Jens D. Mikkelsen

Jens D. Mikkelsen

Professor


  1. 2014
  2. Published

    Photoperiodic Co-Regulation of Kisspeptin, Neurokinin B and Dynorphin in the Hypothalamus of a Seasonal Rodent

    Bartzen-Sprauer, J., Klosen, P., Ciofi, P., Mikkelsen, Jens D. & Simonneaux, V., Aug 2014, In: Journal of Neuroendocrinology. 26, 8, p. 510-520 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains

    Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, Gitte Moos, Aznar, S. & Mikkelsen, Jens D., 28 Mar 2014, In: Neuroscience. 263, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI

    Santini, M. A., Balu, D. T., Puhl, M. D., Hill-Smith, T. E., Berg, A. R., Lucki, I., Mikkelsen, Jens D. & Coyle, J. T., 1 Feb 2014, In: Behavioural Brain Research. 259, p. 242-246 5 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  5. Published

    Disparate Changes in Kisspeptin and Neurokinin B Expression in the Arcuate Nucleus After Sex Steroid Manipulation Reveal Differential Regulation of the Two KNDy Peptides in Rats

    Overgaard, A., Ruiz-Pino, F., Castellano, J. M., Tena-Sempere, M. & Mikkelsen, Jens D., 2014, In: Endocrinology. 155, 10, p. 3945-3955 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2013
  7. Published

    Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

    Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Reduced basal and novelty-induced levels of activity-regulated cytoskeleton associated protein (Arc) and c-Fos mRNA in the cerebral cortex and hippocampus of APPswe/PS1ΔE9 transgenic mice

    Christensen, D. Z., Thomsen, M. S. & Mikkelsen, Jens D., Jul 2013, In: Neurochemistry International. 63, 1, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearch

  9. Published

    Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy

    Klein, A. B., Jennum, Poul, Knudsen, S., Gammeltoft, S. & Mikkelsen, Jens D., 7 Jun 2013, In: Neuroscience Letters. 544, p. 31-35 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia

    Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice

    Overgaard, A., Tena-Sempere, M., Franceschini, I., Desroziers, E., Simonneaux, V. & Mikkelsen, Jens D., 2013, In: Peptides. 45, p. 85-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Distribution and seasonal variation in hypothalamic RF-amide peptides in a semi-desert rodent, the jerboa

    Janati, A., Talbi, R., Klosen, P., Mikkelsen, Jens D., Magoul, R., Simonneaux, V. & El Ouezzani, S., 2013, In: Journal of Neuroendocrinology. 25, 4, p. 402-411 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats

    Lie, M. E. K., Overgaard, A. & Mikkelsen, Jens D., 2013, In: Reproductive Biology. 13, 4, p. 298-308 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus)

    Piekarski, D. J., Zhao, S., Jennings, K. J., Iwasa, T., Legan, S. J., Mikkelsen, Jens D., Tsutsui, K. & Kriegsfeld, L. J., 2013, In: Hormones and Behavior. 64, 3, p. 501-510 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release

    Bortz, D. M., Mikkelsen, Jens D. & Bruno, J. P., 2013, In: Neuroscience. 255, p. 55-67

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Metabotropic glutamate receptor 2 and corticotrophin-releasing factor receptor-1 gene expression is differently regulated by BDNF in rat primary cortical neurons

    Jørgensen, C. V., Klein, A. B., El-Sayed, M., Knudsen, G. M. & Mikkelsen, Jens D., 2013, In: Synapse. 67, 11, p. 794-800

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Microduplication of 15q13.3 and Xq21.31 in a family with tourette syndrome and comorbidities

    Melchior, L., Bertelsen, B., Debes, Nanette M Monique Mol, Groth, C., Skov, L., Mikkelsen, Jens D., Brøndum-Nielsen, K. & Tümer, Asuman Zeynep, 2013, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 8, p. 825-831 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Tesofensine induces appetite suppression and weight loss with reversal of low forebrain dopamine levels in the diet-induced obese rat

    Hansen, H. H., Jensen, M. M., Overgaard, A., Weikop, Pia & Mikkelsen, Jens D., 2013, In: Pharmacology, Biochemistry and Behavior. 110, p. 265-271 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus

    Overgaard, A., Holst, K., Mandrup, K., Boberg, J., Christiansen, S., Jacobsen, A. P., Hass, U. & Mikkelsen, Jens D., 2013, In: NeuroToxicology. 37, p. 154-162 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex

    Menezes, M. M., Santini, M., Benvega, M. J., Marek, G. J., Merchant, K. M., Mikkelsen, Jens D. & Svensson, K. A., 2013, In: Neuroscience Journal. 2013, 8 p., 736439.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2012
  22. Published

    The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia

    Thomsen, M. S. & Mikkelsen, Jens D., 15 Oct 2012, In: Journal of Neuroimmunology. 251, 1-2, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearch

  23. Published

    Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist

    Brooks, J. M., Pershing, M. L., Thomsen, M. S., Mikkelsen, Jens D., Sarter, M. & Bruno, J. P., Oct 2012, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 37, 11, p. 2476-86 11 p.

    Research output: Contribution to journalJournal articleResearch

  24. Published

    Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors

    Thomsen, M. S. & Mikkelsen, Jens D., Oct 2012, In: Journal of Neurochemistry. 123, 1, p. 73-83 11 p.

    Research output: Contribution to journalJournal articleResearch

  25. Published

    The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?

    Thomsen, M. S. & Mikkelsen, Jens D., May 2012, In: Current Drug Targets. 13, 5, p. 707-20 14 p.

    Research output: Contribution to journalJournal articleResearch

  26. Published

    Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.

    Dyrvig, M., Hansen, H. H., Christiansen, S. H. O., Woldbye, David Paul Drucker, Mikkelsen, Jens D. & Lichota, J., 2012, In: Brain Research Bulletin. 88, p. 507-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Reprogrammering af modne celler til neuroner

    Mikkelsen, Jens D., Rasmussen, M. A., Meyer, M. & Knudsen, G. M., 2012, In: Ugeskrift for Laeger. 174, 12, p. 786

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2011
  29. Published

    Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats

    Thomsen, M. S., El-Sayed, M. & Mikkelsen, Jens D., 2011, In: PLOS ONE. 6, 11, p. e27014

    Research output: Contribution to journalJournal articleResearch

  30. Published

    Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder

    Thomsen, M. S., Weyn, A. & Mikkelsen, Jens D., 2011, In: Bipolar Disorders (English Edition, Online). 13, 7-8, p. 701-7 7 p.

    Research output: Contribution to journalJournal articleResearch

  31. 2010
  32. Published

    Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice

    Holm, P., Ettrup, A., Klein, A. B., Santini, M. A., El-Sayed, M., Elvang, A. B., Stensbøl, T. B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Kleijn, S. A., 1 Jan 2010, In: Journal of Alzheimer's Disease. 20, 4, p. 1201-13 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain

    Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Distinct neural pathways mediate α7 nicotinic acetylcholine receptor-dependent activation of the forebrain

    Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment

    Larsen, M. H., Mikkelsen, Jens D., Hay-Schmidt, Anders & Sandi, C., 2010, In: Journal of Psychiatric Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2009
  37. Published

    BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures

    Trajkovska, V., Santini, M. A., Marcussen, A. B., Thomsen, M. S., Hansen, H. H., Mikkelsen, Jens D., Arneberg, L., Kokaia, M., Knudsen, G. M. & Aznar, S., 2009, In: Neurochemistry International. 55, 7, p. 697-702 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus

    Bendová, Z., Sumová, A. & Mikkelsen, Jens D., 2009, In: Neuroscience. 159, 2, p. 599-609 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior

    Butini, S., Gemma, S., Campiani, G., Franceschini, S., Trotta, F., Borriello, M., Ceres, N., Ros, S., Coccone, S. S., Bernetti, M., De Angelis, M., Brindisi, M., Nacci, V., Fiorini, I., Novellino, E., Cagnotto, A., Mennini, T., Sandager-Nielsen, K., Andreasen, J. T., Scheel-Kruger, J. & 2 others, Mikkelsen, Jens D. & Fattorusso, C., 2009, In: Journal of Medicinal Chemistry. 52, 1, p. 151-69 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Melatonin controls seasonal breeding by a network of hypothalamic targets

    Revel, F. G., Masson-Pévet, M., Pévet, P., Mikkelsen, Jens D. & Simonneaux, V., 2009, In: Neuroendocrinology. 90, 1, p. 1-14 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice

    Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J. P., Mikkelsen, Jens D. & Mirza, N. R., 2009, In: Neuroscience. 163, 1, p. 73-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment

    Thomsen, M. S., Christensen, D. Z., Hansen, H. H., Redrobe, J. P. & Mikkelsen, Jens D., 2009, In: Neuropharmacology. 56, 6-7, p. 1001-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2008
  44. Published

    The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42

    Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, Jens D., 28 Aug 2008, In: Brain Research. 1227, p. 240-7 8 p.

    Research output: Contribution to journalJournal articleResearch

  45. Published

    The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat

    Thomsen, M. S., Mikkelsen, Jens D., Timmermann, D. B., Peters, D. A., Hay-Schmidt, Anders, Martens, H. A., Hansen, H. H. & Thomsen, M. S., 23 Jun 2008, In: Neuroscience. 154, 2, p. 741-53 13 p.

    Research output: Contribution to journalJournal articleResearch

  46. Published

    Kisspeptin and the seasonal control of reproduction in hamsters

    Simonneaux, V., Ansel, L., Revel, F. G., Klosen, P., Pévet, P. & Mikkelsen, Jens D., 2008, In: Peptides. 30, 1, p. 146-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats

    Bundzikova, J., Pirnik, Z., Zelena, D., Kiss, A. & Mikkelsen, Jens D., 2008, In: Cellular & Molecular Neurobiology. 28, 8, p. 1033-1047 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The neuroanatomy of the kisspeptin system in the mammalian brain

    Mikkelsen, Jens D. & Simonneaux, V., 2008, In: Peptides. 30, 1, p. 26-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2007
  50. Published

    The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat

    Kristensen, S., Thomsen, M. S., Hansen, H. H., Timmermann, D. B., Hay-Schmidt, Anders & Mikkelsen, Jens D., 17 May 2007, In: Neuroscience Letters. 418, 2, p. 154-8 5 p.

    Research output: Contribution to journalJournal articleResearch

  51. 2005
  52. Published

    Modulation of anxiety circuits by serotonergic systems

    Lowry, C. A., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D. & Shekhar, A., Dec 2005, In: Stress: The International Journal on the Biology of Stress . 8, 4, p. 233-246 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs

    Abrams, J. K., Johnson, P. L., Hay-Schmidt, Anders, Mikkelsen, Jens D., Shekhar, A. & Lowry, C. A., 2005, In: Neuroscience. 133, 4, p. 983-97 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2004
  55. Published

    Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis: interaction between 5-HT1A and 5-HT2A receptors

    Mikkelsen, Jens D., Hay-Schmidt, Anders & Kiss, A., Jun 2004, In: Annals of the New York Academy of Sciences. 1018, p. 65-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2001
  57. Published

    Hypocretin (orexin) in the rat pineal gland: A central transmitter with effects on noradrenaline-induced release of melatonin

    Mikkelsen, Jens D., Hauser, Frank, DeLecea, L., Sutcliffe, J. G., Kilduff, T. S., Calgari, C., Pévet, P. & Simonneaux, V., 2001, In: European Journal of Neuroscience. 14, 3, p. 419-425 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 1999
  59. Published

    Developmental expression of α-synuclein in rat hippocampus and cerebral cortex

    Petersen, K., Olesen, O. F. & Mikkelsen, Jens D., Jun 1999, In: Neuroscience. 91, 2, p. 651-659 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Neuropeptide Y (NPY) and NPY receptors in the rat pineal gland

    Mikkelsen, Jens D., Hauser, Frank & Olcese, J., 1999, In: Advances in Experimental Medicine and Biology. 460, p. 95-107 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 1998
  62. Published

    Amyloid β neurotoxicity in the cholinergic but not in the serotonergic phenotype of RN46A cells

    Olesen, O. F., Dagø, L. & Mikkelsen, Jens D., 15 Jun 1998, In: Molecular Brain Research. 57, 2, p. 266-274 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Aβ Induces Cell Death in Pc12 Cells and Tau-Transfected Cho Cells, but only Tau Phosphorylation in Pc12 Cells

    Fjord-Larsen, L., Mikkelsen, Jens D. & Olesen, O. F., 1998, Progress in Alzheimer’s and Parkinson’s Diseases . p. 257-263 7 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

ID: 32177473