Brain uptake of lactate, antipyrine, water and ethanol.

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Brain uptake of lactate, antipyrine, water and ethanol. / Gjedde, A; Andersson, J; Eklöf, B.

In: Acta physiologica Scandinavica, Vol. 93, No. 2, 1975, p. 145-9.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Gjedde, A, Andersson, J & Eklöf, B 1975, 'Brain uptake of lactate, antipyrine, water and ethanol.', Acta physiologica Scandinavica, vol. 93, no. 2, pp. 145-9.

APA

Gjedde, A., Andersson, J., & Eklöf, B. (1975). Brain uptake of lactate, antipyrine, water and ethanol. Acta physiologica Scandinavica, 93(2), 145-9.

Vancouver

Gjedde A, Andersson J, Eklöf B. Brain uptake of lactate, antipyrine, water and ethanol. Acta physiologica Scandinavica. 1975;93(2):145-9.

Author

Gjedde, A ; Andersson, J ; Eklöf, B. / Brain uptake of lactate, antipyrine, water and ethanol. In: Acta physiologica Scandinavica. 1975 ; Vol. 93, No. 2. pp. 145-9.

Bibtex

@article{070ed030b31511debc73000ea68e967b,
title = "Brain uptake of lactate, antipyrine, water and ethanol.",
abstract = "Brain uptake of antipyrine, water and ethanol was studied in rats under normo-, hypo- and hypercapnic conditions. Brain uptake of D- and L-lactate was studied in normal rats. The uptake was determined with the Oldendorf method, using single common carotid arterial injections of a mixture of -14C-labeled test substance and tritiated reference substance. The results demonstrate that L-lactate is taken up by the brain in significant amounts. The results also demonstrate marked differences in the uptakes of antipyrine, water and ethanol. The brain uptake of antipyrine is lower, the brain uptake of ethanol higher, than of water. The brain uptake of all 3 substances was shown not to be affected by changes in cerebral blood flow, although a decrease of brain uptake of antipyrine relative to ethanol was observed during hypo- and hypercapnia.",
author = "A Gjedde and J Andersson and B Ekl{\"o}f",
year = "1975",
language = "English",
volume = "93",
pages = "145--9",
journal = "Acta Physiologica Scandinavica",
issn = "0001-6772",
publisher = "Blackwell Science Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Brain uptake of lactate, antipyrine, water and ethanol.

AU - Gjedde, A

AU - Andersson, J

AU - Eklöf, B

PY - 1975

Y1 - 1975

N2 - Brain uptake of antipyrine, water and ethanol was studied in rats under normo-, hypo- and hypercapnic conditions. Brain uptake of D- and L-lactate was studied in normal rats. The uptake was determined with the Oldendorf method, using single common carotid arterial injections of a mixture of -14C-labeled test substance and tritiated reference substance. The results demonstrate that L-lactate is taken up by the brain in significant amounts. The results also demonstrate marked differences in the uptakes of antipyrine, water and ethanol. The brain uptake of antipyrine is lower, the brain uptake of ethanol higher, than of water. The brain uptake of all 3 substances was shown not to be affected by changes in cerebral blood flow, although a decrease of brain uptake of antipyrine relative to ethanol was observed during hypo- and hypercapnia.

AB - Brain uptake of antipyrine, water and ethanol was studied in rats under normo-, hypo- and hypercapnic conditions. Brain uptake of D- and L-lactate was studied in normal rats. The uptake was determined with the Oldendorf method, using single common carotid arterial injections of a mixture of -14C-labeled test substance and tritiated reference substance. The results demonstrate that L-lactate is taken up by the brain in significant amounts. The results also demonstrate marked differences in the uptakes of antipyrine, water and ethanol. The brain uptake of antipyrine is lower, the brain uptake of ethanol higher, than of water. The brain uptake of all 3 substances was shown not to be affected by changes in cerebral blood flow, although a decrease of brain uptake of antipyrine relative to ethanol was observed during hypo- and hypercapnia.

M3 - Journal article

C2 - 1146566

VL - 93

SP - 145

EP - 149

JO - Acta Physiologica Scandinavica

JF - Acta Physiologica Scandinavica

SN - 0001-6772

IS - 2

ER -

ID: 14943566