Brainstem Circuits for Locomotion

Research output: Contribution to journal › Journal article › Research › peer-review

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Brainstem Circuits for Locomotion. / Leiras, Roberto; Cregg, Jared M; Kiehn, Ole.

In: Annual Review of Neuroscience, Vol. 45, 2022, p. 63-85.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Leiras, R, Cregg, JM & Kiehn, O 2022, 'Brainstem Circuits for Locomotion', Annual Review of Neuroscience, vol. 45, pp. 63-85. https://doi.org/10.1146/annurev-neuro-082321-025137

APA

Leiras, R., Cregg, J. M., & Kiehn, O. (2022). Brainstem Circuits for Locomotion. Annual Review of Neuroscience, 45, 63-85. https://doi.org/10.1146/annurev-neuro-082321-025137

Vancouver

Leiras R, Cregg JM, Kiehn O. Brainstem Circuits for Locomotion. Annual Review of Neuroscience. 2022;45:63-85. https://doi.org/10.1146/annurev-neuro-082321-025137

Author

Leiras, Roberto ; Cregg, Jared M ; Kiehn, Ole. / Brainstem Circuits for Locomotion. In: Annual Review of Neuroscience. 2022 ; Vol. 45. pp. 63-85.

Bibtex

@article{9202532f8f884de2ac60b8a453778ec9,
title = "Brainstem Circuits for Locomotion",
abstract = "Locomotion is a universal motor behavior that is expressed as the output of many integrated brain functions. Locomotion is organized at several levels of the nervous system, with brainstem circuits acting as the gate between brain areas regulating innate, emotional, or motivational locomotion and executive spinal circuits. Here we review recent advances on brainstem circuits involved in controlling locomotion. We describe how delineated command circuits govern the start, speed, stop, and steering of locomotion. We also discuss how these pathways interface between executive circuits in the spinal cord and diverse brain areas important for context-specific selection of locomotion. A recurrent theme is the need to establish a functional connectome to and from brainstem command circuits. Finally, we point to unresolved issues concerning the integrated function of locomotor control. Expected final online publication date for the Annual Review of Neuroscience, Volume 45 is July 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.",
author = "Roberto Leiras and Cregg, {Jared M} and Ole Kiehn",
year = "2022",
doi = "10.1146/annurev-neuro-082321-025137",
language = "English",
volume = "45",
pages = "63--85",
journal = "Annual Review of Neuroscience",
issn = "0147-006X",
publisher = "Annual Reviews, inc.",

}

RIS

TY - JOUR

T1 - Brainstem Circuits for Locomotion

AU - Leiras, Roberto

AU - Cregg, Jared M

AU - Kiehn, Ole

PY - 2022

Y1 - 2022

N2 - Locomotion is a universal motor behavior that is expressed as the output of many integrated brain functions. Locomotion is organized at several levels of the nervous system, with brainstem circuits acting as the gate between brain areas regulating innate, emotional, or motivational locomotion and executive spinal circuits. Here we review recent advances on brainstem circuits involved in controlling locomotion. We describe how delineated command circuits govern the start, speed, stop, and steering of locomotion. We also discuss how these pathways interface between executive circuits in the spinal cord and diverse brain areas important for context-specific selection of locomotion. A recurrent theme is the need to establish a functional connectome to and from brainstem command circuits. Finally, we point to unresolved issues concerning the integrated function of locomotor control. Expected final online publication date for the Annual Review of Neuroscience, Volume 45 is July 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

AB - Locomotion is a universal motor behavior that is expressed as the output of many integrated brain functions. Locomotion is organized at several levels of the nervous system, with brainstem circuits acting as the gate between brain areas regulating innate, emotional, or motivational locomotion and executive spinal circuits. Here we review recent advances on brainstem circuits involved in controlling locomotion. We describe how delineated command circuits govern the start, speed, stop, and steering of locomotion. We also discuss how these pathways interface between executive circuits in the spinal cord and diverse brain areas important for context-specific selection of locomotion. A recurrent theme is the need to establish a functional connectome to and from brainstem command circuits. Finally, we point to unresolved issues concerning the integrated function of locomotor control. Expected final online publication date for the Annual Review of Neuroscience, Volume 45 is July 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

U2 - 10.1146/annurev-neuro-082321-025137

DO - 10.1146/annurev-neuro-082321-025137

M3 - Journal article

C2 - 34985919

VL - 45

SP - 63

EP - 85

JO - Annual Review of Neuroscience

JF - Annual Review of Neuroscience

SN - 0147-006X

ER -

ID: 288871762