Søren Gøgsig Faarup Rasmussen

Søren Gøgsig Faarup Rasmussen

Associate Professor

ORCID: 0000-0002-1853-1841

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  1. Published

    A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, K., Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In: Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A general protocol for the generation of Nanobodies for structural biology

    Pardon, E., Laeremans, T., Triest, S., Rasmussen, Søren Gøgsig Faarup, Wohlkönig, A., Ruf, A., Muyldermans, S., Hol, W. G. J., Kobilka, B. K. & Steyaert, J., Mar 2014, In: Nature Protocols (Print). 9, 3, p. 674-93 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A monoclonal antibody for G protein-coupled receptor crystallography

    Day, P. W., Rasmussen, Søren Gøgsig Faarup, Parnot, C., Fung, J. J., Masood, A., Kobilka, T. S., Yao, X., Choi, H., Weis, W. I., Rohrer, D. K. & Kobilka, B. K., Nov 2007, In: Nature Methods. 4, 11, p. 927-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

    Whorton, M. R., Bokoch, M. P., Rasmussen, Søren Gøgsig Faarup, Huang, B., Zare, R. N., Kobilka, B. & Sunahara, R. K., 1 May 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 18, p. 7682-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6

    Ballesteros, J. A., Jensen, A. D., Liapakis, G., Rasmussen, Søren Gøgsig Faarup, Shi, L. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (31), p. 29171-29177

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

    Jensen, A. D., Guarnieri, F., Rasmussen, Søren Gøgsig Faarup, Asmar, F., Ballesteros, J. A. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (12), p. 9279-9290

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

    DeVree, B. T., Mahoney, J. P., Vélez-Ruiz, G. A., Rasmussen, Søren Gøgsig Faarup, Kuszak, A. J., Edwald, E., Fung, J., Manglik, A., Masureel, M., Du, Y., Matt, R. A., Pardon, E., Steyaert, J., Kobilka, B. K. & Sunahara, R. K., 2016, In: Nature. 535, p. 182-6

    Research output: Contribution to journal › Letter › Research › peer-review

  8. Published

    Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites

    Plenge, P., Gether, Ulrik & Rasmussen, Søren Gøgsig Faarup, 2007, In: European Journal of Pharmacology. 567, 1-2, p. 1-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Assembly of a GPCR-G Protein Complex

    Du, Y., Duc, N. M., Rasmussen, Søren Gøgsig Faarup, Hilger, D., Kubiak, X., Wang, L., Bohon, J., Kim, H. R., Wegrecki, M., Asuru, A., Jeong, K. M., Lee, J., Chance, M. R., Lodowski, D. T., Kobilka, B. K. & Chung, K. Y., 2019, In: Cell. 177, 5, p. 1232-1242

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

    Rasmussen, Søren Gøgsig Faarup, Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, Ulrik, 2001, In: Journal of Biological Chemistry. 276 (7), p. 4717-4723

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor

    Zocher, M., Zhang, C., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. K. & Müller, D. J., 11 Dec 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 50, p. E3463–E3472

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Conformational biosensors reveal GPCR signalling from endosomes

    Irannejad, R., Tomshine, J. C., Tomshine, J. R., Chevalier, M., Mahoney, J. P., Steyaert, J., Rasmussen, Søren Gøgsig Faarup, Sunahara, R. K., El-Samad, H., Huang, B. & von Zastrow, M., 28 Mar 2013, In: Nature. 495, 7442, p. 534-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

    Chung, K. Y., Rasmussen, Søren Gøgsig Faarup, Liu, T., Li, S., DeVree, B. T., Chae, P. S., Calinski, D., Kobilka, B. K., Woods, V. L. & Sunahara, R. K., 29 Sep 2011, In: Nature. 477, 7366, p. 611-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Correction to "tandem facial amphiphiles for membrane protein stabilization"

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In: Journal of the American Chemical Society. 135, 34, p. 12922 1 p.

    Research output: Contribution to journal › Journal article › Research

  16. Published

    Crystal Structures of the ß2-Adrenergic Receptor

    Weis, W. I., Rosenbaum, D., Rasmussen, Søren Gøgsig Faarup & et. al, E. A., 2009, From Molecules to Medicines, Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism. Springer, p. 217-230 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  17. Published

    Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

    Rasmussen, Søren Gøgsig Faarup, Choi, H., Rosenbaum, D. M., Kobilka, T. S., Thian, F. S., Edwards, P. C., Burghammer, M., Ratnala, V. R. P., Sanishvili, R., Fischetti, R. F., Schertler, G. F. X., Weis, W. I. & Kobilka, B. K., 15 Nov 2007, In: Nature. 450, 7168, p. 383-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Crystal structure of the β2 adrenergic receptor-Gs protein complex

    Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, Jesper M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K., 29 Sep 2011, In: Nature. 477, 7366, p. 549-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Developing an Assay to Probe Activtion and Conformational Dynamics of beta 2-Adrenergic Receptor on Single Molecule Level

    Veshaguri, S., Tutkus, M., Lundgaard, C. V., Tonnesen, A., Mathiasen, Signe, Jorgensen, S. K., Iversen, L., Hatzakis, Nikos, Rasmussen, Søren Gøgsig Faarup & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Functional studies of isolated GPCR-G protein complexes in the membrane bilayer of lipoprotein particles

    Kuszak, A. J., Yao, X. J., Rasmussen, Søren Gøgsig Faarup, Kobilka, B. & Sunahara, R. K., Dec 2010, G Protein-Coupled Receptors . Cambridge University Press, p. 32-52

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  21. Published

    Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor

    Boyhus, L. E., Danielsen, Mia, Bengtson, N. S., Kunze, M. B. A., Kubiak, X., Sminia, T. J., Løper, J. H., Tran, P. T., Lindorff-Larsen, Kresten, Rasmussen, Søren Gøgsig Faarup, Mathiesen, Jesper M. & Pedersen, D. S., 2018, In: RSC Advances. 8, 4, p. 2219-2228 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

    Rosenbaum, D. M., Cherezov, V., Hanson, M. A., Rasmussen, Søren Gøgsig Faarup, Thian, F. S., Kobilka, T. S., Choi, H., Yao, X., Weis, W. I., Stevens, R. C. & Kobilka, B. K., 23 Nov 2007, In: Science (New York, N.Y.). 318, 5854, p. 1266-73 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

    Chae, P. S., Rana, R. R., Gotfryd, K., Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In: Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

    Cherezov, V., Rosenbaum, D. M., Hanson, M. A., Rasmussen, Søren Gøgsig Faarup, Thian, F. S., Kobilka, T. S., Choi, H., Kuhn, P., Weis, W. I., Kobilka, B. K. & Stevens, R. C., 23 Nov 2007, In: Science (New York, N.Y.). 318, 5854, p. 1258-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum

    Selao, T. T., Branca, R., Chae, P. S., Lehtiö, J., Gellman, S. H., Rasmussen, Søren Gøgsig Faarup, Nordlund, S. & Norén, A., 3 Jun 2011, In: Journal of Proteome Research. 10, 6, p. 2703-14 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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