Extracellular potassium and blood flow in the post-ischemic rat brain

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Extracellular potassium and blood flow in the post-ischemic rat brain. / Hansen, Anker Jón; Gjedde, Albert; Siemkowicz, Eugeniusz.

In: Pflügers ARchiv (European Journal of Physiology), Vol. 389, No. 1, 1980, p. 1-7.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Hansen, AJ, Gjedde, A & Siemkowicz, E 1980, 'Extracellular potassium and blood flow in the post-ischemic rat brain', Pflügers ARchiv (European Journal of Physiology), vol. 389, no. 1, pp. 1-7.

APA

Hansen, A. J., Gjedde, A., & Siemkowicz, E. (1980). Extracellular potassium and blood flow in the post-ischemic rat brain. Pflügers ARchiv (European Journal of Physiology), 389(1), 1-7.

Vancouver

Hansen AJ, Gjedde A, Siemkowicz E. Extracellular potassium and blood flow in the post-ischemic rat brain. Pflügers ARchiv (European Journal of Physiology). 1980;389(1):1-7.

Author

Hansen, Anker Jón ; Gjedde, Albert ; Siemkowicz, Eugeniusz. / Extracellular potassium and blood flow in the post-ischemic rat brain. In: Pflügers ARchiv (European Journal of Physiology). 1980 ; Vol. 389, No. 1. pp. 1-7.

Bibtex

@article{354f5410b31511debc73000ea68e967b,
title = "Extracellular potassium and blood flow in the post-ischemic rat brain",
abstract = "The concentration of extracellular potassium, [K+]e, was measured in parietal cortex and basal ganglia of rats during and after ten minutes of complete cerebral ischemia. The post-ischemic normalization of [K+]e was considerably delayed in parietal cortex compared to basal ganglia, but in both regions, [K+]e reached its normal concentration within 4 min of the end of the ischemia. Also, in both regions blood flow was elevated at the time of maximal [K+]e decrease. Our findings suggest that the normalization of [K+]e and cerebrovascular resistance after ischemia are related by positive feed-back, possibly via the stimulation of Na+-K+-ATPase.",
author = "Hansen, {Anker J{\'o}n} and Albert Gjedde and Eugeniusz Siemkowicz",
year = "1980",
language = "English",
volume = "389",
pages = "1--7",
journal = "Pfl{\"u}gers Archiv - European Journal of Physiology",
issn = "0031-6768",
publisher = "Springer",
number = "1",

}

RIS

TY - JOUR

T1 - Extracellular potassium and blood flow in the post-ischemic rat brain

AU - Hansen, Anker Jón

AU - Gjedde, Albert

AU - Siemkowicz, Eugeniusz

PY - 1980

Y1 - 1980

N2 - The concentration of extracellular potassium, [K+]e, was measured in parietal cortex and basal ganglia of rats during and after ten minutes of complete cerebral ischemia. The post-ischemic normalization of [K+]e was considerably delayed in parietal cortex compared to basal ganglia, but in both regions, [K+]e reached its normal concentration within 4 min of the end of the ischemia. Also, in both regions blood flow was elevated at the time of maximal [K+]e decrease. Our findings suggest that the normalization of [K+]e and cerebrovascular resistance after ischemia are related by positive feed-back, possibly via the stimulation of Na+-K+-ATPase.

AB - The concentration of extracellular potassium, [K+]e, was measured in parietal cortex and basal ganglia of rats during and after ten minutes of complete cerebral ischemia. The post-ischemic normalization of [K+]e was considerably delayed in parietal cortex compared to basal ganglia, but in both regions, [K+]e reached its normal concentration within 4 min of the end of the ischemia. Also, in both regions blood flow was elevated at the time of maximal [K+]e decrease. Our findings suggest that the normalization of [K+]e and cerebrovascular resistance after ischemia are related by positive feed-back, possibly via the stimulation of Na+-K+-ATPase.

M3 - Journal article

C2 - 7193461

VL - 389

SP - 1

EP - 7

JO - Pflügers Archiv - European Journal of Physiology

JF - Pflügers Archiv - European Journal of Physiology

SN - 0031-6768

IS - 1

ER -

ID: 14946077