Claus Juul Løland

Claus Juul Løland

Professor


  1. 2020
  2. Published

    New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability

    Ehsan, M., Katsube, S., Cecchetti, C., Du, Y., Mortensen, Jonas Sigurd, Wang, H., Nygaard, Andreas, Ghani, L., Loland, Claus Juul, Kobilka, B. K., Byrne, B., Guan, L. & Chae, P. S., 2020, In: ACS chemical biology. 15, 6, p. 1697-1707 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization

    Bae, H. E., Cecchetti, C., Du, Y., Katsube, S., Mortensen, Jonas Sigurd, Huang, W., Rehan, S., Lee, H. J., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., 2020, In: Acta Biomaterialia. 112, p. 250-261 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS

    Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, Solveig Gaarde, Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Short-Range Distance Measurement by Transition Metal Ion FRET

    Mortensen, Jonas Sigurd & Loland, Claus Juul, 2020, Biophysics of membrane proteins. Humana Press, p. 299-311 13 p. (Methods in Molecular Biology, Vol. 2168).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability

    Slack, R. D., Ku, T. C., Cao, J., Giancola, J. L. B., Bonifazi, A., Loland, Claus Juul, Gadiano, A., Lam, J., Rais, R., Slusher, B. S., Coggiano, M., Tanda, G. & Newman, A. H., 2020, In: Journal of Medicinal Chemistry. 63, 5, p. 2343-2357 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

    Plenge, P., Abramyan, A. M., Sørensen, G., Mork, A., Weikop, Pia, Gether, Ulrik, Bang-Andersen, B., Shi, L. & Loland, Claus Juul, 2020, In: Nature Communications. 11, 1, 12 p., 1491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

    Gotfryd, K., Boesen, T., Mortensen, Jonas Sigurd, Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In: Nature Communications. 11, 1, 14 p., 1005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2019
  10. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    1,3,5-Triazine-Cored Maltoside Amphiphiles for Membrane Protein Extraction and Stabilization

    Ghani, L., Munk, C. F., Zhang, X., Katsube, S., Du, Y., Cecchetti, C., Huang, W., Bae, H. E., Saouros, S., Ehsan, M., Guan, L., Liu, X., Loland, Claus Juul, Kobilka, B. K., Byrne, B. & Chae, P. S., 2019, In: Journal of the American Chemical Society. 141, 50, p. 19677-19687 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability

    Bae, H. E., Du, Y., Hariharan, P., Mortensen, Jonas Sigurd, Kumar, K. K., Ha, B., Das, M., Lee, H. S., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2019, In: Chemical Science. 10, 4, p. 1107-1116

    Research output: Contribution to journalJournal articleResearchpeer-review

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