Intrinsic membrane properties causing a bistable behaviour of α-motoneurones

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Intrinsic membrane properties causing a bistable behaviour of α-motoneurones. / Hounsgaard, J.; Hultborn, H.; Jespersen, B.; Kiehn, O.

In: Experimental Brain Research, Vol. 55, No. 2, 01.06.1984, p. 391-394.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Hounsgaard, J, Hultborn, H, Jespersen, B & Kiehn, O 1984, 'Intrinsic membrane properties causing a bistable behaviour of α-motoneurones', Experimental Brain Research, vol. 55, no. 2, pp. 391-394. https://doi.org/10.1007/BF00237290

APA

Hounsgaard, J., Hultborn, H., Jespersen, B., & Kiehn, O. (1984). Intrinsic membrane properties causing a bistable behaviour of α-motoneurones. Experimental Brain Research, 55(2), 391-394. https://doi.org/10.1007/BF00237290

Vancouver

Hounsgaard J, Hultborn H, Jespersen B, Kiehn O. Intrinsic membrane properties causing a bistable behaviour of α-motoneurones. Experimental Brain Research. 1984 Jun 1;55(2):391-394. https://doi.org/10.1007/BF00237290

Author

Hounsgaard, J. ; Hultborn, H. ; Jespersen, B. ; Kiehn, O. / Intrinsic membrane properties causing a bistable behaviour of α-motoneurones. In: Experimental Brain Research. 1984 ; Vol. 55, No. 2. pp. 391-394.

Bibtex

@article{7166667d7bfe4231a5a6f26ccd8f6eca,
title = "Intrinsic membrane properties causing a bistable behaviour of α-motoneurones",
abstract = "In decerebrate cats a train of impulses in Ia afferents may lead to a sustained increase in excitability of α-motoneurones of homonymous and heteronymous muscles. It was previously suggested that this long-lasting excitability increase reflects a maintained synaptic input to the motoneurones from excitatory interneurones. With intracellular recording from motoneurones we here demonstrate that the sustained increase of α-motoneurone activity is due to an all-or-none plateau depolarization. This plateau can be induced by a short train of excitatory synaptic potentials or a brief, intracellularly injected depolarizing current pulse and is terminated by a short train of inhibitory synaptic potentials or a hyperpolarizing current pulse. It is concluded that maintained motor unit firing triggered by a brief train of impulses in Ia afferent reflects an intrinsic bistable behaviour of α-motoneurones.",
keywords = "Bistable state, Motoneurones, Serotonin, Spinal cord",
author = "J. Hounsgaard and H. Hultborn and B. Jespersen and O. Kiehn",
year = "1984",
month = jun,
day = "1",
doi = "10.1007/BF00237290",
language = "English",
volume = "55",
pages = "391--394",
journal = "Experimental Brain Research",
issn = "0014-4819",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Intrinsic membrane properties causing a bistable behaviour of α-motoneurones

AU - Hounsgaard, J.

AU - Hultborn, H.

AU - Jespersen, B.

AU - Kiehn, O.

PY - 1984/6/1

Y1 - 1984/6/1

N2 - In decerebrate cats a train of impulses in Ia afferents may lead to a sustained increase in excitability of α-motoneurones of homonymous and heteronymous muscles. It was previously suggested that this long-lasting excitability increase reflects a maintained synaptic input to the motoneurones from excitatory interneurones. With intracellular recording from motoneurones we here demonstrate that the sustained increase of α-motoneurone activity is due to an all-or-none plateau depolarization. This plateau can be induced by a short train of excitatory synaptic potentials or a brief, intracellularly injected depolarizing current pulse and is terminated by a short train of inhibitory synaptic potentials or a hyperpolarizing current pulse. It is concluded that maintained motor unit firing triggered by a brief train of impulses in Ia afferent reflects an intrinsic bistable behaviour of α-motoneurones.

AB - In decerebrate cats a train of impulses in Ia afferents may lead to a sustained increase in excitability of α-motoneurones of homonymous and heteronymous muscles. It was previously suggested that this long-lasting excitability increase reflects a maintained synaptic input to the motoneurones from excitatory interneurones. With intracellular recording from motoneurones we here demonstrate that the sustained increase of α-motoneurone activity is due to an all-or-none plateau depolarization. This plateau can be induced by a short train of excitatory synaptic potentials or a brief, intracellularly injected depolarizing current pulse and is terminated by a short train of inhibitory synaptic potentials or a hyperpolarizing current pulse. It is concluded that maintained motor unit firing triggered by a brief train of impulses in Ia afferent reflects an intrinsic bistable behaviour of α-motoneurones.

KW - Bistable state

KW - Motoneurones

KW - Serotonin

KW - Spinal cord

UR - http://www.scopus.com/inward/record.url?scp=0021258738&partnerID=8YFLogxK

U2 - 10.1007/BF00237290

DO - 10.1007/BF00237290

M3 - Journal article

C2 - 6086378

AN - SCOPUS:0021258738

VL - 55

SP - 391

EP - 394

JO - Experimental Brain Research

JF - Experimental Brain Research

SN - 0014-4819

IS - 2

ER -

ID: 194981226