Trine Lisberg, Barbuskaite, Dagne, Heerfordt, E. K., Lolansen, Sara Diana, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Rath, Martin Fredensborg, Juhler, Marianne & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 17 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion
Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2023
- Published
Dual function of the choroid plexus: Cerebrospinal fluid production and control of brain ion homeostasis
MacAulay, Nanna & Toft-Bertelsen, Trine Lisberg, 2023, In: Cell Calcium. 116, 9 p., 102797.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct Cerebrospinal Fluid Lipid Signature in Patients with Subarachnoid Hemorrhage-Induced Hydrocephalus
Toft-Bertelsen, Trine Lisberg, Andreassen, Søren Norge, Rostgaard, Nina, Olsen, M. H., Norager, N. H., Capion, T., Juhler, Marianne & MacAulay, Nanna, 2023, In: Biomedicines. 11, 9, 14 p., 2360.Research output: Contribution to journal › Journal article › Research › peer-review
- 2024
- Published
Toward New AQP4 Inhibitors: ORI-TRN-002
Thormann, M., Traube, N., Yehia, N., Koestler, R., Galabova, G., MacAulay, Nanna & Toft-Bertelsen, Trine Lisberg, 2024, In: International Journal of Molecular Sciences. 25, 2, 11 p., 924.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CSF hyperdynamics in rats mimicking the obesity and androgen excess characteristic of patients with idiopathic intracranial hypertension
Wardman, Jonathan Henry, Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Jensen, Mette Nyholm, Wilhjelm, J. E., Styrishave, Bjarne, Hamann, Steffen, Heegaard, Steffen, Sinclair, A. J. & MacAulay, Nanna, 2024, In: Fluids and Barriers of the CNS. 21, 1, 20 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetazolamide and topiramate lower intracranial pressure through differential mechanisms: The effect of acute and chronic administration
Westgate, C. S. J., Kamp-Jensen, C., Israelsen, I. M. E., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C. A., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rigmor Højland & Eftekhari, S., 2024, In: British Journal of Pharmacology. 181, 1, p. 70-86Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9932742
Most downloads
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203
downloads
Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
112
downloads
Sensing and regulation of cell volume - we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?
Research output: Contribution to journal › Review › Research › peer-review
Published -
89
downloads
A de novo Ser111Thr variant in aquaporin-4 in a patient with intellectual disability, transient signs of brain ischemia, transient cardiac hypertrophy, and progressive gait disturbance
Research output: Contribution to journal › Journal article › Research › peer-review
Published