Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface
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Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface. / Meneghetti, Marcello; Sui, Kunyang; Kaur, Jaspreet; Sørensen, Roar Jakob Fleng ; Berg, Rune W.; Markos, Christos.
Optogenetics and Optical Manipulation 2023: Proceedings. Vol. 12366 SPIE--The International Society for Optical Engineering, 2023. p. 13-18 1236605.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - Infrared neural stimulation and electrophysiology in a soft fiber-based neural interface
AU - Meneghetti, Marcello
AU - Sui, Kunyang
AU - Kaur, Jaspreet
AU - Sørensen, Roar Jakob Fleng
AU - Berg, Rune W.
AU - Markos, Christos
PY - 2023
Y1 - 2023
N2 - Infrared neurostimulation has emerged in recent years as a promising technique for controlling neuronal activity without genetic manipulation. Having high absorption of the employed wavelengths as its fundamental mechanism, it requires implantable platforms to deliver light in brain regions deeper than the first cortical layers. Due to the spatial confinement of the stimulation, electrodes integrated in close proximity to the illumination spot are desirable to verify the effects of the stimulation by extracellular electrophysiology. Here we developed and validated in vivo a multifunctional neural interface based on a soft, biocompatible polymer optical fiber that allows simultaneous infrared neurostimulation and electrophysiology.
AB - Infrared neurostimulation has emerged in recent years as a promising technique for controlling neuronal activity without genetic manipulation. Having high absorption of the employed wavelengths as its fundamental mechanism, it requires implantable platforms to deliver light in brain regions deeper than the first cortical layers. Due to the spatial confinement of the stimulation, electrodes integrated in close proximity to the illumination spot are desirable to verify the effects of the stimulation by extracellular electrophysiology. Here we developed and validated in vivo a multifunctional neural interface based on a soft, biocompatible polymer optical fiber that allows simultaneous infrared neurostimulation and electrophysiology.
U2 - 10.1117/12.2646177
DO - 10.1117/12.2646177
M3 - Book chapter
VL - 12366
SP - 13
EP - 18
BT - Optogenetics and Optical Manipulation 2023
PB - SPIE--The International Society for Optical Engineering
Y2 - 28 January 2023 through 3 February 2023
ER -
ID: 340226178