Changes in regional cerebral blood flow during the course of classic migraine attacks

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Changes in regional cerebral blood flow during the course of classic migraine attacks. / Lauritzen, Martin; Olsen, Tom Skyhøj; Lassen, Niels A.; Paulson, Olaf B.

In: Annals of Neurology, Vol. 13, No. 6, 01.01.1983, p. 633-641.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lauritzen, M, Olsen, TS, Lassen, NA & Paulson, OB 1983, 'Changes in regional cerebral blood flow during the course of classic migraine attacks', Annals of Neurology, vol. 13, no. 6, pp. 633-641. https://doi.org/10.1002/ana.410130609

APA

Lauritzen, M., Olsen, T. S., Lassen, N. A., & Paulson, O. B. (1983). Changes in regional cerebral blood flow during the course of classic migraine attacks. Annals of Neurology, 13(6), 633-641. https://doi.org/10.1002/ana.410130609

Vancouver

Lauritzen M, Olsen TS, Lassen NA, Paulson OB. Changes in regional cerebral blood flow during the course of classic migraine attacks. Annals of Neurology. 1983 Jan 1;13(6):633-641. https://doi.org/10.1002/ana.410130609

Author

Lauritzen, Martin ; Olsen, Tom Skyhøj ; Lassen, Niels A. ; Paulson, Olaf B. / Changes in regional cerebral blood flow during the course of classic migraine attacks. In: Annals of Neurology. 1983 ; Vol. 13, No. 6. pp. 633-641.

Bibtex

@article{8f2d85c172ee4e8cbb12fa476615e658,
title = "Changes in regional cerebral blood flow during the course of classic migraine attacks",
abstract = "Regional cerebral blood flow (rCBF) following carotid arteriography was studied in thirteen patients with classic migraine. Using the 133xenon intraarterial injection method, rCBF was measured in 254 areas in one hemisphere. Nine patients developed a characteristic attack following arteriography and were examined by a series of rCBF studies, spaced by intervals of 5 to 10 minutes. A wave of reduced blood flow originating in the posterior part of the brain and progressing anteriorly was observed in eight of the nine patients. The oligemia advanced at a speed of 2 mm per minute over the hemisphere, progressing anteriorly but not crossing the rolandic or sylvian sulcus. Typically, the spreading oligemia reached the primary sensorimotor area after symptoms from that area had begun and persisted there long after the focal symptoms had disappeared. The observed time course suggests that the focal symptoms are not secondary to the oligemia. We suggest that focal symptoms and blood flow changes may be secondary to spreading depression of Leao.",
author = "Martin Lauritzen and Olsen, {Tom Skyh{\o}j} and Lassen, {Niels A.} and Paulson, {Olaf B.}",
year = "1983",
month = jan,
day = "1",
doi = "10.1002/ana.410130609",
language = "English",
volume = "13",
pages = "633--641",
journal = "Annals of Neurology",
issn = "0364-5134",
publisher = "JohnWiley & Sons, Inc.",
number = "6",

}

RIS

TY - JOUR

T1 - Changes in regional cerebral blood flow during the course of classic migraine attacks

AU - Lauritzen, Martin

AU - Olsen, Tom Skyhøj

AU - Lassen, Niels A.

AU - Paulson, Olaf B.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - Regional cerebral blood flow (rCBF) following carotid arteriography was studied in thirteen patients with classic migraine. Using the 133xenon intraarterial injection method, rCBF was measured in 254 areas in one hemisphere. Nine patients developed a characteristic attack following arteriography and were examined by a series of rCBF studies, spaced by intervals of 5 to 10 minutes. A wave of reduced blood flow originating in the posterior part of the brain and progressing anteriorly was observed in eight of the nine patients. The oligemia advanced at a speed of 2 mm per minute over the hemisphere, progressing anteriorly but not crossing the rolandic or sylvian sulcus. Typically, the spreading oligemia reached the primary sensorimotor area after symptoms from that area had begun and persisted there long after the focal symptoms had disappeared. The observed time course suggests that the focal symptoms are not secondary to the oligemia. We suggest that focal symptoms and blood flow changes may be secondary to spreading depression of Leao.

AB - Regional cerebral blood flow (rCBF) following carotid arteriography was studied in thirteen patients with classic migraine. Using the 133xenon intraarterial injection method, rCBF was measured in 254 areas in one hemisphere. Nine patients developed a characteristic attack following arteriography and were examined by a series of rCBF studies, spaced by intervals of 5 to 10 minutes. A wave of reduced blood flow originating in the posterior part of the brain and progressing anteriorly was observed in eight of the nine patients. The oligemia advanced at a speed of 2 mm per minute over the hemisphere, progressing anteriorly but not crossing the rolandic or sylvian sulcus. Typically, the spreading oligemia reached the primary sensorimotor area after symptoms from that area had begun and persisted there long after the focal symptoms had disappeared. The observed time course suggests that the focal symptoms are not secondary to the oligemia. We suggest that focal symptoms and blood flow changes may be secondary to spreading depression of Leao.

UR - http://www.scopus.com/inward/record.url?scp=0020630304&partnerID=8YFLogxK

U2 - 10.1002/ana.410130609

DO - 10.1002/ana.410130609

M3 - Journal article

C2 - 6881926

AN - SCOPUS:0020630304

VL - 13

SP - 633

EP - 641

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

IS - 6

ER -

ID: 201459382