Relationship between local changes in cortical blood flow and extracellular K+ during spreading depression.
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Relationship between local changes in cortical blood flow and extracellular K+ during spreading depression. / Hansen, A J; Quistorff, B; Gjedde, A.
In: Acta physiologica Scandinavica, Vol. 109, No. 1, 1980, p. 1-6.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Relationship between local changes in cortical blood flow and extracellular K+ during spreading depression.
AU - Hansen, A J
AU - Quistorff, B
AU - Gjedde, A
PY - 1980
Y1 - 1980
N2 - Change of local cerebral blood flow in response to a single cortical spreading depression of Leão was studied in the brain. During a spreading depression, potassium briefly accumulates in the brain extracellular space. The cortical blood flow was normal during the maximal rate of increase of the extracellular potassium concentration. The blood flow doubled during the subsequent period of normalization of potassium and remained high for one minute thereafter. Thus, potassium cannot be the immediate mediator of the blood flow increase.
AB - Change of local cerebral blood flow in response to a single cortical spreading depression of Leão was studied in the brain. During a spreading depression, potassium briefly accumulates in the brain extracellular space. The cortical blood flow was normal during the maximal rate of increase of the extracellular potassium concentration. The blood flow doubled during the subsequent period of normalization of potassium and remained high for one minute thereafter. Thus, potassium cannot be the immediate mediator of the blood flow increase.
M3 - Journal article
C2 - 7446156
VL - 109
SP - 1
EP - 6
JO - Acta Physiologica Scandinavica
JF - Acta Physiologica Scandinavica
SN - 0001-6772
IS - 1
ER -
ID: 14944894