Proteomics of the photoneuroendocrine circadian system of the brain

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Proteomics of the photoneuroendocrine circadian system of the brain. / Møller, Morten; Lund-Andersen, Casper; Rovsing, Louise; Sparre, Thomas; Bache, Nicolai; Roepstorff, Peter; Vorum, Henrik.

In: Mass Spectrometry Reviews, Vol. 29, No. 2, 2010, p. 313-25.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Møller, M, Lund-Andersen, C, Rovsing, L, Sparre, T, Bache, N, Roepstorff, P & Vorum, H 2010, 'Proteomics of the photoneuroendocrine circadian system of the brain', Mass Spectrometry Reviews, vol. 29, no. 2, pp. 313-25. https://doi.org/10.1002/mas.20237

APA

Møller, M., Lund-Andersen, C., Rovsing, L., Sparre, T., Bache, N., Roepstorff, P., & Vorum, H. (2010). Proteomics of the photoneuroendocrine circadian system of the brain. Mass Spectrometry Reviews, 29(2), 313-25. https://doi.org/10.1002/mas.20237

Vancouver

Møller M, Lund-Andersen C, Rovsing L, Sparre T, Bache N, Roepstorff P et al. Proteomics of the photoneuroendocrine circadian system of the brain. Mass Spectrometry Reviews. 2010;29(2):313-25. https://doi.org/10.1002/mas.20237

Author

Møller, Morten ; Lund-Andersen, Casper ; Rovsing, Louise ; Sparre, Thomas ; Bache, Nicolai ; Roepstorff, Peter ; Vorum, Henrik. / Proteomics of the photoneuroendocrine circadian system of the brain. In: Mass Spectrometry Reviews. 2010 ; Vol. 29, No. 2. pp. 313-25.

Bibtex

@article{de761818fc7c4a0d9b986953a0117624,
title = "Proteomics of the photoneuroendocrine circadian system of the brain",
abstract = "The photoneuroendocrine circadian system of the brain consists of (a) specialized photoreceptors in the retina, (b) a circadian generator located in the forebrain that contains {"}clock genes,{"} (c) specialized nuclei in the forebrain involved in neuroendocrine secretion, and (d) the pineal gland. The circadian generator is a nucleus, called the suprachiasmatic nucleus (SCN). The neurons of this nucleus contain {"}clock genes,{"} the transcription of which exhibits a circadian rhythm. Most circadian rhythms are generated by the neurons of this nucleus and, via neuronal and humoral connections, the SCN controls circadian activity of the brain and peripheral tissues. The endogenous oscillator of the SCN is each day entrained to the length of the daily photoperiod by light that reach the retina, and specialized photoreceptors transmit impulses to the SCN via the optic nerves. Mass screening for day/night variations in gene expression in the circadian system as well as in the whole brain and peripheral tissues have, during the last decade, been performed. However, studies of circadian changes in the proteome have been less investigated. In this survey, the anatomy and function of the circadian-generating system in mammals is described, and recent proteomic studies that investigate day/night changes in the retina, SCN, and pineal gland are reviewed. Further circadian changes controlled by the SCN in gene and protein expression in the liver are discussed.",
keywords = "Animals, Brain, Circadian Rhythm, Humans, Neurosecretory Systems, Photoperiod, Proteome",
author = "Morten M{\o}ller and Casper Lund-Andersen and Louise Rovsing and Thomas Sparre and Nicolai Bache and Peter Roepstorff and Henrik Vorum",
note = "Copyright 2009 Wiley Periodicals, Inc.",
year = "2010",
doi = "10.1002/mas.20237",
language = "English",
volume = "29",
pages = "313--25",
journal = "Mass Spectrometry Reviews",
issn = "0277-7037",
publisher = "JohnWiley & Sons, Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Proteomics of the photoneuroendocrine circadian system of the brain

AU - Møller, Morten

AU - Lund-Andersen, Casper

AU - Rovsing, Louise

AU - Sparre, Thomas

AU - Bache, Nicolai

AU - Roepstorff, Peter

AU - Vorum, Henrik

N1 - Copyright 2009 Wiley Periodicals, Inc.

PY - 2010

Y1 - 2010

N2 - The photoneuroendocrine circadian system of the brain consists of (a) specialized photoreceptors in the retina, (b) a circadian generator located in the forebrain that contains "clock genes," (c) specialized nuclei in the forebrain involved in neuroendocrine secretion, and (d) the pineal gland. The circadian generator is a nucleus, called the suprachiasmatic nucleus (SCN). The neurons of this nucleus contain "clock genes," the transcription of which exhibits a circadian rhythm. Most circadian rhythms are generated by the neurons of this nucleus and, via neuronal and humoral connections, the SCN controls circadian activity of the brain and peripheral tissues. The endogenous oscillator of the SCN is each day entrained to the length of the daily photoperiod by light that reach the retina, and specialized photoreceptors transmit impulses to the SCN via the optic nerves. Mass screening for day/night variations in gene expression in the circadian system as well as in the whole brain and peripheral tissues have, during the last decade, been performed. However, studies of circadian changes in the proteome have been less investigated. In this survey, the anatomy and function of the circadian-generating system in mammals is described, and recent proteomic studies that investigate day/night changes in the retina, SCN, and pineal gland are reviewed. Further circadian changes controlled by the SCN in gene and protein expression in the liver are discussed.

AB - The photoneuroendocrine circadian system of the brain consists of (a) specialized photoreceptors in the retina, (b) a circadian generator located in the forebrain that contains "clock genes," (c) specialized nuclei in the forebrain involved in neuroendocrine secretion, and (d) the pineal gland. The circadian generator is a nucleus, called the suprachiasmatic nucleus (SCN). The neurons of this nucleus contain "clock genes," the transcription of which exhibits a circadian rhythm. Most circadian rhythms are generated by the neurons of this nucleus and, via neuronal and humoral connections, the SCN controls circadian activity of the brain and peripheral tissues. The endogenous oscillator of the SCN is each day entrained to the length of the daily photoperiod by light that reach the retina, and specialized photoreceptors transmit impulses to the SCN via the optic nerves. Mass screening for day/night variations in gene expression in the circadian system as well as in the whole brain and peripheral tissues have, during the last decade, been performed. However, studies of circadian changes in the proteome have been less investigated. In this survey, the anatomy and function of the circadian-generating system in mammals is described, and recent proteomic studies that investigate day/night changes in the retina, SCN, and pineal gland are reviewed. Further circadian changes controlled by the SCN in gene and protein expression in the liver are discussed.

KW - Animals

KW - Brain

KW - Circadian Rhythm

KW - Humans

KW - Neurosecretory Systems

KW - Photoperiod

KW - Proteome

U2 - 10.1002/mas.20237

DO - 10.1002/mas.20237

M3 - Journal article

C2 - 19437489

VL - 29

SP - 313

EP - 325

JO - Mass Spectrometry Reviews

JF - Mass Spectrometry Reviews

SN - 0277-7037

IS - 2

ER -

ID: 33854995