An automated online positioning system and simulation environment for multi-electrodes in extracellular recordings
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An automated online positioning system and simulation environment for multi-electrodes in extracellular recordings. / Franke, Felix; Natora, Michal; Meier, Philipp; Hagen, Espen; Pettersen, Klas H; Lindén, Henrik; Einevoll, Gaute T; Obermayer, Klaus.
In: I E E E Engineering in Medicine and Biology Society. Conference Proceedings, Vol. 2010, 2010, p. 593-7.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - An automated online positioning system and simulation environment for multi-electrodes in extracellular recordings
AU - Franke, Felix
AU - Natora, Michal
AU - Meier, Philipp
AU - Hagen, Espen
AU - Pettersen, Klas H
AU - Lindén, Henrik
AU - Einevoll, Gaute T
AU - Obermayer, Klaus
PY - 2010
Y1 - 2010
N2 - Extracellular recordings are a key tool to record the activity of neurons in vivo. Especially in the case of experiments with behaving animals, however, the tedious procedure of electrode placement can take a considerable amount of expensive and restricted experimental time. Furthermore, due to tissue drifts and other sources of variability in the recording setup, the position of the electrodes with respect to the recorded neurons can change causing low recording quality. The contributions of this work are threefold. We introduce a quality measure for the recording position of the electrode which should be maximized during recordings and is especially suitable for the use of multi-electrodes. An automated positioning system based on this quality measure is proposed. The system is able to find favorable recording positions and adapts the electrode position smoothly to changes of the neuron positions. Finally, we evaluate the system using a new simulator for extracellular recordings based on realistically reconstructed 3D neurons.
AB - Extracellular recordings are a key tool to record the activity of neurons in vivo. Especially in the case of experiments with behaving animals, however, the tedious procedure of electrode placement can take a considerable amount of expensive and restricted experimental time. Furthermore, due to tissue drifts and other sources of variability in the recording setup, the position of the electrodes with respect to the recorded neurons can change causing low recording quality. The contributions of this work are threefold. We introduce a quality measure for the recording position of the electrode which should be maximized during recordings and is especially suitable for the use of multi-electrodes. An automated positioning system based on this quality measure is proposed. The system is able to find favorable recording positions and adapts the electrode position smoothly to changes of the neuron positions. Finally, we evaluate the system using a new simulator for extracellular recordings based on realistically reconstructed 3D neurons.
KW - Action Potentials
KW - Animals
KW - Cats
KW - Computer Simulation
KW - Electrodes, Implanted
KW - Electrodiagnosis
KW - Models, Neurological
KW - Online Systems
KW - Prosthesis Implantation
KW - Pyramidal Cells
KW - Robotics
U2 - 10.1109/IEMBS.2010.5626631
DO - 10.1109/IEMBS.2010.5626631
M3 - Journal article
C2 - 21096103
VL - 2010
SP - 593
EP - 597
JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SN - 0589-1019
ER -
ID: 50204821