Magnetic field associated with spreading depression: a model for the detection of migraine
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Magnetic field associated with spreading depression : a model for the detection of migraine. / Okada, Yoshio C.; Lauritzen, Martin; Nicholson, Charles.
In: Brain Research, Vol. 442, No. 1, 23.02.1988, p. 185-190.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Magnetic field associated with spreading depression
T2 - a model for the detection of migraine
AU - Okada, Yoshio C.
AU - Lauritzen, Martin
AU - Nicholson, Charles
PY - 1988/2/23
Y1 - 1988/2/23
N2 - Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.
AB - Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.
KW - Biomagnetism
KW - Cerebellum
KW - Evoked magnetic field
KW - Migraine
KW - Spreading depression
UR - http://www.scopus.com/inward/record.url?scp=0023845478&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(88)91450-3
DO - 10.1016/0006-8993(88)91450-3
M3 - Journal article
C2 - 3359253
AN - SCOPUS:0023845478
VL - 442
SP - 185
EP - 190
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1
ER -
ID: 201456543