Metabolic effect of topical application of metrizamide to rat brain cortex.

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Standard

Metabolic effect of topical application of metrizamide to rat brain cortex. / Bech, L; Diemer, N H; Gjedde, A.

In: Acta Neurologica Scandinavica, Vol. 72, No. 4, 1985, p. 427-31.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Bech, L, Diemer, NH & Gjedde, A 1985, 'Metabolic effect of topical application of metrizamide to rat brain cortex.', Acta Neurologica Scandinavica, vol. 72, no. 4, pp. 427-31.

APA

Bech, L., Diemer, N. H., & Gjedde, A. (1985). Metabolic effect of topical application of metrizamide to rat brain cortex. Acta Neurologica Scandinavica, 72(4), 427-31.

Vancouver

Bech L, Diemer NH, Gjedde A. Metabolic effect of topical application of metrizamide to rat brain cortex. Acta Neurologica Scandinavica. 1985;72(4):427-31.

Author

Bech, L ; Diemer, N H ; Gjedde, A. / Metabolic effect of topical application of metrizamide to rat brain cortex. In: Acta Neurologica Scandinavica. 1985 ; Vol. 72, No. 4. pp. 427-31.

Bibtex

@article{2db7f810b31511debc73000ea68e967b,
title = "Metabolic effect of topical application of metrizamide to rat brain cortex.",
abstract = "The x-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation both in vitro and in vivo. in vivo. In vivo, however, the present autoradiographic study with labeled 2-deoxyglucose revealed a local increase of glucose metabolic rate in an area of direct metrizamide application to the cerebral cortex. The local increase was 137% above the metabolic rate calculated for the contralateral region. Regions outside the application site showed no difference between the glucose metabolic rates of the ipsi- and contralateral hemispheres. Evidence from the literature suggests that metrizamide may stimulate cortical activity by inhibiting acetylcholinesterase.",
author = "L Bech and Diemer, {N H} and A Gjedde",
year = "1985",
language = "English",
volume = "72",
pages = "427--31",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Metabolic effect of topical application of metrizamide to rat brain cortex.

AU - Bech, L

AU - Diemer, N H

AU - Gjedde, A

PY - 1985

Y1 - 1985

N2 - The x-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation both in vitro and in vivo. in vivo. In vivo, however, the present autoradiographic study with labeled 2-deoxyglucose revealed a local increase of glucose metabolic rate in an area of direct metrizamide application to the cerebral cortex. The local increase was 137% above the metabolic rate calculated for the contralateral region. Regions outside the application site showed no difference between the glucose metabolic rates of the ipsi- and contralateral hemispheres. Evidence from the literature suggests that metrizamide may stimulate cortical activity by inhibiting acetylcholinesterase.

AB - The x-ray contrast material metrizamide is structurally related to 2-deoxyglucose and inhibits brain glucose phosphorylation both in vitro and in vivo. in vivo. In vivo, however, the present autoradiographic study with labeled 2-deoxyglucose revealed a local increase of glucose metabolic rate in an area of direct metrizamide application to the cerebral cortex. The local increase was 137% above the metabolic rate calculated for the contralateral region. Regions outside the application site showed no difference between the glucose metabolic rates of the ipsi- and contralateral hemispheres. Evidence from the literature suggests that metrizamide may stimulate cortical activity by inhibiting acetylcholinesterase.

M3 - Journal article

C2 - 4082908

VL - 72

SP - 427

EP - 431

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 4

ER -

ID: 14945631