Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness. / Geertsen, Svend Sparre; Kirk, Henrik; Lorentzen, Jakob; Jorsal, Martin; Johansson, Claus Bo; Nielsen, Jens Bo.

In: Clinical Neurophysiology, Vol. 126, No. 12, 2015, p. 2320-2329.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Geertsen, SS, Kirk, H, Lorentzen, J, Jorsal, M, Johansson, CB & Nielsen, JB 2015, 'Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness', Clinical Neurophysiology, vol. 126, no. 12, pp. 2320-2329. https://doi.org/10.1016/j.clinph.2015.02.005

APA

Geertsen, S. S., Kirk, H., Lorentzen, J., Jorsal, M., Johansson, C. B., & Nielsen, J. B. (2015). Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness. Clinical Neurophysiology, 126(12), 2320-2329. https://doi.org/10.1016/j.clinph.2015.02.005

Vancouver

Geertsen SS, Kirk H, Lorentzen J, Jorsal M, Johansson CB, Nielsen JB. Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness. Clinical Neurophysiology. 2015;126(12):2320-2329. https://doi.org/10.1016/j.clinph.2015.02.005

Author

Geertsen, Svend Sparre ; Kirk, Henrik ; Lorentzen, Jakob ; Jorsal, Martin ; Johansson, Claus Bo ; Nielsen, Jens Bo. / Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness. In: Clinical Neurophysiology. 2015 ; Vol. 126, No. 12. pp. 2320-2329.

Bibtex

@article{e7d7f9d2d04648d3b89745571315d7d5,
title = "Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness",
abstract = "OBJECTIVE: It is still not clarified whether spasticity contributes to impairments of gait function. Here we compared biomechanical measures of muscle weakness and stiffness of ankle muscles to impairments of gait function in adults with cerebral palsy (CP).METHODS: Twenty-four adults with CP (mean age 34.3, range 18-57years) and fifteen healthy age-matched controls were biomechanically measured for passive and reflex-mediated stiffness of the ankle plantarflexors at rest, maximal voluntary plantarflexion and dorsiflexion effort (MVCpf,df) and rate of force development (RFDpf,df). Kinematic analysis of the ankle joint during treadmill walking was obtained by 3-D motion analysis.RESULTS: Passive stiffness was significantly increased in adults with CP compared to controls. Passive stiffness and RFDdf were correlated to reduced toe lift. RFDpf provided the best correlation to push-off velocity, range of movement in the ankle joint and gait speed. Reflex-mediated stiffness was not correlated to any parameters of impaired gait.CONCLUSIONS: Impaired gait function in adults with CP is associated with reduced RFD and increased passive stiffness of ankle muscles.SIGNIFICANCE: These findings suggest that reduced rapid force generation and increased passive stiffness of ankle muscles rather than increased reflex-mediated stiffness (spasticity) likely contributes to impaired gait function in adults with CP.",
author = "Geertsen, {Svend Sparre} and Henrik Kirk and Jakob Lorentzen and Martin Jorsal and Johansson, {Claus Bo} and Nielsen, {Jens Bo}",
note = "CURIS 2015 NEXS 102",
year = "2015",
doi = "10.1016/j.clinph.2015.02.005",
language = "English",
volume = "126",
pages = "2320--2329",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd",
number = "12",

}

RIS

TY - JOUR

T1 - Impaired gait function in adults with cerebral palsy is associated with reduced rapid force generation and increased passive stiffness

AU - Geertsen, Svend Sparre

AU - Kirk, Henrik

AU - Lorentzen, Jakob

AU - Jorsal, Martin

AU - Johansson, Claus Bo

AU - Nielsen, Jens Bo

N1 - CURIS 2015 NEXS 102

PY - 2015

Y1 - 2015

N2 - OBJECTIVE: It is still not clarified whether spasticity contributes to impairments of gait function. Here we compared biomechanical measures of muscle weakness and stiffness of ankle muscles to impairments of gait function in adults with cerebral palsy (CP).METHODS: Twenty-four adults with CP (mean age 34.3, range 18-57years) and fifteen healthy age-matched controls were biomechanically measured for passive and reflex-mediated stiffness of the ankle plantarflexors at rest, maximal voluntary plantarflexion and dorsiflexion effort (MVCpf,df) and rate of force development (RFDpf,df). Kinematic analysis of the ankle joint during treadmill walking was obtained by 3-D motion analysis.RESULTS: Passive stiffness was significantly increased in adults with CP compared to controls. Passive stiffness and RFDdf were correlated to reduced toe lift. RFDpf provided the best correlation to push-off velocity, range of movement in the ankle joint and gait speed. Reflex-mediated stiffness was not correlated to any parameters of impaired gait.CONCLUSIONS: Impaired gait function in adults with CP is associated with reduced RFD and increased passive stiffness of ankle muscles.SIGNIFICANCE: These findings suggest that reduced rapid force generation and increased passive stiffness of ankle muscles rather than increased reflex-mediated stiffness (spasticity) likely contributes to impaired gait function in adults with CP.

AB - OBJECTIVE: It is still not clarified whether spasticity contributes to impairments of gait function. Here we compared biomechanical measures of muscle weakness and stiffness of ankle muscles to impairments of gait function in adults with cerebral palsy (CP).METHODS: Twenty-four adults with CP (mean age 34.3, range 18-57years) and fifteen healthy age-matched controls were biomechanically measured for passive and reflex-mediated stiffness of the ankle plantarflexors at rest, maximal voluntary plantarflexion and dorsiflexion effort (MVCpf,df) and rate of force development (RFDpf,df). Kinematic analysis of the ankle joint during treadmill walking was obtained by 3-D motion analysis.RESULTS: Passive stiffness was significantly increased in adults with CP compared to controls. Passive stiffness and RFDdf were correlated to reduced toe lift. RFDpf provided the best correlation to push-off velocity, range of movement in the ankle joint and gait speed. Reflex-mediated stiffness was not correlated to any parameters of impaired gait.CONCLUSIONS: Impaired gait function in adults with CP is associated with reduced RFD and increased passive stiffness of ankle muscles.SIGNIFICANCE: These findings suggest that reduced rapid force generation and increased passive stiffness of ankle muscles rather than increased reflex-mediated stiffness (spasticity) likely contributes to impaired gait function in adults with CP.

U2 - 10.1016/j.clinph.2015.02.005

DO - 10.1016/j.clinph.2015.02.005

M3 - Journal article

C2 - 25757398

VL - 126

SP - 2320

EP - 2329

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 12

ER -

ID: 132433903