Functional brain imaging of tinnitus-like perception induced by aversive auditory stimuli.
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Functional brain imaging of tinnitus-like perception induced by aversive auditory stimuli. / Mirz, F; Gjedde, A; Stødkilde-Jørgensen, Hans.
In: NeuroReport, Vol. 11, No. 3, 2000, p. 633-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Functional brain imaging of tinnitus-like perception induced by aversive auditory stimuli.
AU - Mirz, F
AU - Gjedde, A
AU - Stødkilde-Jørgensen, Hans
PY - 2000
Y1 - 2000
N2 - Tinnitus is an aversive auditory percept of unknown origin. We tested the speculation that tinnitus may share neuronal processing mechanisms with aversive auditory percepts of known origin. This study revealed the functional neuroanatomy of the perception of aversive auditory stimuli. The stimuli were presented to 12 healthy volunteers so as to mimic the psychoacoustical features of tinnitus and its affective response in tinnitus sufferers. The regional cerebral blood flow distribution was measured by PET during four auditory processing conditions and one control condition. The aversive auditory stimuli activated primary and secondary auditory areas bilaterally, dorsolateral prefrontal attention areas, and structures in the limbic system which subserve emotional processing. Based on these results and findings from other functional neuroimages of tinnitus, we hypothesize that the perception of tinnitus may involve the functional linkage of these brain areas: secondary auditory cortex, dorsolateral prefrontal cortex, and limbic system.
AB - Tinnitus is an aversive auditory percept of unknown origin. We tested the speculation that tinnitus may share neuronal processing mechanisms with aversive auditory percepts of known origin. This study revealed the functional neuroanatomy of the perception of aversive auditory stimuli. The stimuli were presented to 12 healthy volunteers so as to mimic the psychoacoustical features of tinnitus and its affective response in tinnitus sufferers. The regional cerebral blood flow distribution was measured by PET during four auditory processing conditions and one control condition. The aversive auditory stimuli activated primary and secondary auditory areas bilaterally, dorsolateral prefrontal attention areas, and structures in the limbic system which subserve emotional processing. Based on these results and findings from other functional neuroimages of tinnitus, we hypothesize that the perception of tinnitus may involve the functional linkage of these brain areas: secondary auditory cortex, dorsolateral prefrontal cortex, and limbic system.
M3 - Journal article
C2 - 10718327
VL - 11
SP - 633
EP - 637
JO - NeuroReport
JF - NeuroReport
SN - 0959-4965
IS - 3
ER -
ID: 14946957