Excitatory effects of thyrotropin-releasing hormone (TRH) in hypoglossal motoneurons
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Excitatory effects of thyrotropin-releasing hormone (TRH) in hypoglossal motoneurons. / Rekling, J C.
In: Brain Research, Vol. 510, No. 1, 1990, p. 175-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Excitatory effects of thyrotropin-releasing hormone (TRH) in hypoglossal motoneurons
AU - Rekling, J C
N1 - Keywords: Action Potentials; Animals; Female; Guinea Pigs; Hypoglossal Nerve; Male; Motor Neurons; Thyrotropin-Releasing Hormone
PY - 1990
Y1 - 1990
N2 - The effect of thyrotropin-releasing hormone (TRH) was studied in 30 hypoglossal motoneurons from brainstem slices of guinea pigs. Bath application of TRH resulted in an increase of the spontaneous excitatory synaptic activity, depolarization of the neurons, increase of the input resistance and change of the duration of the falling phase of excitatory postsynaptic potentials. The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance.
AB - The effect of thyrotropin-releasing hormone (TRH) was studied in 30 hypoglossal motoneurons from brainstem slices of guinea pigs. Bath application of TRH resulted in an increase of the spontaneous excitatory synaptic activity, depolarization of the neurons, increase of the input resistance and change of the duration of the falling phase of excitatory postsynaptic potentials. The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance.
M3 - Journal article
C2 - 2108785
VL - 510
SP - 175
EP - 179
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1
ER -
ID: 9256130