Autoradiographic determination of regional brain glucose content.

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Standard

Autoradiographic determination of regional brain glucose content. / Gjedde, A; Diemer, N H.

In: Journal of Cerebral Blood Flow and Metabolism, Vol. 3, No. 3, 1983, p. 303-10.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gjedde, A & Diemer, NH 1983, 'Autoradiographic determination of regional brain glucose content.', Journal of Cerebral Blood Flow and Metabolism, vol. 3, no. 3, pp. 303-10.

APA

Gjedde, A., & Diemer, N. H. (1983). Autoradiographic determination of regional brain glucose content. Journal of Cerebral Blood Flow and Metabolism, 3(3), 303-10.

Vancouver

Gjedde A, Diemer NH. Autoradiographic determination of regional brain glucose content. Journal of Cerebral Blood Flow and Metabolism. 1983;3(3):303-10.

Author

Gjedde, A ; Diemer, N H. / Autoradiographic determination of regional brain glucose content. In: Journal of Cerebral Blood Flow and Metabolism. 1983 ; Vol. 3, No. 3. pp. 303-10.

Bibtex

@article{42b225b0b31511debc73000ea68e967b,
title = "Autoradiographic determination of regional brain glucose content.",
abstract = "Brain glucose content is an important experimental variable that affects the value of the {"}lumped constant{"} of the 2-deoxyglucose method. The apparent volume of distribution in brain of the nonmetabolizable glucose analog, 3-O-methylglucose, depends only on the glucose content. From the kinetic constants of glucose transport and the apparent volume of distribution, we used autoradiography to calculate the regional glucose content of the normal rat brain. The regional glucose content varied only insignificantly in gray matter regions; the average glucose content of all rat brain slices examined was 4 mumol g-1, with an average plasma glucose concentration of 8.6 mM. Regional values varied between 3.4 and 4.6 mumol g-1. Thus, there is no reason to believe that the regional values of the lumped constant vary significantly in normal rat brains.",
author = "A Gjedde and Diemer, {N H}",
year = "1983",
language = "English",
volume = "3",
pages = "303--10",
journal = "Journal of Cerebral Blood Flow and Metabolism",
issn = "0271-678X",
publisher = "SAGE Publications",
number = "3",

}

RIS

TY - JOUR

T1 - Autoradiographic determination of regional brain glucose content.

AU - Gjedde, A

AU - Diemer, N H

PY - 1983

Y1 - 1983

N2 - Brain glucose content is an important experimental variable that affects the value of the "lumped constant" of the 2-deoxyglucose method. The apparent volume of distribution in brain of the nonmetabolizable glucose analog, 3-O-methylglucose, depends only on the glucose content. From the kinetic constants of glucose transport and the apparent volume of distribution, we used autoradiography to calculate the regional glucose content of the normal rat brain. The regional glucose content varied only insignificantly in gray matter regions; the average glucose content of all rat brain slices examined was 4 mumol g-1, with an average plasma glucose concentration of 8.6 mM. Regional values varied between 3.4 and 4.6 mumol g-1. Thus, there is no reason to believe that the regional values of the lumped constant vary significantly in normal rat brains.

AB - Brain glucose content is an important experimental variable that affects the value of the "lumped constant" of the 2-deoxyglucose method. The apparent volume of distribution in brain of the nonmetabolizable glucose analog, 3-O-methylglucose, depends only on the glucose content. From the kinetic constants of glucose transport and the apparent volume of distribution, we used autoradiography to calculate the regional glucose content of the normal rat brain. The regional glucose content varied only insignificantly in gray matter regions; the average glucose content of all rat brain slices examined was 4 mumol g-1, with an average plasma glucose concentration of 8.6 mM. Regional values varied between 3.4 and 4.6 mumol g-1. Thus, there is no reason to believe that the regional values of the lumped constant vary significantly in normal rat brains.

M3 - Journal article

C2 - 6874739

VL - 3

SP - 303

EP - 310

JO - Journal of Cerebral Blood Flow and Metabolism

JF - Journal of Cerebral Blood Flow and Metabolism

SN - 0271-678X

IS - 3

ER -

ID: 14946808