Pineal function: impact of microarray analysis
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Pineal function: impact of microarray analysis. / Klein, David C; Bailey, Michael J; Carter, David A; Kim, Jong-so; Shi, Qiong; Ho, Anthony K; Chik, Constance L; Gaildrat, Pascaline; Morin, Fabrice; Ganguly, Surajit; Rath, Martin F; Møller, Morten; Sugden, David; Rangel, Zoila G; Munson, Peter J; Weller, Joan L; Coon, Steven L.
In: Molecular and Cellular Endocrinology, Vol. 314, No. 2, 2009, p. 170-83.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Pineal function: impact of microarray analysis
AU - Klein, David C
AU - Bailey, Michael J
AU - Carter, David A
AU - Kim, Jong-so
AU - Shi, Qiong
AU - Ho, Anthony K
AU - Chik, Constance L
AU - Gaildrat, Pascaline
AU - Morin, Fabrice
AU - Ganguly, Surajit
AU - Rath, Martin F
AU - Møller, Morten
AU - Sugden, David
AU - Rangel, Zoila G
AU - Munson, Peter J
AU - Weller, Joan L
AU - Coon, Steven L
N1 - Keywords: Animals; Circadian Rhythm; Humans; Melatonin; Neurons; Oligonucleotide Array Sequence Analysis; Pineal Gland; Signal Transduction
PY - 2009
Y1 - 2009
N2 - Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.
AB - Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.
U2 - 10.1016/j.mce.2009.07.010
DO - 10.1016/j.mce.2009.07.010
M3 - Journal article
C2 - 19622385
VL - 314
SP - 170
EP - 183
JO - Molecular and Cellular Endocrinology
JF - Molecular and Cellular Endocrinology
SN - 0303-7207
IS - 2
ER -
ID: 18791013