Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide. / Nordgaard, Julie C; Kruse, Lars S; Møller, Morten; Kruuse, Christina.

In: Cephalalgia : an international journal of headache, Vol. 34, No. 7, 09.12.2014, p. 503-513.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nordgaard, JC, Kruse, LS, Møller, M & Kruuse, C 2014, 'Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide', Cephalalgia : an international journal of headache, vol. 34, no. 7, pp. 503-513. https://doi.org/10.1177/0333102413515345

APA

Nordgaard, J. C., Kruse, L. S., Møller, M., & Kruuse, C. (2014). Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide. Cephalalgia : an international journal of headache, 34(7), 503-513. https://doi.org/10.1177/0333102413515345

Vancouver

Nordgaard JC, Kruse LS, Møller M, Kruuse C. Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide. Cephalalgia : an international journal of headache. 2014 Dec 9;34(7):503-513. https://doi.org/10.1177/0333102413515345

Author

Nordgaard, Julie C ; Kruse, Lars S ; Møller, Morten ; Kruuse, Christina. / Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide. In: Cephalalgia : an international journal of headache. 2014 ; Vol. 34, No. 7. pp. 503-513.

Bibtex

@article{d6941561605649a984e8217c0bd07451,
title = "Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide",
abstract = "Understanding of the neuropathology leading to migraine pain has centered on either a vascular or neuronal origin. Sildenafil, a specific inhibitor of phosphodiesterase 5 (PDE5), induces migraine-like headache in a human headache model without concomitant artery dilation. The presence and activity of PDE3 and PDE5 is known in cerebral arteries. However, the presence in the neuronal part of the trigeminovascular pathway, i.e. the trigeminal ganglion and the possible co-localization with calcitonin gene-related peptide (CGRP), is not known.",
author = "Nordgaard, {Julie C} and Kruse, {Lars S} and Morten M{\o}ller and Christina Kruuse",
year = "2014",
month = dec,
day = "9",
doi = "10.1177/0333102413515345",
language = "English",
volume = "34",
pages = "503--513",
journal = "Cephalalgia",
issn = "0800-1952",
publisher = "SAGE Publications",
number = "7",

}

RIS

TY - JOUR

T1 - Phosphodiesterases 3 and 5 express activity in the trigeminal ganglion and co-localize with calcitonin gene-related peptide

AU - Nordgaard, Julie C

AU - Kruse, Lars S

AU - Møller, Morten

AU - Kruuse, Christina

PY - 2014/12/9

Y1 - 2014/12/9

N2 - Understanding of the neuropathology leading to migraine pain has centered on either a vascular or neuronal origin. Sildenafil, a specific inhibitor of phosphodiesterase 5 (PDE5), induces migraine-like headache in a human headache model without concomitant artery dilation. The presence and activity of PDE3 and PDE5 is known in cerebral arteries. However, the presence in the neuronal part of the trigeminovascular pathway, i.e. the trigeminal ganglion and the possible co-localization with calcitonin gene-related peptide (CGRP), is not known.

AB - Understanding of the neuropathology leading to migraine pain has centered on either a vascular or neuronal origin. Sildenafil, a specific inhibitor of phosphodiesterase 5 (PDE5), induces migraine-like headache in a human headache model without concomitant artery dilation. The presence and activity of PDE3 and PDE5 is known in cerebral arteries. However, the presence in the neuronal part of the trigeminovascular pathway, i.e. the trigeminal ganglion and the possible co-localization with calcitonin gene-related peptide (CGRP), is not known.

U2 - 10.1177/0333102413515345

DO - 10.1177/0333102413515345

M3 - Journal article

C2 - 24322481

VL - 34

SP - 503

EP - 513

JO - Cephalalgia

JF - Cephalalgia

SN - 0800-1952

IS - 7

ER -

ID: 106812975