Ole Kiehn

Ole Kiehn

Professor


  1. Published

    Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

    Allodi, Ilary, Montañana-Rosell, Roser, Selvan, Raghav, Löw, P. & Kiehn, Ole, 31 May 2021, In: Nature Communications. 12, 1, 17 p., 3251.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Modeling Motor Neuron Resilience in ALS Using Stem Cells

    Allodi, Ilary, Nijssen, J., Benitez, J. A., Schweingruber, C., Fuchs, A., Bonvicini, G., Cao, M., Kiehn, Ole & Hedlund, E., 2019, In: Stem Cell Reports. 12, 6, p. 1329-1341 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Reliability of neural encoding

    Alstrøm, P., Beierholm, U., Nielsen, C. D., Ryge, J. & Kiehn, Ole, 1 Dec 2002, In: Physica A: Statistical Mechanics and its Applications. 314, 1-4, p. 61-68 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Motor systems

    Anderson, M. E. & Kiehn, Ole, 1 Dec 2004, In: Current Opinion in Neurobiology. 14, 6, p. 661-664 4 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  5. Published

    Characterization of reliability of spike timing in spinal interneurons during oscillating inputs

    Beierholm, U., Nielsen, C. D., Ryge, J., Alstrøm, P. & Kiehn, Ole, 22 Oct 2001, In: Journal of Neurophysiology. 86, 4, p. 1858-1868 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Phenotypic characterization of speed-associated gait changes in mice reveals modular organization of locomotor networks

    Bellardita, Carmelo & Kiehn, Ole, 2015, In: Current Biology. 25, 11, p. 1426-1436 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Spatiotemporal correlation of spinal network dynamics underlying spasms in chronic spinalized mice

    Bellardita, Carmelo, Caggiano, V., Leiras, Roberto, Caldeira, V., Fuchs, A., Bouvier, J., Löw, P. & Kiehn, Ole, 13 Feb 2017, In: eLife. 6, 23 p., e23011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Sacral Spinal Cord Transection and Isolated Sacral Cord Preparation to Study Chronic Spinal Cord Injury in Adult Mice

    Bellardita, Carmelo, Marcantoni, M., Löw, P. & Kiehn, Ole, 2018, In: Bio-protocol. 8, 7, e2784.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Excitatory Spinal Lhx9-Derived Interneurons Modulate Locomotor Frequency in Mice

    Bertho, Maelle Claire Valentine, Caldeira, V., Hsu, Li-Ju, Löw, P., Borgius, L. & Kiehn, Ole, 2024, In: Journal of Neuroscience. 44, 18, 25 p., e1607232024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Synaptic targets of commissural interneurons in the lumbar spinal cord of neonatal rats

    Birinyi, A., Viszokay, K., Wéber, I., Kiehn, Ole & Antal, M., 7 Jul 2003, In: Journal of Comparative Neurology. 461, 4, p. 429-440 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A transgenic mouse line for molecular genetic analysis of excitatory glutamatergic neurons

    Borgius, L., Restrepo, C. E., Leao, R. N., Saleh, N. & Kiehn, Ole, 1 Nov 2010, In: Molecular and Cellular Neuroscience. 45, 3, p. 245-257 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Spinal glutamatergic neurons defined by EphA4 signaling are essential components of normal locomotor circuits

    Borgius, L., Nishimaru, H., Caldeira, V., Kunugise, Y., Löw, P., Reig, R., Itohara, S., Iwasato, T. & Kiehn, Ole, 1 Jan 2014, In: Journal of Neuroscience. 34, 11, p. 3841-3853 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Descending Command Neurons in the Brainstem that Halt Locomotion

    Bouvier, J., Caggiano, V., Leiras, Roberto, Caldeira, V., Bellardita, Carmelo, Balueva, K., Fuchs, A. & Kiehn, Ole, 19 Nov 2015, In: Cell. 163, 5, p. 1191-1203 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    EphA4 defines a class of excitatory locomotor-related interneurons

    Butt, S. J. B., Lundfald, L. & Kiehn, Ole, 27 Sep 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 39, p. 14098-14103 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Firing properties of identified interneuron populations in the mammalian hindlimb central pattern generator

    Butt, S. J. B., Harris-Warrick, R. M. & Kiehn, Ole, 15 Nov 2002, In: Journal of Neuroscience. 22, 22, p. 9961-9971 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Organization of left-right coordination in the mammalian locomotor network

    Butt, S. J. B., Lebret, J. M. & Kiehn, Ole, 1 Oct 2002, In: Brain Research. 40, 1-3, p. 107-117 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Functional identification of interneurons responsible for left-right coordination of hindlimbs in mammals

    Butt, S. J. B. & Kiehn, Ole, 19 Jun 2003, In: Neuron. 38, 6, p. 953-963 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Midbrain circuits that set locomotor speed and gait selection

    Caggiano, V., Leiras, Roberto, Goñi Erro, Haizea, Masini, Debora, Bellardita, Carmelo, Bouvier, J., Caldeira, V., Fisone, G. & Kiehn, Ole, 2018, In: Nature. 553, 7689, p. 455-460 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Spinal Hb9::Cre-derived excitatory interneurons contribute to rhythm generation in the mouse

    Caldeira, V., Dougherty, K. J., Borgius, L. & Kiehn, Ole, 27 Jan 2017, In: Scientific Reports. 7, 12 p., 41369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Plateau potentials in alpha‐motoneurones induced by intravenous injection of L‐dopa and clonidine in the spinal cat.

    Conway, B. A., Hultborn, Hans, Kiehn, Ole & Mintz, I., 1 Nov 1988, In: The Journal of Physiology. 405, 1, p. 369-384 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Proprioceptive input resets central locomotor rhythm in the spinal cat

    Conway, B. A., Hultborn, Hans & Kiehn, Ole, 1 Nov 1987, In: Experimental Brain Research. 68, 3, p. 643-656 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Brainstem Neurons that Command Left/Right Locomotor Asymmetries

    Cregg, Jared, Leiras, Roberto, Montalant, A., Wickersham, I. R. & Kiehn, Ole, 2019, 22 p.

    Research output: Working paperPreprintResearch

  23. Published

    Brainstem neurons that command mammalian locomotor asymmetries

    Cregg, Jared, Leiras, Roberto, Montalant, A., Wanken, P., Wickersham, I. R. & Kiehn, Ole, 2020, In: Nature Neuroscience. 23, p. 730-740 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Basal ganglia–spinal cord pathway that commands locomotor gait asymmetries in mice

    Cregg, Jared, Sidhu, Simrandeep Kaur, Leiras, Roberto & Kiehn, Ole, 2024, In: Nature Neuroscience. 27, p. 716–727 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Maintained changes in motoneuronal excitability by short‐lasting synaptic inputs in the decerebrate cat.

    Crone, C., Hultborn, Hans, Kiehn, Ole, Mazieres, L. & Wigström, H., 1 Nov 1988, In: The Journal of Physiology. 405, 1, p. 321-343 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genetic Ablation of V2a Ipsilateral Interneurons Disrupts Left-Right Locomotor Coordination in Mammalian Spinal Cord

    Crone, S. A., Quinlan, K. A., Zagoraiou, L., Droho, S., Restrepo, C. E., Lundfald, L., Endo, T., Setlak, J., Jessell, T. M., Kiehn, Ole & Sharma, K., 9 Oct 2008, In: Neuron. 60, 1, p. 70-83 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Locomotor Rhythm Generation Linked to the Output of Spinal Shox2 Excitatory Interneurons

    Dougherty, K. J., Zagoraiou, L., Satoh, D., Rozani, I., Doobar, S., Arber, S., Jessell, T. M. & Kiehn, Ole, 20 Nov 2013, In: Neuron. 80, 4, p. 920-933 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Functional organization of V2a-related locomotor circuits in the rodent spinal cord

    Dougherty, K. J. & Kiehn, Ole, 1 Jan 2010, Neurons and Networks in the Spinal Cord. Wiley-Blackwell, p. 85-93 9 p. (Annals of the New York Academy of Sciences, Vol. 1198).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  29. Published

    Firing and cellular properties of V2a interneurons in the rodent spinal cord

    Dougherty, K. J. & Kiehn, Ole, 6 Jan 2010, In: Journal of Neuroscience. 30, 1, p. 24-37 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Bistable firing properties of soleus motor units in unrestrained rats

    EKEN, T. & Kiehn, Ole, 1 Jan 1989, In: Acta Physiologica Scandinavica. 136, 3, p. 383-394 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function

    Egea, J., Nissen, U. V., Dufour, A., Sahin, M., Greer, P., Kullander, K., Mrsic-Flogel, T. D., Greenberg, M. E., Kiehn, Ole, Vanderhaeghen, P. & Klein, R., 18 Aug 2005, In: Neuron. 47, 4, p. 515-528 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Possible functions of transmitter-controlled plateau potentials in α motoneurones

    Eken, T., Hultborn, Hans & Kiehn, Ole, 1 Jan 1989, In: Progress in Brain Research. 80, C, p. 257-267 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Asymmetric operation of the locomotor central pattern generator in the neonatal mouse spinal cord

    Endo, T. & Kiehn, Ole, 1 Dec 2008, In: Journal of Neurophysiology. 100, 6, p. 3043-3054 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2014 års Nobelpris i fysiologi eller medicin - Nobelpristagarna har utforskat hjärnans inre GPS

    Forssberg, H. & Kiehn, Ole, 1 Jan 2014, In: Lakartidningen. 111, 41, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    V1 spinal neurons regulate the speed of vertebrate locomotor outputs

    Gosgnach, S., Lanuza, G. M., Butt, S. J. B., Saueressig, H., Zhang, Y., Velasquez, T., Riethmacher, D., Callaway, E. M., Kiehn, Ole & Goulding, M., 9 Mar 2006, In: Nature. 440, 7081, p. 215-219 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Pedunculopontine Chx10 + neurons control global motor arrest in mice.

    Goñi Erro, Haizea, Selvan, Raghav, Caggiano, V., Leiras, Roberto & Kiehn, Ole, 2023, In: Nature Neuroscience. 26, p. 1516–1528 43 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Networks in Motion

    Grillner, S., El Manira, A., Kiehn, Ole, Rossignol, S. & Stein, P., 1 Jan 2008, In: Brain Research. 57, 1, 1 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  38. Published

    The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance

    Holz, A., Kollmus, H., Ryge, J., Niederkofler, V., Dias, J., Ericson, J., Stoeckli, E. T., Kiehn, Ole & Arnold, H. H., 15 Dec 2010, In: Development. 137, 24, p. 4249-4260 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Serotonin‐induced bistability of turtle motoneurones caused by a nifedipine‐sensitive calcium plateau potential.

    Hounsgaard, Jørn Dybkjær & Kiehn, Ole, 1 Jul 1989, In: The Journal of Physiology. 414, 1, p. 265-282 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Ca++ dependent bistability induced by serotonin in spinal motoneurons

    Hounsgaard, Jørn Dybkjær & Kiehn, Ole, 1 Jan 1985, In: Experimental Brain Research. 57, 2, p. 422-425 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Evidence for voltage-sensitive sodium channels and N- and L-like calcium channels in distal dendrites of spinal motoneurones in an in vitro preparation from the turtle

    Hounsgaard, Jørn Dybkjær & Kiehn, Ole, 1 Jan 1990, In: Journal of Physiology. 424

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Transmitter-controlled properties of α-motoneurones causing long-lasting motor discharge to brief excitatory inputs

    Hounsgaard, Jørn Dybkjær, Hultborn, Hans & Kiehn, Ole, 1 Jan 1986, In: Progress in Brain Research. 64, C, p. 39-49 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Bistability of alpha‐motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5‐hydroxytryptophan.

    Hounsgaard, Jørn Dybkjær, Hultborn, Hans, Jespersen, B. & Kiehn, Ole, 1 Nov 1988, In: The Journal of Physiology. 405, 1, p. 345-367 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Response properties of motoneurones in a slice preparation of the turtle spinal cord.

    Hounsgaard, Jørn Dybkjær, Kiehn, Ole & Mintz, I., 1 Apr 1988, In: The Journal of Physiology. 398, 1, p. 575-589 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Intrinsic membrane properties causing a bistable behaviour of α-motoneurones

    Hounsgaard, Jørn Dybkjær, Hultborn, Hans, Jespersen, B. & Kiehn, Ole, 1 Jun 1984, In: Experimental Brain Research. 55, 2, p. 391-394 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Deconstructing the modular organization and real-time dynamics of mammalian spinal locomotor networks

    Hsu, Li-Ju, Bertho, Maelle Claire Valentine & Kiehn, Ole, 2023, In: Nature Communications. 14, 1, 18 p., 873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Neuromodulation of vertebrate motor neuron membrane properties

    Hultborn, Hans & Kiehn, Ole, 1 Jan 1992, In: Current Opinion in Neurobiology. 2, 6, p. 770-775 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

    Hägglund, M., Borgius, L., Dougherty, K. J. & Kiehn, Ole, 18 Feb 2010, In: Nature Neuroscience. 13, 2, p. 246-252 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion

    Hägglund, M., Dougherty, K. J., Borgius, L., Itohara, S., Iwasato, T. & Kiehn, Ole, 9 Jul 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 28, p. 11589-11594 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

    Häring, M., Zeisel, A., Hochgerner, H., Rinwa, P., Jakobsson, J. E. T., Lönnerberg, P., La Manno, G., Sharma, N., Borgius, L., Kiehn, Ole, Lagerström, M. C., Linnarsson, S. & Ernfors, P., 2018, In: Nature Neuroscience. 21, 6, p. 869-880 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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