Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig. / Waaben, J; Sørensen, H R; Andersen, U L; Gefke, K; Lund, J; Aggestrup, S; Husum, B; Laursen, H; Gjedde, A.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 107, No. 4, 1994, p. 1030-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Waaben, J, Sørensen, HR, Andersen, UL, Gefke, K, Lund, J, Aggestrup, S, Husum, B, Laursen, H & Gjedde, A 1994, 'Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig.', Journal of Thoracic and Cardiovascular Surgery, vol. 107, no. 4, pp. 1030-5.

APA

Waaben, J., Sørensen, H. R., Andersen, U. L., Gefke, K., Lund, J., Aggestrup, S., Husum, B., Laursen, H., & Gjedde, A. (1994). Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig. Journal of Thoracic and Cardiovascular Surgery, 107(4), 1030-5.

Vancouver

Waaben J, Sørensen HR, Andersen UL, Gefke K, Lund J, Aggestrup S et al. Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig. Journal of Thoracic and Cardiovascular Surgery. 1994;107(4):1030-5.

Author

Waaben, J ; Sørensen, H R ; Andersen, U L ; Gefke, K ; Lund, J ; Aggestrup, S ; Husum, B ; Laursen, H ; Gjedde, A. / Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig. In: Journal of Thoracic and Cardiovascular Surgery. 1994 ; Vol. 107, No. 4. pp. 1030-5.

Bibtex

@article{38ee25b0b31511debc73000ea68e967b,
title = "Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig.",
abstract = "Microemboli in the brain may inhibit brain function during cardiopulmonary bypass, and in a previous study in pigs of normothermic nonpulsatile bypass we reported a significant decrease in cerebral glucose consumption secondary to interruption of the capillary flow, possibly caused by microemboli. In the present study we measured the regional cerebral glucose consumption and the regional capillary diffusion capacity (that is, the number of perfused capillaries) in 10 different brain regions in two separate groups of animals with and without an arterial filter during normothermic cardiopulmonary bypass. Inclusion of a 40 micron arterial filter in the bypass circuit increased the regional brain glucose consumption 27% (median; range -12% to 145%) and regional capillary diffusion capacity increased 123% (median; range 36% to 829%). No change in brain histologic features, the cerebrovascular permeability to serum proteins, or cerebral water content was observed. The arterial filter probably protects the cerebral microcirculation and prevents the decrease in cerebral glucose consumption otherwise seen during bypass.",
author = "J Waaben and S{\o}rensen, {H R} and Andersen, {U L} and K Gefke and J Lund and S Aggestrup and B Husum and H Laursen and A Gjedde",
year = "1994",
language = "English",
volume = "107",
pages = "1030--5",
journal = "Journal of Thoracic and Cardiovascular Surgery",
issn = "0022-5223",
publisher = "Mosby Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Arterial line filtration protects brain microcirculation during cardiopulmonary bypass in the pig.

AU - Waaben, J

AU - Sørensen, H R

AU - Andersen, U L

AU - Gefke, K

AU - Lund, J

AU - Aggestrup, S

AU - Husum, B

AU - Laursen, H

AU - Gjedde, A

PY - 1994

Y1 - 1994

N2 - Microemboli in the brain may inhibit brain function during cardiopulmonary bypass, and in a previous study in pigs of normothermic nonpulsatile bypass we reported a significant decrease in cerebral glucose consumption secondary to interruption of the capillary flow, possibly caused by microemboli. In the present study we measured the regional cerebral glucose consumption and the regional capillary diffusion capacity (that is, the number of perfused capillaries) in 10 different brain regions in two separate groups of animals with and without an arterial filter during normothermic cardiopulmonary bypass. Inclusion of a 40 micron arterial filter in the bypass circuit increased the regional brain glucose consumption 27% (median; range -12% to 145%) and regional capillary diffusion capacity increased 123% (median; range 36% to 829%). No change in brain histologic features, the cerebrovascular permeability to serum proteins, or cerebral water content was observed. The arterial filter probably protects the cerebral microcirculation and prevents the decrease in cerebral glucose consumption otherwise seen during bypass.

AB - Microemboli in the brain may inhibit brain function during cardiopulmonary bypass, and in a previous study in pigs of normothermic nonpulsatile bypass we reported a significant decrease in cerebral glucose consumption secondary to interruption of the capillary flow, possibly caused by microemboli. In the present study we measured the regional cerebral glucose consumption and the regional capillary diffusion capacity (that is, the number of perfused capillaries) in 10 different brain regions in two separate groups of animals with and without an arterial filter during normothermic cardiopulmonary bypass. Inclusion of a 40 micron arterial filter in the bypass circuit increased the regional brain glucose consumption 27% (median; range -12% to 145%) and regional capillary diffusion capacity increased 123% (median; range 36% to 829%). No change in brain histologic features, the cerebrovascular permeability to serum proteins, or cerebral water content was observed. The arterial filter probably protects the cerebral microcirculation and prevents the decrease in cerebral glucose consumption otherwise seen during bypass.

M3 - Journal article

C2 - 8159023

VL - 107

SP - 1030

EP - 1035

JO - Journal of Thoracic and Cardiovascular Surgery

JF - Journal of Thoracic and Cardiovascular Surgery

SN - 0022-5223

IS - 4

ER -

ID: 14946287