Søren Gøgsig Faarup Rasmussen

Søren Gøgsig Faarup Rasmussen

Associate Professor

ORCID: 0000-0002-1853-1841

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  1. Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor

    Zocher, M., Zhang, C., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. K. & Müller, D. J., 11 Dec 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 50, p. E3463–E3472

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex

    Yao, X. J., Vélez Ruiz, G., Whorton, M. R., Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Deupi, X., Sunahara, R. K. & Kobilka, B., 9 Jun 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 23, p. 9501-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The two-domain elevator-type mechanism of zinc-transporting ZIP proteins

    Wiuf, A., Steffen, Jonas Hyld, Becares, E. R., Gronberg, C., Mahato, D. R., Rasmussen, Søren Gøgsig Faarup, Andersson, M., Croll, T., Gotfryd, K. & Gourdon, Pontus Emanuel, 2022, In: Science Advances. 8, 28, 13 p., 4331.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

    Whorton, M. R., Bokoch, M. P., Rasmussen, Søren Gøgsig Faarup, Huang, B., Zare, R. N., Kobilka, B. & Sunahara, R. K., 1 May 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7682-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex

    Westfield, G. H., Rasmussen, Søren Gøgsig Faarup, Su, M., Dutta, S., DeVree, B. T., Chung, K. Y., Calinski, D., Velez-Ruiz, G., Oleskie, A. N., Pardon, E., Chae, P. S., Liu, T., Li, S., Woods, V. L., Steyaert, J., Kobilka, B. K., Sunahara, R. K. & Skiniotis, G., 20 Sep 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 38, p. 16086-91 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Crystal Structures of the ß2-Adrenergic Receptor

    Weis, W. I., Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & et. al, E. A., 2009, From Molecules to Medicines, Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism. Springer, p. 217-230 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  7. Published

    Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs

    Walsh, S. M., Mathiasen, Signe, Christensen, S. M., Fay, J. F., King, C., Provasi, D., Borrero, E., Rasmussen, Søren Gøgsig Faarup, Fung, J. J., Filizola, M., Hristova, K., Kobilka, B., Farrens, D. L. & Stamou, Dimitrios, 2018, In: Biophysical Journal. 115, 2, p. 300-312 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level

    Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  9. Published

    Probing Activation and Conformational Dynamics of the Vesicle-Reconstituted β2 Adrenergic Receptor at the Single-Molecule Level

    Tutkus, M., Lundgaard, C. V., Veshaguri, S., Tønnesen, A., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2024, In: Journal of Physical Chemistry B. 128, 9, p. 2124–2133 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies

    Staus, D. P., Wingler, L. M., Strachan, R. T., Rasmussen, Søren Gøgsig Faarup, Pardon, E., Ahn, S., Steyaert, J., Kobilka, B. K. & Lefkowitz, R. J., Mar 2014, In: Molecular Pharmacology. 85, 3, p. 472-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum

    Selao, T. T., Branca, R., Chae, P. S., Lehtiö, J., Gellman, S. H., Rasmussen, Søren Gøgsig Faarup, Nordlund, S. & Norén, A., 3 Jun 2011, In: Journal of Proteome Research. 10, 6, p. 2703-14 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

    Rosenbaum, D. M., Cherezov, V., Hanson, M. A., Rasmussen, Søren Gøgsig Faarup, Thian, F. S., Kobilka, T. S., Choi, H., Yao, X., Weis, W. I., Stevens, R. C. & Kobilka, B. K., 23 Nov 2007, In: Science (New York, N.Y.). 318, 5854, p. 1266-73 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Structure and function of an irreversible agonist-β(2) adrenoceptor complex

    Rosenbaum, D. M., Zhang, C., Lyons, J. A., Holl, R., Aragao, D., Arlow, D. H., Rasmussen, Søren Gøgsig Faarup, Choi, H., Devree, B. T., Sunahara, R. K., Chae, P. S., Gellman, S. H., Dror, R. O., Shaw, D. E., Weis, W. I., Caffrey, M., Gmeiner, P. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 236-40 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The structure and function of G-protein-coupled receptors

    Rosenbaum, D. M., Rasmussen, Søren Gøgsig Faarup & Kobilka, B. K., 21 May 2009, In: Nature. 459, 7245, p. 356-63 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The beta2 Adrenergic Receptor as a Model for G Protein-Coupled Receptor Structure and Activation by Diffusible Hormones

    Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & Kobilka, B., Sep 2009, Handbook of Cell Signaling. Elsevier Editora

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  16. Published

    Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4

    Richter, W., Day, P., Agrawal, R., Bruss, M. D., Granier, S., Wang, Y. L., Rasmussen, Søren Gøgsig Faarup, Horner, K., Wang, P., Lei, T., Patterson, A. J., Kobilka, B. & Conti, M., 23 Jan 2008, In: E M B O Journal. 27, 2, p. 384-93 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

    Rasmussen, Søren Gøgsig Faarup, Choi, H., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I. & Kobilka, B. K., 13 Jan 2011, In: Nature. 469, 7329, p. 175-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

    Rasmussen, Søren Gøgsig Faarup, Choi, H., Rosenbaum, D. M., Kobilka, T. S., Thian, F. S., Edwards, P. C., Burghammer, M., Ratnala, V. R. P., Sanishvili, R., Fischetti, R. F., Schertler, G. F. X., Weis, W. I. & Kobilka, B. K., 15 Nov 2007, In: Nature. 450, 7168, p. 383-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Molecular mechanisms of GPCR activation

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2006, G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity. 2006: Wiley, Vol. 24. p. 27-42 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  20. Published

    Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI

    Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In: Molecular Pharmacology. 56, p. 175-184

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Crystal structure of the β2 adrenergic receptor-Gs protein complex

    Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, Jesper M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K., 29 Sep 2011, In: Nature. 477, 7366, p. 549-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

    Rasmussen, Søren Gøgsig Faarup, Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (7), p. 4717-4723

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Understanding G-protein coupled receptors and their role in the CNS

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  24. Published

    Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy

    Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Purification and fluorescent labeling of the human serotonin transporter

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In: Biochemistry. 44, 9, p. 3494-505 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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