Standard
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care : Review and recommendations of the COSBID research group. / Dreier, Jens P; Fabricius, Martin; Ayata, Cenk; Sakowitz, Oliver W; William Shuttleworth, C; Dohmen, Christian; Graf, Rudolf; Vajkoczy, Peter; Helbok, Raimund; Suzuki, Michiyasu; Schiefecker, Alois J; Major, Sebastian; Winkler, Maren Kl; Kang, Eun-Jeung; Milakara, Denny; Oliveira-Ferreira, Ana I; Reiffurth, Clemens; Revankar, Gajanan S; Sugimoto, Kazutaka; Dengler, Nora F; Hecht, Nils; Foreman, Brandon; Feyen, Bart; Kondziella, Daniel; Friberg, Christian K; Piilgaard, Henning; Rosenthal, Eric S; Westover, M Brandon; Maslarova, Anna; Santos, Edgar; Hertle, Daniel; Sánchez-Porras, Renán; Jewell, Sharon L; Balança, Baptiste; Platz, Johannes; Hinzman, Jason M; Lückl, Janos; Schoknecht, Karl; Schöll, Michael; Drenckhahn, Christoph; Feuerstein, Delphine; Eriksen, Nina; Horst, Viktor; Bretz, Julia S; Jahnke, Paul; Scheel, Michael; Bohner, Georg; Rostrup, Egill; Pakkenberg, Bente; Heinemann, Uwe; Claassen, Jan; Carlson, Andrew P; Kowoll, Christina M; Lublinsky, Svetlana; Chassidim, Yoash; Shelef, Ilan; Friedman, Alon; Brinker, Gerrit; Reiner, Michael; Kirov, Sergei A; Andrew, R David; Farkas, Eszter; Güresir, Erdem; Vatter, Hartmut; Chung, Lee S; Brennan, K C; Lieutaud, Thomas; Marinesco, Stephane; Maas, Andrew Ir; Sahuquillo, Juan; Dahlem, Markus A; Richter, Frank; Herreras, Oscar; Boutelle, Martyn G; Okonkwo, David O; Bullock, M Ross; Witte, Otto W; Martus, Peter; van den Maagdenberg, Arn Mjm; Ferrari, Michel D; Dijkhuizen, Rick M; Shutter, Lori A; Andaluz, Norberto; Schulte, André P; MacVicar, Brian; Watanabe, Tomas; Woitzik, Johannes; Lauritzen, Martin; Strong, Anthony J; Hartings, Jed A.
In:
Journal of Cerebral Blood Flow and Metabolism, Vol. 37, No. 5, 05.2017, p. 1595-1625.
Research output: Contribution to journal › Review › Research › peer-review
Harvard
Dreier, JP, Fabricius, M, Ayata, C, Sakowitz, OW, William Shuttleworth, C, Dohmen, C, Graf, R, Vajkoczy, P, Helbok, R, Suzuki, M, Schiefecker, AJ, Major, S, Winkler, MK, Kang, E-J, Milakara, D, Oliveira-Ferreira, AI, Reiffurth, C, Revankar, GS, Sugimoto, K, Dengler, NF, Hecht, N, Foreman, B, Feyen, B
, Kondziella, D, Friberg, CK, Piilgaard, H, Rosenthal, ES, Westover, MB, Maslarova, A, Santos, E, Hertle, D, Sánchez-Porras, R, Jewell, SL, Balança, B, Platz, J, Hinzman, JM, Lückl, J, Schoknecht, K, Schöll, M, Drenckhahn, C, Feuerstein, D, Eriksen, N, Horst, V, Bretz, JS, Jahnke, P, Scheel, M, Bohner, G, Rostrup, E, Pakkenberg, B, Heinemann, U, Claassen, J, Carlson, AP, Kowoll, CM, Lublinsky, S, Chassidim, Y, Shelef, I, Friedman, A, Brinker, G, Reiner, M, Kirov, SA, Andrew, RD, Farkas, E, Güresir, E, Vatter, H, Chung, LS, Brennan, KC, Lieutaud, T, Marinesco, S, Maas, AI, Sahuquillo, J, Dahlem, MA, Richter, F, Herreras, O, Boutelle, MG, Okonkwo, DO, Bullock, MR, Witte, OW, Martus, P, van den Maagdenberg, AM, Ferrari, MD, Dijkhuizen, RM, Shutter, LA, Andaluz, N, Schulte, AP, MacVicar, B, Watanabe, T, Woitzik, J
, Lauritzen, M, Strong, AJ & Hartings, JA 2017, '
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group',
Journal of Cerebral Blood Flow and Metabolism, vol. 37, no. 5, pp. 1595-1625.
https://doi.org/10.1177/0271678X16654496
APA
Dreier, J. P., Fabricius, M., Ayata, C., Sakowitz, O. W., William Shuttleworth, C., Dohmen, C., Graf, R., Vajkoczy, P., Helbok, R., Suzuki, M., Schiefecker, A. J., Major, S., Winkler, M. K., Kang, E-J., Milakara, D., Oliveira-Ferreira, A. I., Reiffurth, C., Revankar, G. S., Sugimoto, K., ... Hartings, J. A. (2017).
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.
Journal of Cerebral Blood Flow and Metabolism,
37(5), 1595-1625.
https://doi.org/10.1177/0271678X16654496
Vancouver
Dreier JP, Fabricius M, Ayata C, Sakowitz OW, William Shuttleworth C, Dohmen C et al.
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.
Journal of Cerebral Blood Flow and Metabolism. 2017 May;37(5):1595-1625.
https://doi.org/10.1177/0271678X16654496
Author
Dreier, Jens P ; Fabricius, Martin ; Ayata, Cenk ; Sakowitz, Oliver W ; William Shuttleworth, C ; Dohmen, Christian ; Graf, Rudolf ; Vajkoczy, Peter ; Helbok, Raimund ; Suzuki, Michiyasu ; Schiefecker, Alois J ; Major, Sebastian ; Winkler, Maren Kl ; Kang, Eun-Jeung ; Milakara, Denny ; Oliveira-Ferreira, Ana I ; Reiffurth, Clemens ; Revankar, Gajanan S ; Sugimoto, Kazutaka ; Dengler, Nora F ; Hecht, Nils ; Foreman, Brandon ; Feyen, Bart ; Kondziella, Daniel ; Friberg, Christian K ; Piilgaard, Henning ; Rosenthal, Eric S ; Westover, M Brandon ; Maslarova, Anna ; Santos, Edgar ; Hertle, Daniel ; Sánchez-Porras, Renán ; Jewell, Sharon L ; Balança, Baptiste ; Platz, Johannes ; Hinzman, Jason M ; Lückl, Janos ; Schoknecht, Karl ; Schöll, Michael ; Drenckhahn, Christoph ; Feuerstein, Delphine ; Eriksen, Nina ; Horst, Viktor ; Bretz, Julia S ; Jahnke, Paul ; Scheel, Michael ; Bohner, Georg ; Rostrup, Egill ; Pakkenberg, Bente ; Heinemann, Uwe ; Claassen, Jan ; Carlson, Andrew P ; Kowoll, Christina M ; Lublinsky, Svetlana ; Chassidim, Yoash ; Shelef, Ilan ; Friedman, Alon ; Brinker, Gerrit ; Reiner, Michael ; Kirov, Sergei A ; Andrew, R David ; Farkas, Eszter ; Güresir, Erdem ; Vatter, Hartmut ; Chung, Lee S ; Brennan, K C ; Lieutaud, Thomas ; Marinesco, Stephane ; Maas, Andrew Ir ; Sahuquillo, Juan ; Dahlem, Markus A ; Richter, Frank ; Herreras, Oscar ; Boutelle, Martyn G ; Okonkwo, David O ; Bullock, M Ross ; Witte, Otto W ; Martus, Peter ; van den Maagdenberg, Arn Mjm ; Ferrari, Michel D ; Dijkhuizen, Rick M ; Shutter, Lori A ; Andaluz, Norberto ; Schulte, André P ; MacVicar, Brian ; Watanabe, Tomas ; Woitzik, Johannes ; Lauritzen, Martin ; Strong, Anthony J ; Hartings, Jed A. / Recording, analysis, and interpretation of spreading depolarizations in neurointensive care : Review and recommendations of the COSBID research group. In: Journal of Cerebral Blood Flow and Metabolism. 2017 ; Vol. 37, No. 5. pp. 1595-1625.
Bibtex
@article{cbd24a1b559d425589e5060f1fe9fb02,
title = "Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group",
abstract = "Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable cerebral gray matter, and are a crucial mechanism of lesion development. Spreading depolarizations are increasingly recorded during multimodal neuromonitoring in neurocritical care as a causal biomarker providing a diagnostic summary measure of metabolic failure and excitotoxic injury. Focal ischemia causes spreading depolarization within minutes. Further spreading depolarizations arise for hours to days due to energy supply-demand mismatch in viable tissue. Spreading depolarizations exacerbate neuronal injury through prolonged ionic breakdown and spreading depolarization-related hypoperfusion (spreading ischemia). Local duration of the depolarization indicates local tissue energy status and risk of injury. Regional electrocorticographic monitoring affords even remote detection of injury because spreading depolarizations propagate widely from ischemic or metabolically stressed zones; characteristic patterns, including temporal clusters of spreading depolarizations and persistent depression of spontaneous cortical activity, can be recognized and quantified. Here, we describe the experimental basis for interpreting these patterns and illustrate their translation to human disease. We further provide consensus recommendations for electrocorticographic methods to record, classify, and score spreading depolarizations and associated spreading depressions. These methods offer distinct advantages over other neuromonitoring modalities and allow for future refinement through less invasive and more automated approaches.",
author = "Dreier, {Jens P} and Martin Fabricius and Cenk Ayata and Sakowitz, {Oliver W} and {William Shuttleworth}, C and Christian Dohmen and Rudolf Graf and Peter Vajkoczy and Raimund Helbok and Michiyasu Suzuki and Schiefecker, {Alois J} and Sebastian Major and Winkler, {Maren Kl} and Eun-Jeung Kang and Denny Milakara and Oliveira-Ferreira, {Ana I} and Clemens Reiffurth and Revankar, {Gajanan S} and Kazutaka Sugimoto and Dengler, {Nora F} and Nils Hecht and Brandon Foreman and Bart Feyen and Daniel Kondziella and Friberg, {Christian K} and Henning Piilgaard and Rosenthal, {Eric S} and Westover, {M Brandon} and Anna Maslarova and Edgar Santos and Daniel Hertle and Ren{\'a}n S{\'a}nchez-Porras and Jewell, {Sharon L} and Baptiste Balan{\c c}a and Johannes Platz and Hinzman, {Jason M} and Janos L{\"u}ckl and Karl Schoknecht and Michael Sch{\"o}ll and Christoph Drenckhahn and Delphine Feuerstein and Nina Eriksen and Viktor Horst and Bretz, {Julia S} and Paul Jahnke and Michael Scheel and Georg Bohner and Egill Rostrup and Bente Pakkenberg and Uwe Heinemann and Jan Claassen and Carlson, {Andrew P} and Kowoll, {Christina M} and Svetlana Lublinsky and Yoash Chassidim and Ilan Shelef and Alon Friedman and Gerrit Brinker and Michael Reiner and Kirov, {Sergei A} and Andrew, {R David} and Eszter Farkas and Erdem G{\"u}resir and Hartmut Vatter and Chung, {Lee S} and Brennan, {K C} and Thomas Lieutaud and Stephane Marinesco and Maas, {Andrew Ir} and Juan Sahuquillo and Dahlem, {Markus A} and Frank Richter and Oscar Herreras and Boutelle, {Martyn G} and Okonkwo, {David O} and Bullock, {M Ross} and Witte, {Otto W} and Peter Martus and {van den Maagdenberg}, {Arn Mjm} and Ferrari, {Michel D} and Dijkhuizen, {Rick M} and Shutter, {Lori A} and Norberto Andaluz and Schulte, {Andr{\'e} P} and Brian MacVicar and Tomas Watanabe and Johannes Woitzik and Martin Lauritzen and Strong, {Anthony J} and Hartings, {Jed A}",
note = "{\textcopyright} The Author(s) 2016.",
year = "2017",
month = may,
doi = "10.1177/0271678X16654496",
language = "English",
volume = "37",
pages = "1595--1625",
journal = "Journal of Cerebral Blood Flow and Metabolism",
issn = "0271-678X",
publisher = "SAGE Publications",
number = "5",
}
RIS
TY - JOUR
T1 - Recording, analysis, and interpretation of spreading depolarizations in neurointensive care
T2 - Review and recommendations of the COSBID research group
AU - Dreier, Jens P
AU - Fabricius, Martin
AU - Ayata, Cenk
AU - Sakowitz, Oliver W
AU - William Shuttleworth, C
AU - Dohmen, Christian
AU - Graf, Rudolf
AU - Vajkoczy, Peter
AU - Helbok, Raimund
AU - Suzuki, Michiyasu
AU - Schiefecker, Alois J
AU - Major, Sebastian
AU - Winkler, Maren Kl
AU - Kang, Eun-Jeung
AU - Milakara, Denny
AU - Oliveira-Ferreira, Ana I
AU - Reiffurth, Clemens
AU - Revankar, Gajanan S
AU - Sugimoto, Kazutaka
AU - Dengler, Nora F
AU - Hecht, Nils
AU - Foreman, Brandon
AU - Feyen, Bart
AU - Kondziella, Daniel
AU - Friberg, Christian K
AU - Piilgaard, Henning
AU - Rosenthal, Eric S
AU - Westover, M Brandon
AU - Maslarova, Anna
AU - Santos, Edgar
AU - Hertle, Daniel
AU - Sánchez-Porras, Renán
AU - Jewell, Sharon L
AU - Balança, Baptiste
AU - Platz, Johannes
AU - Hinzman, Jason M
AU - Lückl, Janos
AU - Schoknecht, Karl
AU - Schöll, Michael
AU - Drenckhahn, Christoph
AU - Feuerstein, Delphine
AU - Eriksen, Nina
AU - Horst, Viktor
AU - Bretz, Julia S
AU - Jahnke, Paul
AU - Scheel, Michael
AU - Bohner, Georg
AU - Rostrup, Egill
AU - Pakkenberg, Bente
AU - Heinemann, Uwe
AU - Claassen, Jan
AU - Carlson, Andrew P
AU - Kowoll, Christina M
AU - Lublinsky, Svetlana
AU - Chassidim, Yoash
AU - Shelef, Ilan
AU - Friedman, Alon
AU - Brinker, Gerrit
AU - Reiner, Michael
AU - Kirov, Sergei A
AU - Andrew, R David
AU - Farkas, Eszter
AU - Güresir, Erdem
AU - Vatter, Hartmut
AU - Chung, Lee S
AU - Brennan, K C
AU - Lieutaud, Thomas
AU - Marinesco, Stephane
AU - Maas, Andrew Ir
AU - Sahuquillo, Juan
AU - Dahlem, Markus A
AU - Richter, Frank
AU - Herreras, Oscar
AU - Boutelle, Martyn G
AU - Okonkwo, David O
AU - Bullock, M Ross
AU - Witte, Otto W
AU - Martus, Peter
AU - van den Maagdenberg, Arn Mjm
AU - Ferrari, Michel D
AU - Dijkhuizen, Rick M
AU - Shutter, Lori A
AU - Andaluz, Norberto
AU - Schulte, André P
AU - MacVicar, Brian
AU - Watanabe, Tomas
AU - Woitzik, Johannes
AU - Lauritzen, Martin
AU - Strong, Anthony J
AU - Hartings, Jed A
N1 - © The Author(s) 2016.
PY - 2017/5
Y1 - 2017/5
N2 - Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable cerebral gray matter, and are a crucial mechanism of lesion development. Spreading depolarizations are increasingly recorded during multimodal neuromonitoring in neurocritical care as a causal biomarker providing a diagnostic summary measure of metabolic failure and excitotoxic injury. Focal ischemia causes spreading depolarization within minutes. Further spreading depolarizations arise for hours to days due to energy supply-demand mismatch in viable tissue. Spreading depolarizations exacerbate neuronal injury through prolonged ionic breakdown and spreading depolarization-related hypoperfusion (spreading ischemia). Local duration of the depolarization indicates local tissue energy status and risk of injury. Regional electrocorticographic monitoring affords even remote detection of injury because spreading depolarizations propagate widely from ischemic or metabolically stressed zones; characteristic patterns, including temporal clusters of spreading depolarizations and persistent depression of spontaneous cortical activity, can be recognized and quantified. Here, we describe the experimental basis for interpreting these patterns and illustrate their translation to human disease. We further provide consensus recommendations for electrocorticographic methods to record, classify, and score spreading depolarizations and associated spreading depressions. These methods offer distinct advantages over other neuromonitoring modalities and allow for future refinement through less invasive and more automated approaches.
AB - Spreading depolarizations (SD) are waves of abrupt, near-complete breakdown of neuronal transmembrane ion gradients, are the largest possible pathophysiologic disruption of viable cerebral gray matter, and are a crucial mechanism of lesion development. Spreading depolarizations are increasingly recorded during multimodal neuromonitoring in neurocritical care as a causal biomarker providing a diagnostic summary measure of metabolic failure and excitotoxic injury. Focal ischemia causes spreading depolarization within minutes. Further spreading depolarizations arise for hours to days due to energy supply-demand mismatch in viable tissue. Spreading depolarizations exacerbate neuronal injury through prolonged ionic breakdown and spreading depolarization-related hypoperfusion (spreading ischemia). Local duration of the depolarization indicates local tissue energy status and risk of injury. Regional electrocorticographic monitoring affords even remote detection of injury because spreading depolarizations propagate widely from ischemic or metabolically stressed zones; characteristic patterns, including temporal clusters of spreading depolarizations and persistent depression of spontaneous cortical activity, can be recognized and quantified. Here, we describe the experimental basis for interpreting these patterns and illustrate their translation to human disease. We further provide consensus recommendations for electrocorticographic methods to record, classify, and score spreading depolarizations and associated spreading depressions. These methods offer distinct advantages over other neuromonitoring modalities and allow for future refinement through less invasive and more automated approaches.
U2 - 10.1177/0271678X16654496
DO - 10.1177/0271678X16654496
M3 - Review
C2 - 27317657
VL - 37
SP - 1595
EP - 1625
JO - Journal of Cerebral Blood Flow and Metabolism
JF - Journal of Cerebral Blood Flow and Metabolism
SN - 0271-678X
IS - 5
ER -