Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy

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Standard

Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy. / Préel, Marie; Rackauskaite, Gija; Larsen, Mads Langager; Laursen, Bjarne; Lorentzen, Jakob; Born, Alfred Peter; Langhoff-Roos, Jens; Uldall, Peter; Høi-Hansen, Christina Engel.

In: Acta Paediatrica, Vol. 108, No. 10, 2019, p. 1850-1856.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Préel, M, Rackauskaite, G, Larsen, ML, Laursen, B, Lorentzen, J, Born, AP, Langhoff-Roos, J, Uldall, P & Høi-Hansen, CE 2019, 'Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy', Acta Paediatrica, vol. 108, no. 10, pp. 1850-1856. https://doi.org/10.1111/apa.14806

APA

Préel, M., Rackauskaite, G., Larsen, M. L., Laursen, B., Lorentzen, J., Born, A. P., Langhoff-Roos, J., Uldall, P., & Høi-Hansen, C. E. (2019). Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy. Acta Paediatrica, 108(10), 1850-1856. https://doi.org/10.1111/apa.14806

Vancouver

Préel M, Rackauskaite G, Larsen ML, Laursen B, Lorentzen J, Born AP et al. Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy. Acta Paediatrica. 2019;108(10):1850-1856. https://doi.org/10.1111/apa.14806

Author

Préel, Marie ; Rackauskaite, Gija ; Larsen, Mads Langager ; Laursen, Bjarne ; Lorentzen, Jakob ; Born, Alfred Peter ; Langhoff-Roos, Jens ; Uldall, Peter ; Høi-Hansen, Christina Engel. / Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy. In: Acta Paediatrica. 2019 ; Vol. 108, No. 10. pp. 1850-1856.

Bibtex

@article{45863fb0dbab4a588243977453f25739,
title = "Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy",
abstract = "AIM: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).METHODS: Data was extracted from the Danish nationwide CP register. Participants were born in 1999-2007 and were 5-6 years at ascertainment.RESULTS: The total number of CP cases was 1,165 of which 92 had dyskinetic and 540 bilateral spastic CP. Prevalence of dyskinetic CP was 0.16 per 1000 live-births. In participants with dyskinetic compared to bilateral spastic CP, there was more frequently an Apgar level less than five at five minutes (22.7% versus 11.2%) and neonatal seizures (43.5% versus 28.5%), but less respiratory deficiency, hyperbilirubinaemia, and sepsis. Impairment based on gross motor function classification was more severe in dyskinetic CP (level III-V 90.0% versus 66.0%). In dyskinetic CP there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%), and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spastic CP (27.7% vs. 12.8%).CONCLUSION: Cases of dyskinetic CP had overlapping clinical features with cases of bilateral spastic CP, but differed significantly in several perinatal risk factors. The children with dyskinetic CP had experienced more peri- or neonatal adverse events, and neurodevelopmental impairment was severe. This article is protected by copyright. All rights reserved.",
author = "Marie Pr{\'e}el and Gija Rackauskaite and Larsen, {Mads Langager} and Bjarne Laursen and Jakob Lorentzen and Born, {Alfred Peter} and Jens Langhoff-Roos and Peter Uldall and H{\o}i-Hansen, {Christina Engel}",
note = "This article is protected by copyright. All rights reserved.",
year = "2019",
doi = "10.1111/apa.14806",
language = "English",
volume = "108",
pages = "1850--1856",
journal = "Acta Paediatrica",
issn = "0803-5253",
publisher = "Wiley-Blackwell",
number = "10",

}

RIS

TY - JOUR

T1 - Children with dyskinetic cerebral palsy are severely affected as compared to bilateral spastic cerebral palsy

AU - Préel, Marie

AU - Rackauskaite, Gija

AU - Larsen, Mads Langager

AU - Laursen, Bjarne

AU - Lorentzen, Jakob

AU - Born, Alfred Peter

AU - Langhoff-Roos, Jens

AU - Uldall, Peter

AU - Høi-Hansen, Christina Engel

N1 - This article is protected by copyright. All rights reserved.

PY - 2019

Y1 - 2019

N2 - AIM: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).METHODS: Data was extracted from the Danish nationwide CP register. Participants were born in 1999-2007 and were 5-6 years at ascertainment.RESULTS: The total number of CP cases was 1,165 of which 92 had dyskinetic and 540 bilateral spastic CP. Prevalence of dyskinetic CP was 0.16 per 1000 live-births. In participants with dyskinetic compared to bilateral spastic CP, there was more frequently an Apgar level less than five at five minutes (22.7% versus 11.2%) and neonatal seizures (43.5% versus 28.5%), but less respiratory deficiency, hyperbilirubinaemia, and sepsis. Impairment based on gross motor function classification was more severe in dyskinetic CP (level III-V 90.0% versus 66.0%). In dyskinetic CP there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%), and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spastic CP (27.7% vs. 12.8%).CONCLUSION: Cases of dyskinetic CP had overlapping clinical features with cases of bilateral spastic CP, but differed significantly in several perinatal risk factors. The children with dyskinetic CP had experienced more peri- or neonatal adverse events, and neurodevelopmental impairment was severe. This article is protected by copyright. All rights reserved.

AB - AIM: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).METHODS: Data was extracted from the Danish nationwide CP register. Participants were born in 1999-2007 and were 5-6 years at ascertainment.RESULTS: The total number of CP cases was 1,165 of which 92 had dyskinetic and 540 bilateral spastic CP. Prevalence of dyskinetic CP was 0.16 per 1000 live-births. In participants with dyskinetic compared to bilateral spastic CP, there was more frequently an Apgar level less than five at five minutes (22.7% versus 11.2%) and neonatal seizures (43.5% versus 28.5%), but less respiratory deficiency, hyperbilirubinaemia, and sepsis. Impairment based on gross motor function classification was more severe in dyskinetic CP (level III-V 90.0% versus 66.0%). In dyskinetic CP there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%), and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spastic CP (27.7% vs. 12.8%).CONCLUSION: Cases of dyskinetic CP had overlapping clinical features with cases of bilateral spastic CP, but differed significantly in several perinatal risk factors. The children with dyskinetic CP had experienced more peri- or neonatal adverse events, and neurodevelopmental impairment was severe. This article is protected by copyright. All rights reserved.

U2 - 10.1111/apa.14806

DO - 10.1111/apa.14806

M3 - Journal article

C2 - 30933377

VL - 108

SP - 1850

EP - 1856

JO - Acta Paediatrica

JF - Acta Paediatrica

SN - 0803-5253

IS - 10

ER -

ID: 216478078