Claus Juul Løland
Professor
Neuropharm and Genetics
Blegdamsvej 3
2200 København N.
- 2024
- Published
Exploring the K+ binding site and its coupling to transport in the neurotransmitter: sodium symporter LeuT
Schmidt, S. G., Nygaard, Andreas, Mindell, J. A. & Loland, Claus Juul, 2024, In: eLife. 12, 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modifications to 1-(4-(2-Bis(4-fluorophenyl)methyl)sulfinyl)alkyl Alicyclic Amines That Improve Metabolic Stability and Retain an Atypical DAT Inhibitor Profile
Okorom, A. V., Camacho-Hernandez, G. A., Salomon, Kristine Walløe, Lee, K. H., Ku, T. C., Cao, J., Won, S. J., Friedman, J., Lam, J., Paule, J., Rais, R., Klein, B., Xi, Z. X., Shi, L., Loland, Claus Juul & Newman, A. H., 2024, In: Journal of Medicinal Chemistry. 67, 1, p. 709-727 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization
Yoon, S., Bae, H. E., Hariharan, P., Nygaard, Andreas, Lan, B., Woubshete, M., Sadaf, A., Liu, X., Loland, Claus Juul, Byrne, B., Guan, L. & Chae, P. S., 2024, In: Bioconjugate Chemistry. 35, 2, p. 223–231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Series of (([1,1′-Biphenyl]-2-yl)methyl)sulfinylalkyl Alicyclic Amines as Novel and High Affinity Atypical Dopamine Transporter Inhibitors with Reduced hERG Activity
Ku, T. C., Cao, J., Won, S. J., Guo, J., Camacho-Hernandez, G. A., Okorom, A. V., Salomon, Kristine Walløe, Lee, K. H., Loland, Claus Juul, Duff, H. J., Shi, L. & Newman, A. H., 2024, In: ACS Pharmacology and Translational Science. 7, 2, p. 515-532 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the human dopamine transporter in complex with cocaine
Nielsen, Jeppe Cederholm, Salomon, K., Kalenderoglou, I. E., Bargmeyer, S., Pape, Tillmann Hanns, Shahsavar, Azadeh & Loland, Claus Juul, 2024, In: Nature. 632, 8025, p. 678-685 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transmembrane transporter proteins: Capturing transport in motion
Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Transport and inhibition mechanisms of the human noradrenaline transporter
Hu, T., Yu, Z., Zhao, J., Meng, Y., Salomon, K., Bai, Q., Wei, Y., Zhang, J., Xu, S., Dai, Q., Yu, R., Yang, B., Loland, Claus Juul & Zhao, Y., 2024, In: Nature. 632, p. 930–937 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Dynamic extracellular vestibule of human SERT: Unveiling druggable potential with high-affinity allosteric inhibitors
Salomon, K., Abramyan, A. M., Plenge, P., Wang, L., Bundgaard, C., Bang-Andersen, B., Loland, Claus Juul & Shi, L., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 41, 10 p., e2304089120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance
Ghani, L., Kim, S., Ehsan, M., Lan, B., Poulsen, I. H., Dev, C., Katsube, S., Byrne, B., Guan, L., Loland, Claus Juul, Liu, X., Im, W. & Chae, P. S., 2023, In: Chemical Science. 14, 45, 11 p., 13014.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent binding at dopamine transporters determines sustained psychostimulant effects
Niello, M., Sideromenos, S., Gradisch, R., O'Shea, R., Schwazer, J., Maier, J., Kastner, N., Sandtner, W., Jäntsch, K., Lupica, C. R., Hoffman, A. F., Lubec, G., Loland, Claus Juul, Stockner, T., Pollak, D. D., Baumann, M. H. & Sitte, H. H., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 6, 11 p., e2114204120.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4359
Most downloads
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813
downloads
Grafted biomembranes containing membrane proteins – the case of the leucine transporter
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
234
downloads
Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
202
downloads
A Class of Rigid Linker-bearing Glucosides for Membrane Protein Structural Study
Research output: Contribution to journal › Journal article › Research › peer-review
Published