Jakob Balslev Sørensen
Professor
Neuronal Signalling
Blegdamsvej 3
2200 København N.
- 2024
- Published
Protocol for quantifying pyramidal neuron hyperexcitability in a mouse model of neurodevelopmental encephalopathy
Brito dos Santos, Altair, Larsen, Silas Dalum, Gomez Martinez, Carlos Daniel, Sørensen, Jakob Balslev & Perrier, Jean-Francois Marie, 2024, In: STAR Protocols. 5, 2, 12 p., 102954.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions
Kádková, Anna, Murach, J., Pedersen, Maiken Østergaard, Malsam, A., Malsam, J., Lolicato, F., Nickel, W., Söllner, T. H. & Sørensen, Jakob Balslev, 2024, In: eLife. 12, 44 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
An Improved Method for Growing Primary Neurons on Electron Microscopy Grids Co-Cultured with Astrocytes
Kumar, I., Paudyal, A., Kádková, Anna, Stewart, M., Sørensen, Jakob Balslev & Radecke, J., 2023, In: International Journal of Molecular Sciences. 24, 20, 15 p., 15191.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcircuit failure in STXBP1 encephalopathy leads to hyperexcitability
Brito dos Santos, Altair, Larsen, Silas Dalum, Guo, L., Barbagallo, Paola, Montalant, A., Verhage, M., Sørensen, Jakob Balslev & Perrier, Jean-Francois Marie, 2023, In: Cell Reports Medicine. 4, 12, 19 p., 101308.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morphofunctional changes at the active zone during synaptic vesicle exocytosis
Radecke, J., Seeger, R., Kádková, Anna, Laugks, U., Khosrozadeh, A., Goldie, K. N., Lučić, V., Sørensen, Jakob Balslev & Zuber, B., 2023, In: EMBO Reports. 24, 5, 16 p., e55719.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Allosteric stabilization of calcium and phosphoinositide dual binding engages several synaptotagmins in fast exocytosis
Kobbersmed, J. R. L., Berns, M. M. M., Ditlevsen, Susanne, Sørensen, Jakob Balslev & Walter, Alexander Matthias, 2022, In: eLife. 11, 34 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phorbolester-activated Munc13-1 and ubMunc13-2 exert opposing effects on dense-core vesicle secretion
Houy, S., Silvestre Martins, Joana Andreia, Lipstein, N. & Sørensen, Jakob Balslev, 2022, In: eLife. 11, 26 p., e79433.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Allosteric stabilization of calcium and lipid binding engages three synaptotagmins in fast exocytosis
Kobbersmed, J. R. L., Berns, M. M. M., Ditlevsen, Susanne, Sørensen, Jakob Balslev & Walter, Alexander Matthias, 23 Oct 2021, bioRxiv, p. 1-56.Research output: Working paper › Preprint › Research
- Published
Introducing the special issue on “Proteins and Circuits in Memory”
Kjærgaard, M., Petersen, Nicolas Caesar, Sørensen, Jakob Balslev & Takeuchi, T., 2021, In: European Journal of Neuroscience. 54, 8, p. 6691-6695 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Measurements of Exocytosis by Capacitance Recordings and Calcium Uncaging in Mouse Adrenal Chromaffin Cells
Houy, S., Martins, J. S., Mohrmann, R. & Sørensen, Jakob Balslev, 2021, Methods in Molecular Biology. Niedergang, F., Vitale, N. & Gasman, S. (eds.). 1 ed. New Yorj: Humana Press, p. 233-251 19 p. (Methods in Molecular Biology, Vol. 2233).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming
Tawfik, B., Martins, J. S., Houy, Sebastien Nicolas Julien, Imig, Cordelia, Pinheiro, P. S., Wojcik, S. M., Brose, N., Cooper, B. H. & Sørensen, Jakob Balslev, 2021, In: eLife. 10, 40 p., e64527.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
Gowrisankaran, S., Houy, S., del Castillo, J. G. P., Steubler, V., Gelker, M., Kroll, J., Pinheiro, P. S., Schwitters, D., Halbsgut, N., Pechstein, A., van Weering, J. R. T., Maritzen, T., Haucke, V., Raimundo, N., Sørensen, Jakob Balslev & Milosevic, I., 2020, In: Nature Communications. 11, 1, 1266.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle: Ca2+ channel distances
Kobbersmed, J. R. L., Grasskamp, A. T., Jusyte, M., Boehme, M. A., Ditlevsen, Susanne, Sørensen, Jakob Balslev & Walter, Alexander Matthias, 2020, In: eLife. 9, 48 p., e51032.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNAP-25 phosphorylation at Ser187 is not involved in Ca2+ or phorbolester-dependent potentiation of synaptic release
Ruiter, M., Houy, S., Engholm-Keller, Kasper, Graham, M. E. & Sørensen, Jakob Balslev, 2020, In: Molecular and Cellular Neuroscience. 102, 103452.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNAREopathies: Diversity in Mechanisms and Symptoms
Verhage, M. & Sørensen, Jakob Balslev, 2020, In: Neuron. 107, 1, p. 22-37 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission
Wierda, K. D. B., Toft-Bertelsen, Trine Lisberg, Gøtzsche, C. R., Pedersen, E., Korshunova, Irina, Nielsen, J., Bang, M. L., Kønig, A. B., Owczarek, S., Gjørlund, M. D., Schupp, M., Bock, E. & Sørensen, Jakob Balslev, 2020, In: Scientific Reports. 10, 1, 15 p., 18041.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A possible postsynaptic role for SNAP-25 in hippocampal synapses
Hussain, S., Ringsevjen, H., Schupps, M., Hvalby, Ø., Sørensen, Jakob Balslev, Jensen, V. & Davanger, S., 2019, In: Brain Structure and Function. 224, 2, p. 521-532Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Electrostatic Energy Barrier for SNARE-Dependent Spontaneous and Evoked Synaptic Transmission
Ruiter, M., Kádková, Anna, Scheutzow, A., Malsam, J., Söllner, T. H. & Sørensen, Jakob Balslev, 2019, In: Cell Reports. 26, 9, p. 2340-2352, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MUNC18-1 regulates the submembrane F-actin network, independently of syntaxin1 targeting, via hydrophobicity in beta-sheet 10
Pons-Vizcarra, M., Kurps, J., Tawfik, B., Sørensen, Jakob Balslev, van Weering, J. R. T. & Verhage, M., 2019, In: Journal of Cell Science. 132, 23, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SNAP-25 protein family
Kádková, Anna, Radecke, J. & Sørensen, Jakob Balslev, 2019, In: Neuroscience. 420, p. 50-71 22 p.Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Doc2B acts as a calcium sensor for vesicle priming requiring synaptotagmin-1, Munc13-2 and SNAREs
Houy, S., Groffen, A. J., Ziomkiewicz, I., Verhage, M., Pinheiro, P. S. & Sørensen, Jakob Balslev, 23 Dec 2017, In: eLife. 6, 29 p., e27000.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines
Hussain, S., Egbenya, D. L., Lai, Y., Dosa, Z. J., Sørensen, Jakob Balslev, Anderson, A. E. & Davanger, S., Nov 2017, In: Hippocampus. 27, 11, p. 1168-1177 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comment on "Penetration of Action Potentials During Collision in the Median and Lateral Giant Axons of Invertebrates"
Berg, Rune W., Stauning, M. T., Sørensen, Jakob Balslev & Jahnsen, Henrik, 2017, In: Physical Review X. 7, 2, 3 p., 028001.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
Walter, Alexander Matthias, Müller, R., Tawfik, B., Wierda, K. D., Pinheiro, P. S., Nadler, A., McCarthy, A. W., Ziomkiewicz, I., Kruse, M., Reither, G., Rettig, J., Lehmann, M., Haucke, V., Hille, B., Schultz, C. & Sørensen, Jakob Balslev, 2017, In: eLife. 6, 41 p., e30203.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ride the wave: Retrograde trafficking becomes Ca(2+) dependent with BAIAP3
Sørensen, Jakob Balslev, 2017, In: Journal of Cell Biology. 216, 7, p. 1887-1889 3 p.Research output: Contribution to journal › Comment/debate › Research
- 2016
- Published
C2-domain containing calcium sensors in neuroendocrine secretion
Pinheiro, P. S., Houy, S. & Sørensen, Jakob Balslev, Dec 2016, In: Journal of Neurochemistry. 139, 6, p. 943-958Research output: Contribution to journal › Review › Research › peer-review
- Published
Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission
Schupp, M., Malsam, J., Ruiter, M., Scheutzow, A., Wierda, K. D. B., Söllner, T. H. & Sørensen, Jakob Balslev, 23 Nov 2016, In: Journal of Neuroscience. 36, 47, p. 11865-11880 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters
Toft-Bertelsen, Trine Lisberg, Ziomkiewicz, I., Houy, S., da Silva Pinheiro, P. C. & Sørensen, Jakob Balslev, 1 Nov 2016, In: Molecular Biology of the Cell. 27, 21, p. 3329-3341 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extension of Helix 12 in Munc18-1 Induces Vesicle Priming
Munch, A. S., Kedar, G. H., van Weering, J. R. T., Vazquez-Sanchez, S., He, E., André, T., Braun, T., Söllner, T. H., Verhage, M. & Sørensen, Jakob Balslev, 29 Jun 2016, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 36, 26, p. 6881-6891 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of synaptotagmin-1 controls a post-priming step in PKC-dependent presynaptic plasticity
de Jong, A. P. H., Meijer, M., Saarloos, I., Cornelisse, L. N., Toonen, R. F. G., Sørensen, Jakob Balslev & Verhage, M., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 13, 8, p. 5095–5100 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis
Man, K. M., Imig, Cordelia, Walter, A. M., da Silva Pinheiro, P. C., Stevens, D. R., Rettig, J., Sørensen, Jakob Balslev, Cooper, B. H., Brose, N. & Wojcik, S. M., 17 Nov 2015, In: eLife. 4, p. 1-28 28 p., e10635.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform
Axelsen, T. M., Navntoft, C. A. E., Christiansen, S. H., Dreyer, J. K., Sørensen, Jakob Balslev, Gether, Ulrik & Woldbye, David Paul Drucker, 17 Aug 2015, In: Ugeskrift for Laeger. 177, 34, p. 2-5 4 p., V06150501.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the Interaction Between Synaptotagmin-1 and SNARES using Mutations in SNAP-25
Schupp, M. & Sørensen, Jakob Balslev, 27 Jan 2015, In: Biophysical Journal. 108, 2, Supplement 1 , p. 102A-102A 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A Post-Docking Role of Synaptotagmin 1-C2B Domain Bottom Residues R398/399 in Mouse Chromaffin Cells
Kedar, G. H., Munch, A. S., van Weering, J. R. T., Malsam, J., Scheutzow, A., de Wit, H., Houy, S., Tawfik, B., Söllner, T. H., Sørensen, Jakob Balslev & Verhage, M., 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 42, p. 14172-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate
Schotten, S., Meijer, M., Walter, Alexander Matthias, Huson, V., Mamer, L., Kalogreades, L., Ter Veer, M., Ruiter, M., Brose, N., Rosenmund, C., Sørensen, Jakob Balslev, Verhage, M. & Cornelisse, L. N., 2015, In: eLife. 4, p. 1-25 25 p., e05531.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fusion Machinery: SNARE Protein Complex
Sørensen, Jakob Balslev & Milosevic, I., 2015, Presynaptic Terminals. Japan, p. 87-127 41 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Spatial distribution and temporal evolution of DRONPA-fused SNAP25 clusters in adrenal chromaffin cells
Antoku, Yasuko, Dedecker, P., da Silva Pinheiro, P. C., Vosch, Tom & Sørensen, Jakob Balslev, 2015, In: Photochemical & Photobiological Sciences. 14, 5, p. 1005-1012 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The BAR Domain Protein PICK1 Controls Vesicle Number and Size in Adrenal Chromaffin Cells
da Silva Pinheiro, P. C., Jansen, A. M., de Wit, H., Tawfik, B., Madsen, Kenneth Lindegaard, Verhage, M., Gether, Ulrik & Sørensen, Jakob Balslev, 6 Aug 2014, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 32, p. 10688-700 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SNARE protein vti1a functions in dense-core vesicle biogenesis
Walter, Alexander Matthias, Kurps, J., de Wit, H., Schöning, S., Toft-Bertelsen, Trine Lisberg, Lauks, J., Ziomkiewicz, I., Weiss, A. N., Schulz, Alexander, Fischer von Mollard, G., Verhage, M. & Sørensen, Jakob Balslev, 5 Jun 2014, In: E M B O Journal. 33, p. 1681-1697 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Innervation by a GABAergic neuron depresses spontaneous release in glutamatergic neurons and unveils the clamping phenotype of synaptotagmin-1
Wierda, K. D. B. & Sørensen, Jakob Balslev, 5 Feb 2014, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 6, p. 2100-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23
Weber, J. P., Toft-Bertelsen, Trine Lisberg, Mohrmann, R., Delgado-Martinez, I. & Sørensen, Jakob Balslev, 2014, In: PloS one. 9, 11, p. 1-22 22 p., e114033.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
A sequential vesicle pool model with a single release sensor and a ca(2+)-dependent priming catalyst effectively explains ca(2+)-dependent properties of neurosecretion
Walter, Alexander Matthias, da Silva Pinheiro, P. C., Verhage, M. & Sørensen, Jakob Balslev, Dec 2013, In: P L o S Computational Biology (Online). 9, 12, p. 1-15 15 p., e1003362.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Doc2b synchronizes secretion from chromaffin cells by stimulating fast and inhibiting sustained release
da Silva Pinheiro, P. C., de Wit, H., Walter, Alexander Matthias, Groffen, A. J., Verhage, M. & Sørensen, Jakob Balslev, 16 Oct 2013, In: Journal of Neuroscience. 33, 42, p. 16459-70 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering
Mohrmann, R., de Wit, H., Connell, E., da Silva Pinheiro, P. C., Leese, C., Bruns, D., Davletov, B., Verhage, M. & Sørensen, Jakob Balslev, 4 Sep 2013, In: Journal of Neuroscience. 33, 36, p. 14417-30 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
SNARE Requirements En Route to Exocytosis: from Many to Few
Mohrmann, R. & Sørensen, Jakob Balslev, 2012, In: Journal of Molecular Neuroscience. p. 387-394 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2011
- Published
Multiple Ca2+ sensors in secretion: teammates, competitors or autocrats?
Walter, Alexander Matthias, Groffen, A. J., Sørensen, Jakob Balslev & Verhage, M., 2011, In: Trends in Neurosciences. 34, 9, p. 487-97 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 2010
- Published
A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex
Wiederhold, K., Kloepper, T. H., Walter, A. M., Stein, A., Kienle, N., Sørensen, Jakob Balslev & Fasshauer, D., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21549-59 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes
Mohrmann, R., de Wit, H., Verhage, M., Neher, E. & Sørensen, Jakob Balslev, 2010, In: Science.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposing functions of two sub-domains of the SNARE-complex in neurotransmission
Weber, J. P., Reim, K. & Sørensen, Jakob Balslev, 2010, In: EMBO Journal. 29, 15, p. 2477-90 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells
Schonn, J., van Weering, J. R. T., Mohrmann, R., Schlüter, O. M., Südhof, T. C., de Wit, H., Verhage, M. & Sørensen, Jakob Balslev, 2010, In: Traffic - International Journal of Intracellular Transport.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of the synaptobrevin C terminus in fusion pore formation
Ngatchou, A. N., Kisler, K., Fang, Q., Walter, A. M., Zhao, Y., Bruns, D., Sørensen, Jakob Balslev & Lindau, M., 2010, In: Proceedings of the National Academy of Science of the United States of America.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis
Walter, A. M., Wiederhold, K., Bruns, D., Fasshauer, D. & Sørensen, Jakob Balslev, 2010, In: Journal of Cell Biology. 188, 3, p. 401-13 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Conflicting views on the membrane fusion machinery and the fusion pore
Sørensen, Jakob Balslev, 2009, In: Annual Review of Cell and Developmental Biology. 25, p. 513-37 24 p.Research output: Contribution to journal › Review › Research
- Published
Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes
de Wit, H., Walter, Alexander Matthias, Milosevic, I., Gulyás-Kovács, A., Riedel, D., Sørensen, Jakob Balslev & Verhage, M., 2009, In: Cell. 138, 5, p. 935-946 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vesicle Pools
Sørensen, Jakob Balslev, 2009, Encyclopedia of Neuroscience. Elsevier, p. 99-105 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2008
- Published
Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming
Cai, H., Reim, K., Varoqueaux, F., Tapechum, S., Hill, K., Sørensen, Jakob Balslev, Brose, N. & Chow, R. H., Dec 2008, In: PNAS Early Edition. 105, 49, p. 19538-43 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis
Maximov, A., Lao, Y., Li, H., Chen, X., Rizo, J., Sørensen, Jakob Balslev & Südhof, T. C., 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 10, p. 3986-91 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synaptotagmin-1 and -7 are functionally overlapping Ca2+ sensors for exocytosis in adrenal chromaffin cells
Schonn, J., Maximov, A., Lao, Y., Südhof, T. C. & Sørensen, Jakob Balslev, 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 10, p. 3998-4003 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
The SNAP-25 linker as an adaptation toward fast exocytosis
Nagy, G., Milosevic, I., Mohrmann, R., Wiederhold, K., Walter, A. M. & Sørensen, Jakob Balslev, 2008, In: Molecular Biology of the Cell. 19, 9, p. 3769-81 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics
Fang, Q., Berberian, K., Gong, L., Hafez, I., Sørensen, Jakob Balslev & Lindau, M., 2008, In: Proceedings of the National Academy of Science of the United States of America. 105, 40, p. 15388-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Vesicle docking in regulated exocytosis
Verhage, M. & Sørensen, Jakob Balslev, 2008, In: Traffic - International Journal of Intracellular Transport. 9, 9, p. 1414-24 10 p.Research output: Contribution to journal › Review › Research
- 2007
CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins
Jockusch, W. J., Speidel, D., Sigler, A., Sørensen, Jakob Balslev, Varoqueaux, F., Rhee, J. & Brose, N., 2007, In: Cell. 131, 4, p. 796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Differential abilities of SNAP-25 homologs to support neuronal function
Delgado-Martínez, I., Nehring, R. B. & Sørensen, Jakob Balslev, 2007, In: Journal of Neuroscience. 27, 35, p. 9380-91 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming
Gulyás-Kovács, A., de Wit, H., Milosevic, I., Kochubey, O., Toonen, R., Klingauf, J., Verhage, M. & Sørensen, Jakob Balslev, 2007, In: Journal of Neuroscience. 27, 32, p. 8676-86 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells
Nili, U., de Wit, H., Gulyas-Kovacs, A., Toonen, R. F., Sørensen, Jakob Balslev, Verhage, M. & Ashery, U., 1 Dec 2006, In: Neuroscience. 143, 2, p. 487-500 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation
Nagy, G., Kim, J. H., Pang, Z. P., Matti, U., Rettig, J., Südhof, T. C. & Sørensen, Jakob Balslev, 2006, In: Journal of Neuroscience. 26, 2, p. 632-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Dissecting docking and tethering of secretory vesicles at the target membrane
Toonen, R. F., Kochubey, O., de Wit, H., Gulyas-Kovacs, A., Konijnenburg, B., Sørensen, Jakob Balslev, Klingauf, J. & Verhage, M., 2006, In: EMBO Journal. 25, 16, p. 3725-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes
Zilly, F. E., Sørensen, Jakob Balslev, Jahn, R. & Lang, T., 2006, In: PLoS - Biology. 4, 10, p. e330Research output: Contribution to journal › Journal article › Research › peer-review
Sequential N- to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles
Sørensen, Jakob Balslev, Wiederhold, K., Müller, E. M., Milosevic, I., Nagy, G., de Groot, B. L., Grubmüller, H. & Fasshauer, D., 2006, In: EMBO Journal. 25, 5, p. 955-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Alternative splicing of SNAP-25 regulates secretion through nonconservative substitutions in the SNARE domain
Nagy, G., Milosevic, I., Fasshauer, D., Müller, E. M., de Groot, B. L., Lang, T., Wilson, M. C. & Sørensen, Jakob Balslev, 2005, In: Molecular Biology of the Cell. 16, 12, p. 5675-85 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells
Milosevic, I., Sørensen, Jakob Balslev, Lang, T., Krauss, M., Nagy, G., Haucke, V., Jahn, R. & Neher, E., 2005, In: Journal of Neuroscience. 25, 10, p. 2557-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
SNARE complexes prepare for membrane fusion
Sørensen, Jakob Balslev, 2005, In: TINS - Trends in Neurosciences. 28, 9, p. 453-5 2 p.Research output: Contribution to journal › Review › Research
- 2004
Formation, stabilisation and fusion of the readily releasable pool of secretory vesicles
Sørensen, Jakob Balslev, 2004, In: Pflügers Archiv: European Journal of Physiology. 448, 4, p. 347-62 15 p.Research output: Contribution to journal › Review › Research
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25
Nagy, G., Reim, K., Matti, U., Brose, N., Binz, T., Rettig, J., Neher, E. & Sørensen, Jakob Balslev, 2004, In: Neuron. 41, 3, p. 417-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
Differential control of the releasable vesicle pools by SNAP-25 splice variants and SNAP-23
Sørensen, Jakob Balslev, Nagy, G., Varoqueaux, F., Nehring, R. B., Brose, N., Wilson, M. C. & Neher, E., 2003, In: Cell. 114, 1, p. 75-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+
Sørensen, Jakob Balslev, Fernández-Chacón, R., Südhof, T. C. & Neher, E., 2003, In: Journal of General Physiology. 122, 3, p. 265-76 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
The SNARE protein SNAP-25 is linked to fast calcium triggering of exocytosis
Sørensen, Jakob Balslev, Matti, U., Wei, S. H., Nehring, R. B., Voets, T., Ashery, U., Binz, T., Neher, E. & Rettig, J., 5 Feb 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1627-1632 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of the sodium recirculation theory of solute-coupled water transport in small intestine
Larsen, Erik Hviid, Sørensen, Jakob Balslev & Sørensen, J. N., 2002, In: Journal of Physiology. 542, Pt 1, p. 33-50 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein kinase C-dependent phosphorylation of synaptosome-associated protein of 25 kDa at Ser187 potentiates vesicle recruitment
Nagy, G., Matti, U., Nehring, R. B., Binz, T., Rettig, J., Neher, E. & Sørensen, Jakob Balslev, 2002, In: Journal of Neuroscience. 22, 21, p. 9278-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Patch clamp on the luminal membrane of exocrine gland acini from frog skin (Rana esculenta) reveals the presence of cystic fibrosis transmembrane conductance regulator-like Cl- channels activated by cyclic AMP
Sørensen, Jakob Balslev & Larsen, Erik Hviid, Jul 1998, In: Journal of General Physiology. 112, 1, p. 19-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Whole-cell patch-clamp studies of exocrine glands from frog skin (Rana esculenta)
Sørensen, Jakob Balslev & Larsen, Erik Hviid, 1997, In: FASEB Journal. 11, 3, p. A306Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
A method of modelling time dependent data: swimming in guppies (Poecilia Reticulata) under threat of a predator
Bildsøe, M. & Sørensen, Jakob Balslev, Feb 1994, In: Behavioural Processes. 31, 1, p. 75-96 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9847273
Most downloads
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363
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Spatial distribution and temporal evolution of DRONPA-fused SNAP25 clusters in adrenal chromaffin cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
254
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Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
249
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Ride the wave: Retrograde trafficking becomes Ca(2+) dependent with BAIAP3
Research output: Contribution to journal › Comment/debate › Research
Published