Claus Juul Løland

Claus Juul Løland

Professor

ORCID: 0000-0002-1773-1446

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  1. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In: European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS

    Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Probing the impact of temperature and substrates on the conformational dynamics of the Neurotransmitter:Sodium symporter LeuT

    Calugareanu, D., Möller, I. R., Schmidt, S. G., Loland, Claus Juul & Rand, Kasper Dyrberg, 2022, In: Journal of Molecular Biology. 434, 2, 15 p., 167356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse

    Loland, Claus Juul, Mereu, M., Okunola, O. M., Cao, J., Prisinzano, T. E., Mazier, S., Kopajtic, T., Shi, L., Katz, J. L., Tanda, G. & Newman, A. H., Sep 2012, In: Biological Psychiatry. 72, 5, p. 405-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization

    Yoon, S., Bae, H. E., Hariharan, P., Nygaard, Andreas, Lan, B., Woubshete, M., Sadaf, A., Liu, X., Loland, Claus Juul, Byrne, B., Guan, L. & Chae, P. S., 2024, In: Bioconjugate Chemistry. 35, 2, p. 223–231 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Rationally Engineered Tandem Facial Amphiphiles for Improved Membrane Protein Stabilization Efficacy

    Das, M., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Lee, H. S., Byrne, B., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2018, In: ChemBioChem. 19, 20, p. 2225-2232 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Realizing integration in structural biology: The 2022 ISBUC Annual Meeting

    Kragelund, Birthe Brandt, Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen Laurence, Gajhede, Michael, Christensen, Caspar Elo & Holt, Lucy, 2023, In: Structure. 31, 7, p. 747-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In: Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In: Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Resorcinarene-Based Facial Glycosides: Implication of Detergent Flexibility on Membrane-Protein Stability

    Hussain, H., Du, Y., Tikhonova, E., Mortensen, Jonas Sigurd, Ribeiro, O., Santillan, C., Das, M., Ehsan, M., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., 2017, In: Chemistry - A European Journal. 23, 28, p. 6724-6729 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

    Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In: Pharmacological Reviews. 63, 3, p. 585-640 56 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Self-Assembly Behavior and Application of Terphenyl-Cored Trimaltosides for Membrane-Protein Studies: Impact of Detergent Hydrophobic Group Geometry on Protein Stability

    Ehsan, M., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Qu, Q., Ghani, L., Das, M., Grethen, A., Byrne, B., Skiniotis, G., Keller, S., Loland, Claus Juul, Guan, L., Kobilka, B. K. & Chae, P. S., 2019, In: Chemistry: A European Journal. 25, 49, p. 11545-11554

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Self-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study

    Ehsan, M., Kumar, A., Mortensen, Jonas Sigurd, Du, Y., Hariharan, P., Kumar, K. K., Ha, B., Byrne, B., Guan, L., Kobilka, B. K., Loland, Claus Juul & Chae, P. S., 2019, In: Chemistry - An Asian Journal. 14, 11, p. 1926-1931 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Series of (([1,1′-Biphenyl]-2-yl)methyl)sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity

    Ku, T. C., Cao, J., Won, S. J., Guo, J., Camacho-Hernandez, G. A., Okorom, A. V., Salomon, Kristine Walløe, Lee, K. H., Loland, Claus Juul, Duff, H. J., Shi, L. & Newman, A. H., 2024, In: ACS Pharmacology and Translational Science. 7, 2, p. 515-532 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Short-Range Distance Measurement by Transition Metal Ion FRET

    Mortensen, Jonas Sigurd & Loland, Claus Juul, 2020, Biophysics of membrane proteins. Humana Press, p. 299-311 13 p. (Methods in Molecular Biology, Vol. 2168).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  18. Published

    Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter

    Plenge, P., Shi, L., Beuming, T., Te, J., Newman, A. H., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 16 Nov 2012, In: The Journal of Biological Chemistry. 287, 47, p. 39316-26 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Steroid-based amphiphiles for membrane protein study: The importance of alkyl spacers for protein stability

    Ehsan, M., Das, M., Stern, V., Du, Y., Mortensen, Jonas Sigurd, Hariharan, P., Byrne, B., Loland, Claus Juul, Kobilka, B. K., Guan, L. & Chae, P. S., 2018, In: ChemBioChem. 19, 13, p. 1433-1443 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J. A., Weinstein, H. & Gether, Ulrik, 2001, In: Biochemistry. 39 (51), p. 15836-15846

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J., Weinstein, H. & Gether, Ulrik, 26 Dec 2000, In: Biochemistry. 39, 51, p. 15836-15846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders

    Zou, M. F., Cao, J., Abramyan, A. M., Kopajtic, T., Zanettini, C., Guthrie, D. A., Rais, R., Slusher, B. S., Shi, L., Loland, Claus Juul & Newman, A. H., Dec 2017, In: Journal of Medicinal Chemistry. 60, 24, p. 10172-10187 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability

    Slack, R. D., Ku, T. C., Cao, J., Giancola, J. L. B., Bonifazi, A., Loland, Claus Juul, Gadiano, A., Lam, J., Rais, R., Slusher, B. S., Coggiano, M., Tanda, G. & Newman, A. H., 2020, In: Journal of Medicinal Chemistry. 63, 5, p. 2343-2357 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Substrate-Induced Conformational Dynamics of the Dopamine Transporter

    Nielsen, A. K., Moller, I. R., Rasmussen, Søren Gøgsig Faarup, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Biophysical Society. Annual Meeting. Abstracts. 116, 3, p. 346A 1 p., 1714-Pos.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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