Arcuate nucleus, median eminence, and hypophysial pars tuberalis

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Arcuate nucleus, median eminence, and hypophysial pars tuberalis. / Korf, Horst Werner; Møller, Morten.

Handbook of Clinical Neurology. ed. / Dick F. Swaab; Felix Kreier; Paul J. Lucassen; Ahmad Salehi; Ruud M. Buijs. 1. ed. Elsevier, 2021. p. 227-251 (Handbook of Clinical Neurology, Vol. 180).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Korf, HW & Møller, M 2021, Arcuate nucleus, median eminence, and hypophysial pars tuberalis. in DFS, FK, PJL, AS & RMB (eds), Handbook of Clinical Neurology. 1 edn, Elsevier, Handbook of Clinical Neurology, vol. 180, pp. 227-251. https://doi.org/10.1016/B978-0-12-820107-7.00015-X

APA

Korf, H. W., & Møller, M. (2021). Arcuate nucleus, median eminence, and hypophysial pars tuberalis. In D. F. S., F. K., P. J. L., A. S., & R. M. B. (Eds.), Handbook of Clinical Neurology (1 ed., pp. 227-251). Elsevier. Handbook of Clinical Neurology Vol. 180 https://doi.org/10.1016/B978-0-12-820107-7.00015-X

Vancouver

Korf HW, Møller M. Arcuate nucleus, median eminence, and hypophysial pars tuberalis. In DFS, FK, PJL, AS, RMB, editors, Handbook of Clinical Neurology. 1 ed. Elsevier. 2021. p. 227-251. (Handbook of Clinical Neurology, Vol. 180). https://doi.org/10.1016/B978-0-12-820107-7.00015-X

Author

Korf, Horst Werner ; Møller, Morten. / Arcuate nucleus, median eminence, and hypophysial pars tuberalis. Handbook of Clinical Neurology. editor / Dick F. Swaab ; Felix Kreier ; Paul J. Lucassen ; Ahmad Salehi ; Ruud M. Buijs. 1. ed. Elsevier, 2021. pp. 227-251 (Handbook of Clinical Neurology, Vol. 180).

Bibtex

@inbook{e4c98311307242d7bc188ea6e57f90d0,
title = "Arcuate nucleus, median eminence, and hypophysial pars tuberalis",
abstract = "The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME. The ARC comprises several distinct types of neurons controlling prolactin release, food intake, and metabolism as well as reproduction and onset of puberty. The ME lacks a blood–brain barrier and provides an entry for peripheral signals (nutrients, leptin, ghrelin). ARC neurons are adjacent to the wall of the third ventricle. This facilitates the exchange of signals from and to the cerebrospinal fluid. The ventricular wall is composed of tanycytes that serve different functions. Axons of ARC neurons contribute to the tuberoinfundibular tract terminating in the ME on the hypophysial portal vessels (HPV) and establish one of the neurohumoral links between the hypothalamus and the pituitary. ARC neurons are reciprocally connected with several other hypothalamic nuclei, the brainstem, and reward pathways. The hypophysial pars tuberalis (PT) is attached to the ME and the HPV. The PT, an important interface of the neuroendocrine system, is mandatory for the control of seasonal functions. This contribution provides an update of our knowledge about the ARC-ME complex and the PT which, inter alia, is needed to understand the pathophysiology of metabolic diseases and reproduction.",
keywords = "Agouti-related peptide, Dopamine, Feeding, Gonadotropin-releasing hormone, Kisspeptin, Metabolism, Neuropeptide Y, Proopiomelanocortin, Tanycytes, Thyroid-stimulating hormone",
author = "Korf, {Horst Werner} and Morten M{\o}ller",
note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",
year = "2021",
doi = "10.1016/B978-0-12-820107-7.00015-X",
language = "English",
isbn = "978-0-12-820107-7",
series = "Handbook of Clinical Neurology",
publisher = "Elsevier",
pages = "227--251",
editor = "{Dick F. Swaab} and {Felix Kreier} and {Paul J. Lucassen} and {Ahmad Salehi} and {Ruud M. Buijs}",
booktitle = "Handbook of Clinical Neurology",
address = "Netherlands",
edition = "1",

}

RIS

TY - CHAP

T1 - Arcuate nucleus, median eminence, and hypophysial pars tuberalis

AU - Korf, Horst Werner

AU - Møller, Morten

N1 - Publisher Copyright: © 2021 Elsevier B.V.

PY - 2021

Y1 - 2021

N2 - The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME. The ARC comprises several distinct types of neurons controlling prolactin release, food intake, and metabolism as well as reproduction and onset of puberty. The ME lacks a blood–brain barrier and provides an entry for peripheral signals (nutrients, leptin, ghrelin). ARC neurons are adjacent to the wall of the third ventricle. This facilitates the exchange of signals from and to the cerebrospinal fluid. The ventricular wall is composed of tanycytes that serve different functions. Axons of ARC neurons contribute to the tuberoinfundibular tract terminating in the ME on the hypophysial portal vessels (HPV) and establish one of the neurohumoral links between the hypothalamus and the pituitary. ARC neurons are reciprocally connected with several other hypothalamic nuclei, the brainstem, and reward pathways. The hypophysial pars tuberalis (PT) is attached to the ME and the HPV. The PT, an important interface of the neuroendocrine system, is mandatory for the control of seasonal functions. This contribution provides an update of our knowledge about the ARC-ME complex and the PT which, inter alia, is needed to understand the pathophysiology of metabolic diseases and reproduction.

AB - The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME. The ARC comprises several distinct types of neurons controlling prolactin release, food intake, and metabolism as well as reproduction and onset of puberty. The ME lacks a blood–brain barrier and provides an entry for peripheral signals (nutrients, leptin, ghrelin). ARC neurons are adjacent to the wall of the third ventricle. This facilitates the exchange of signals from and to the cerebrospinal fluid. The ventricular wall is composed of tanycytes that serve different functions. Axons of ARC neurons contribute to the tuberoinfundibular tract terminating in the ME on the hypophysial portal vessels (HPV) and establish one of the neurohumoral links between the hypothalamus and the pituitary. ARC neurons are reciprocally connected with several other hypothalamic nuclei, the brainstem, and reward pathways. The hypophysial pars tuberalis (PT) is attached to the ME and the HPV. The PT, an important interface of the neuroendocrine system, is mandatory for the control of seasonal functions. This contribution provides an update of our knowledge about the ARC-ME complex and the PT which, inter alia, is needed to understand the pathophysiology of metabolic diseases and reproduction.

KW - Agouti-related peptide

KW - Dopamine

KW - Feeding

KW - Gonadotropin-releasing hormone

KW - Kisspeptin

KW - Metabolism

KW - Neuropeptide Y

KW - Proopiomelanocortin

KW - Tanycytes

KW - Thyroid-stimulating hormone

U2 - 10.1016/B978-0-12-820107-7.00015-X

DO - 10.1016/B978-0-12-820107-7.00015-X

M3 - Book chapter

C2 - 34225932

AN - SCOPUS:85109432635

SN - 978-0-12-820107-7

T3 - Handbook of Clinical Neurology

SP - 227

EP - 251

BT - Handbook of Clinical Neurology

A2 - null, Dick F. Swaab

A2 - null, Felix Kreier

A2 - null, Paul J. Lucassen

A2 - null, Ahmad Salehi

A2 - null, Ruud M. Buijs

PB - Elsevier

ER -

ID: 276334177