Claus Juul Løland
Professor
Neuropharm and Genetics
Blegdamsvej 3
2200 København N.
- 2020
- Published
Allosteric Modulation of Neurotransmitter Transporters as a Therapeutic Strategy
Niello, M., Gradisch, R., Loland, Claus Juul, Stockner, T. & Sitte, H. H., 2020, In: Trends in Pharmacological Sciences. 41, 7, p. 446-463 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Diastereomeric Cyclopentane-Based Maltosides (CPMs) as Tools for Membrane Protein Study
Das, M., Mahler, F., Hariharan, P., Wang, H., Du, Y., Mortensen, Jonas Sigurd, Patallo, E. P., Ghani, L., Glück, D., Lee, H. J., Byrne, B., Loland, Claus Juul, Guan, L., Kobilka, B. K., Keller, S. & Chae, P. S., 2020, In: Journal of the American Chemical Society. 142, 51, p. 21382–21392 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Malonate-Derived Tetraglucoside Detergents for Membrane Protein Stability
Ehsan, M., Katsube, S., Cecchetti, C., Du, Y., Mortensen, Jonas Sigurd, Wang, H., Nygaard, Andreas, Ghani, L., Loland, Claus Juul, Kobilka, B. K., Byrne, B., Guan, L. & Chae, P. S., 2020, In: ACS chemical biology. 15, 6, p. 1697-1707 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization
Bae, H. E., Cecchetti, C., Du, Y., Katsube, S., Mortensen, Jonas Sigurd, Huang, W., Rehan, S., Lee, H. J., Loland, Claus Juul, Guan, L., Kobilka, B. K., Byrne, B. & Chae, P. S., 2020, In: Acta Biomaterialia. 112, p. 250-261 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the conformational impact of detergents on the integral membrane protein LeuT by global HDX-MS
Möller, I. R., Merkle, P. S., Calugareanu, D., Comamala, G., Schmidt, Solveig Gaarde, Loland, Claus Juul & Rand, Kasper Dyrberg, 2020, In: Journal of Proteomics. 225, 103845.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-Range Distance Measurement by Transition Metal Ion FRET
Mortensen, Jonas Sigurd & Loland, Claus Juul, 2020, Biophysics of membrane proteins. Humana Press, p. 299-311 13 p. (Methods in Molecular Biology, Vol. 2168).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability
Slack, R. D., Ku, T. C., Cao, J., Giancola, J. L. B., Bonifazi, A., Loland, Claus Juul, Gadiano, A., Lam, J., Rais, R., Slusher, B. S., Coggiano, M., Tanda, G. & Newman, A. H., 2020, In: Journal of Medicinal Chemistry. 63, 5, p. 2343-2357 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter
Plenge, P., Abramyan, A. M., Sørensen, G., Mork, A., Weikop, Pia, Gether, Ulrik, Bang-Andersen, B., Shi, L. & Loland, Claus Juul, 2020, In: Nature Communications. 11, 1, 12 p., 1491.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release
Gotfryd, K., Boesen, T., Mortensen, Jonas Sigurd, Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In: Nature Communications. 11, 1, 14 p., 1005.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Conformational dynamics of the human serotonin transporter during substrate and drug binding
Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In: Nature Communications. 10, 1, 1687.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4359
Most downloads
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787
downloads
Grafted biomembranes containing membrane proteins – the case of the leucine transporter
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
209
downloads
Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
171
downloads
Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region
Research output: Contribution to journal › Journal article › Research › peer-review
Published