Serotonin 5-HT2 receptor availability in chronic cocaine abusers.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Serotonin 5-HT2 receptor availability in chronic cocaine abusers. / Wang, G J; Volkow, N D; Logan, J; Fowler, J S; Schlyer, D; MacGregor, R R; Hitzemann, R J; Gjedde, A; Wolf, A P.

In: Life Sciences, Vol. 56, No. 16, 1995, p. PL299-303.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Wang, GJ, Volkow, ND, Logan, J, Fowler, JS, Schlyer, D, MacGregor, RR, Hitzemann, RJ, Gjedde, A & Wolf, AP 1995, 'Serotonin 5-HT2 receptor availability in chronic cocaine abusers.', Life Sciences, vol. 56, no. 16, pp. PL299-303.

APA

Wang, G. J., Volkow, N. D., Logan, J., Fowler, J. S., Schlyer, D., MacGregor, R. R., Hitzemann, R. J., Gjedde, A., & Wolf, A. P. (1995). Serotonin 5-HT2 receptor availability in chronic cocaine abusers. Life Sciences, 56(16), PL299-303.

Vancouver

Wang GJ, Volkow ND, Logan J, Fowler JS, Schlyer D, MacGregor RR et al. Serotonin 5-HT2 receptor availability in chronic cocaine abusers. Life Sciences. 1995;56(16):PL299-303.

Author

Wang, G J ; Volkow, N D ; Logan, J ; Fowler, J S ; Schlyer, D ; MacGregor, R R ; Hitzemann, R J ; Gjedde, A ; Wolf, A P. / Serotonin 5-HT2 receptor availability in chronic cocaine abusers. In: Life Sciences. 1995 ; Vol. 56, No. 16. pp. PL299-303.

Bibtex

@article{440d48e0b31511debc73000ea68e967b,
title = "Serotonin 5-HT2 receptor availability in chronic cocaine abusers.",
abstract = "Serotonin 5-HT2 receptor availability was evaluated in chronic cocaine abusers (n = 19) using positron emission tomography and F-18 N-methylspiperone and was compared to control subjects (n =19). 5-HT2 Receptor availability was measured in frontal, occipital, cingulate and orbitofrontal cortices using the ratio of the distribution volume in the region of interest to that in the cerebellum which is a function of Bmax/Kd. 5-HT2 Receptor availability was significantly higher in cingulate and orbitofrontal cortices than in other frontal regions or occipital cortex. The values were not different in normal subjects and cocaine abusers. These results did not show any changes in 5-HT2 receptor availability in cocaine abusers as compared to the control subjects.",
author = "Wang, {G J} and Volkow, {N D} and J Logan and Fowler, {J S} and D Schlyer and MacGregor, {R R} and Hitzemann, {R J} and A Gjedde and Wolf, {A P}",
year = "1995",
language = "English",
volume = "56",
pages = "PL299--303",
journal = "Life Sciences",
issn = "0024-3205",
publisher = "Elsevier",
number = "16",

}

RIS

TY - JOUR

T1 - Serotonin 5-HT2 receptor availability in chronic cocaine abusers.

AU - Wang, G J

AU - Volkow, N D

AU - Logan, J

AU - Fowler, J S

AU - Schlyer, D

AU - MacGregor, R R

AU - Hitzemann, R J

AU - Gjedde, A

AU - Wolf, A P

PY - 1995

Y1 - 1995

N2 - Serotonin 5-HT2 receptor availability was evaluated in chronic cocaine abusers (n = 19) using positron emission tomography and F-18 N-methylspiperone and was compared to control subjects (n =19). 5-HT2 Receptor availability was measured in frontal, occipital, cingulate and orbitofrontal cortices using the ratio of the distribution volume in the region of interest to that in the cerebellum which is a function of Bmax/Kd. 5-HT2 Receptor availability was significantly higher in cingulate and orbitofrontal cortices than in other frontal regions or occipital cortex. The values were not different in normal subjects and cocaine abusers. These results did not show any changes in 5-HT2 receptor availability in cocaine abusers as compared to the control subjects.

AB - Serotonin 5-HT2 receptor availability was evaluated in chronic cocaine abusers (n = 19) using positron emission tomography and F-18 N-methylspiperone and was compared to control subjects (n =19). 5-HT2 Receptor availability was measured in frontal, occipital, cingulate and orbitofrontal cortices using the ratio of the distribution volume in the region of interest to that in the cerebellum which is a function of Bmax/Kd. 5-HT2 Receptor availability was significantly higher in cingulate and orbitofrontal cortices than in other frontal regions or occipital cortex. The values were not different in normal subjects and cocaine abusers. These results did not show any changes in 5-HT2 receptor availability in cocaine abusers as compared to the control subjects.

M3 - Journal article

C2 - 8614247

VL - 56

SP - PL299-303

JO - Life Sciences

JF - Life Sciences

SN - 0024-3205

IS - 16

ER -

ID: 14946890