Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy. / Lorentzen, Jakob; Born, Alfred P.; Svane, Christian; Forman, Christian; Laursen, Bjarne; Langkilde, Annika R.; Uldall, Peter; Hoei-Hansen, Christina E.

In: Acta Paediatrica, International Journal of Paediatrics, Vol. 111, No. 2, 2022, p. 323-335.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lorentzen, J, Born, AP, Svane, C, Forman, C, Laursen, B, Langkilde, AR, Uldall, P & Hoei-Hansen, CE 2022, 'Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy', Acta Paediatrica, International Journal of Paediatrics, vol. 111, no. 2, pp. 323-335. https://doi.org/10.1111/apa.16152

APA

Lorentzen, J., Born, A. P., Svane, C., Forman, C., Laursen, B., Langkilde, A. R., Uldall, P., & Hoei-Hansen, C. E. (2022). Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy. Acta Paediatrica, International Journal of Paediatrics, 111(2), 323-335. https://doi.org/10.1111/apa.16152

Vancouver

Lorentzen J, Born AP, Svane C, Forman C, Laursen B, Langkilde AR et al. Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy. Acta Paediatrica, International Journal of Paediatrics. 2022;111(2):323-335. https://doi.org/10.1111/apa.16152

Author

Lorentzen, Jakob ; Born, Alfred P. ; Svane, Christian ; Forman, Christian ; Laursen, Bjarne ; Langkilde, Annika R. ; Uldall, Peter ; Hoei-Hansen, Christina E. / Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy. In: Acta Paediatrica, International Journal of Paediatrics. 2022 ; Vol. 111, No. 2. pp. 323-335.

Bibtex

@article{a01c4b78f3bd44b6b291535cdcd22ef5,
title = "Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy",
abstract = "Aim: Children with dyskinetic cerebral palsy (CP) are often severely affected and effective treatment is difficult, due to different underlying disease mechanisms. Comprehensive systematic movement disorder evaluations were carried out on patients with this disorder. Methods: Patients born from 1995 to 2007 were identified from the Danish Cerebral Palsy Register and referrals to the neuropaediatric centre, Rigshospitalet, Copenhagen. They were classified by gross motor function, manual functional ability, communication ability, dystonia and spasticity. Electromyography was carried out on the upper and lower limbs. Magnetic resonance imaging scans were revised, and aetiological searches for underlying genetic disorders were performed. Results: We investigated 25 patients with dyskinetic CP at a mean age of 11.7 years. Dystonia, spasticity and rigidity were found in the upper limbs of 21, four and six children, respectively, and in the lower limbs of 18, 18 and three children. The mean total Burke-Fahn-Marsden score for dystonia was 45.02, and the mean Disability Impairment Scale level was 38% for dystonia and 13% for choreoathetosis. Sustained electromyography activity was observed in 20/25 children. Stretching increased electromyography activity more in children with spasticity. There were 10 re-classifications. Conclusion: The children had heterogenic characteristics, and 40% were reclassified after systematic movement disorder evaluation.",
keywords = "cerebral palsy, dystonia, electromyography, genetics, imaging",
author = "Jakob Lorentzen and Born, {Alfred P.} and Christian Svane and Christian Forman and Bjarne Laursen and Langkilde, {Annika R.} and Peter Uldall and Hoei-Hansen, {Christina E.}",
note = "Publisher Copyright: {\textcopyright} 2021 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd",
year = "2022",
doi = "10.1111/apa.16152",
language = "English",
volume = "111",
pages = "323--335",
journal = "Acta Paediatrica",
issn = "0803-5253",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Using both electromyography and movement disorder assessment improved the classification of children with dyskinetic cerebral palsy

AU - Lorentzen, Jakob

AU - Born, Alfred P.

AU - Svane, Christian

AU - Forman, Christian

AU - Laursen, Bjarne

AU - Langkilde, Annika R.

AU - Uldall, Peter

AU - Hoei-Hansen, Christina E.

N1 - Publisher Copyright: © 2021 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd

PY - 2022

Y1 - 2022

N2 - Aim: Children with dyskinetic cerebral palsy (CP) are often severely affected and effective treatment is difficult, due to different underlying disease mechanisms. Comprehensive systematic movement disorder evaluations were carried out on patients with this disorder. Methods: Patients born from 1995 to 2007 were identified from the Danish Cerebral Palsy Register and referrals to the neuropaediatric centre, Rigshospitalet, Copenhagen. They were classified by gross motor function, manual functional ability, communication ability, dystonia and spasticity. Electromyography was carried out on the upper and lower limbs. Magnetic resonance imaging scans were revised, and aetiological searches for underlying genetic disorders were performed. Results: We investigated 25 patients with dyskinetic CP at a mean age of 11.7 years. Dystonia, spasticity and rigidity were found in the upper limbs of 21, four and six children, respectively, and in the lower limbs of 18, 18 and three children. The mean total Burke-Fahn-Marsden score for dystonia was 45.02, and the mean Disability Impairment Scale level was 38% for dystonia and 13% for choreoathetosis. Sustained electromyography activity was observed in 20/25 children. Stretching increased electromyography activity more in children with spasticity. There were 10 re-classifications. Conclusion: The children had heterogenic characteristics, and 40% were reclassified after systematic movement disorder evaluation.

AB - Aim: Children with dyskinetic cerebral palsy (CP) are often severely affected and effective treatment is difficult, due to different underlying disease mechanisms. Comprehensive systematic movement disorder evaluations were carried out on patients with this disorder. Methods: Patients born from 1995 to 2007 were identified from the Danish Cerebral Palsy Register and referrals to the neuropaediatric centre, Rigshospitalet, Copenhagen. They were classified by gross motor function, manual functional ability, communication ability, dystonia and spasticity. Electromyography was carried out on the upper and lower limbs. Magnetic resonance imaging scans were revised, and aetiological searches for underlying genetic disorders were performed. Results: We investigated 25 patients with dyskinetic CP at a mean age of 11.7 years. Dystonia, spasticity and rigidity were found in the upper limbs of 21, four and six children, respectively, and in the lower limbs of 18, 18 and three children. The mean total Burke-Fahn-Marsden score for dystonia was 45.02, and the mean Disability Impairment Scale level was 38% for dystonia and 13% for choreoathetosis. Sustained electromyography activity was observed in 20/25 children. Stretching increased electromyography activity more in children with spasticity. There were 10 re-classifications. Conclusion: The children had heterogenic characteristics, and 40% were reclassified after systematic movement disorder evaluation.

KW - cerebral palsy

KW - dystonia

KW - electromyography

KW - genetics

KW - imaging

U2 - 10.1111/apa.16152

DO - 10.1111/apa.16152

M3 - Journal article

C2 - 34655503

AN - SCOPUS:85118846554

VL - 111

SP - 323

EP - 335

JO - Acta Paediatrica

JF - Acta Paediatrica

SN - 0803-5253

IS - 2

ER -

ID: 285183125