Jens D. Mikkelsen

Jens D. Mikkelsen

Professor

ORCID: 0000-0002-0498-6861

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  1. Published

    5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains

    Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, Gitte Moos, Aznar, S. & Mikkelsen, Jens D., 28 Mar 2014, In: Neuroscience. 263, p. 36-45 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Acute phencyclidine administration induces c-Fos-immunoreactivity in interneurons in cortical and subcortical regions

    Hervig, M. E., Thomsen, M. S., Kalló, I. & Mikkelsen, Jens D., 15 Oct 2016, In: Neuroscience. 334, p. 13-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons

    Larsen, H. M., Hansen, S. K., Mikkelsen, Jens D., Hyttel, P. & Stummann, T. C., 2019, In: Stem Cell Research. 41, 10 p., 101642.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Amyloid β neurotoxicity in the cholinergic but not in the serotonergic phenotype of RN46A cells

    Olesen, O. F., Dagø, L. & Mikkelsen, Jens D., 15 Jun 1998, In: Molecular Brain Research. 57, 2, p. 266-274 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Analysis of gonadotrophin-releasing hormone-1 and kisspeptin neuronal systems in the nonphotoregulated seasonally breeding eastern rock elephant-shrew (Elephantulus myurus)

    Medger, K., Bennett, N. C., Chimimba, C. T., Oosthuizen, M. K., Mikkelsen, Jens D. & Coen, C. W., 2018, In: The Journal of Comparative Neurology. 526, 15, p. 2388-2405

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Anti-Inflammatory Effect of Alpha7 Nicotinic Acetylcholine Receptor Modulators on BV2 Cells

    trj450, trj450 & Mikkelsen, Jens D., 2022, In: Neuroimmunomodulation. 27, 4, p. 194-202 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study

    Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Association of the CHRNA7 promoter variant −86T with Tourette syndrome and comorbid obsessive-compulsive disorder

    Bertelsen, B., Melchior, L., Tümer, Asuman Zeynep, Groth, C., Mol Debes, N., Skov, L., Holst, K. K., Fagerlund, Birgitte & Mikkelsen, Jens D., 30 Nov 2014, In: Psychiatry Research. 219, 3, p. 710-711 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  9. Published

    Aβ Induces Cell Death in Pc12 Cells and Tau-Transfected Cho Cells, but only Tau Phosphorylation in Pc12 Cells

    Fjord-Larsen, L., Mikkelsen, Jens D. & Olesen, O. F., 1998, Progress in Alzheimer’s and Parkinson’s Diseases . p. 257-263 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels

    Fisher, Patrick Mac Donald, Holst, K. K., Adamsen, D., Klein, A. B., Frøkjær, Vibe Gedsø, Jensen, P. S., Svarer, C., Gillings, N., Baare, W. F. C., Mikkelsen, Jens D. & Knudsen, G. M., Jan 2015, In: Human Brain Mapping. 36, 1, p. 313–323 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures

    Trajkovska, V., Santini, M. A., Marcussen, A. B., Thomsen, M. S., Hansen, H. H., Mikkelsen, Jens D., Arneberg, L., Kokaia, M., Knudsen, G. M. & Aznar, S., 2009, In: Neurochemistry International. 55, 7, p. 697-702 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

    Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Changes in Binding of [123I]CLINDE, a High-Affinity Translocator Protein 18 kDa (TSPO) Selective Radioligand in a Rat Model of Traumatic Brain Injury

    Donat, C. K., Gaber, K., Meixensberger, J., Brust, P., Pinborg, Lars Hageman, Hansen, H. H. & Mikkelsen, Jens D., Jun 2016, In: NeuroMolecular Medicine. 18, 2, p. 158-69 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Changes in RFamide-Related Peptide-1 (RFRP-1)-Immunoreactivity During Postnatal Development and the Estrous Cycle

    Jørgensen, S. R., Andersen, M. D., Overgaard, A. & Mikkelsen, Jens D., Nov 2014, In: Endocrinology. 155, 11, p. 4402-4410 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease

    Hansen, H. H., Fabricius, K., Barkholt, P., Mikkelsen, Jens D., Jelsing, J., Pyke, C., Knudsen, L. B. & Vrang, N., 1 Sep 2016, In: Brain Research. 1646, p. 354-365 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus

    Bendová, Z., Sumová, A. & Mikkelsen, Jens D., 2009, In: Neuroscience. 159, 2, p. 599-609 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice

    Overgaard, A., Tena-Sempere, M., Franceschini, I., Desroziers, E., Simonneaux, V. & Mikkelsen, Jens D., 2013, In: Peptides. 45, p. 85-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI

    Santini, M. A., Balu, D. T., Puhl, M. D., Hill-Smith, T. E., Berg, A. R., Lucki, I., Mikkelsen, Jens D. & Coyle, J. T., 1 Feb 2014, In: Behavioural Brain Research. 259, p. 242-246 5 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  19. Published

    DNA methylation regulates CHRNA7 transcription and can be modulated by valproate

    Dyrvig, M., Mikkelsen, Jens D. & Lichota, J., Jun 2019, In: Neuroscience Letters. 704, p. 145-152

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Developmental expression of α-synuclein in rat hippocampus and cerebral cortex

    Petersen, K., Olesen, O. F. & Mikkelsen, Jens D., Jun 1999, In: Neuroscience. 91, 2, p. 651-659 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats

    Thomsen, M. S., El-Sayed, M. & Mikkelsen, Jens D., 2011, In: PLOS ONE. 6, 11, p. e27014

    Research output: Contribution to journal › Journal article › Research

  22. Published

    Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior

    Butini, S., Gemma, S., Campiani, G., Franceschini, S., Trotta, F., Borriello, M., Ceres, N., Ros, S., Coccone, S. S., Bernetti, M., De Angelis, M., Brindisi, M., Nacci, V., Fiorini, I., Novellino, E., Cagnotto, A., Mennini, T., Sandager-Nielsen, K., Andreasen, J. T., Scheel-Kruger, J. & 2 others, Mikkelsen, Jens D. & Fattorusso, C., 2009, In: Journal of Medicinal Chemistry. 52, 1, p. 151-69 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Disparate Changes in Kisspeptin and Neurokinin B Expression in the Arcuate Nucleus After Sex Steroid Manipulation Reveal Differential Regulation of the Two KNDy Peptides in Rats

    Overgaard, A., Ruiz-Pino, F., Castellano, J. M., Tena-Sempere, M. & Mikkelsen, Jens D., 2014, In: Endocrinology. 155, 10, p. 3945-3955 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain

    Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Distinct neural pathways mediate α7 nicotinic acetylcholine receptor-dependent activation of the forebrain

    Thomsen, M. S., Hay-Schmidt, Anders, Hansen, H. H. & Mikkelsen, Jens D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Distribution and seasonal variation in hypothalamic RF-amide peptides in a semi-desert rodent, the jerboa

    Janati, A., Talbi, R., Klosen, P., Mikkelsen, Jens D., Magoul, R., Simonneaux, V. & El Ouezzani, S., 2013, In: Journal of Neuroendocrinology. 25, 4, p. 402-411 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effect of a postnatal high-fat diet exposure on puberty onset, estrous cycle regularity, and kisspeptin expression in female rats

    Lie, M. E. K., Overgaard, A. & Mikkelsen, Jens D., 2013, In: Reproductive Biology. 13, 4, p. 298-308 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Efferent connections from the lateral hypothalamic region and the lateral preoptic area to the hypothalamic paraventricular nucleus of the rat

    Larsen, P. J., Hay-Schmidt, Anders & Mikkelsen, Jens D., 1994, In: Journal of Comparative Neurology. 342, 2, p. 299-319 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Encenicline, an α7 Nicotinic Acetylcholine Receptor Partial Agonist, Reduces Immune Cell Infiltration in the Colon and Improves Experimental Colitis in Mice

    Salaga, M., Blomster, L. V., Piechota-Polańczyk, A., Zielińska, M., Jacenik, D., Cygankiewicz, A. I., Krajewska, W. M., Mikkelsen, Jens D. & Fichna, J., Jan 2016, In: Journal of Pharmacology and Experimental Therapeutics. 356, 1, p. 157-69 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia

    Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.

    Dyrvig, M., Hansen, H. H., Christiansen, S. H. O., Woldbye, David Paul Drucker, Mikkelsen, Jens D. & Lichota, J., 2012, In: Brain Research Bulletin. 88, p. 507-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Expression of the Ly-6 family proteins Lynx1 and Ly6H in the rat brain is compartmentalized, cell-type specific, and developmentally regulated

    Thomsen, M. S., Cinar, B., Jensen, M. M., Lyukmanova, E. N., Shulepko, M. A., Tsetlin, V., Klein, A. B. & Mikkelsen, Jens D., 17 Nov 2014, In: Brain Structure and Function (Print Edition). 219, 6, p. 1923-1934 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)

    Pazarlar, B. A., trj450, trj450, Petukhov, V., Pinborg, Lars Hageman, Khodosevich, Konstantin & Mikkelsen, Jens D., 2022, In: Molecular Brain. 15, 1, 45.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Functional interaction between Lypd6 and nicotinic acetylcholine receptors

    Arvaniti, M., Jensen, M. M., Soni, N., Wang, H., Klein, A. B., Thiriet, N., Pinborg, Lars Hageman, Muldoon, P. P., Wienecke, Jacob, Imad Damaj, M., Kohlmeier, Kristi Anne, Gondré-Lewis, M. C., Mikkelsen, Jens D. & Thomsen, M. S., Sep 2016, In: Journal of Neurochemistry. 138, 6, p. 806-820 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Gonadotropin-inhibitory hormone reduces sexual motivation but not lordosis behavior in female Syrian hamsters (Mesocricetus auratus)

    Piekarski, D. J., Zhao, S., Jennings, K. J., Iwasa, T., Legan, S. J., Mikkelsen, Jens D., Tsutsui, K. & Kriegsfeld, L. J., 2013, In: Hormones and Behavior. 64, 3, p. 501-510 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain

    Wu, J., Liu, Q., Tang, P., Mikkelsen, Jens D., Shen, J., Whiteaker, P. & Yakel, J. L., Jul 2016, In: Trends in Pharmacological Sciences. 37, 7, p. 562-74 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    High plasma triglyceride levels strongly correlate with low kisspeptin in the arcuate nucleus of male rats

    Overgaard, A., Axel, A. M., Lie, M. E., Hansen, H. H. & Mikkelsen, Jens D., Apr 2015, In: Endocrine Regulations. 49, 2, p. 51-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder

    Thomsen, M. S., Weyn, A. & Mikkelsen, Jens D., 2011, In: Bipolar Disorders (English Edition, Online). 13, 7-8, p. 701-7 7 p.

    Research output: Contribution to journal › Journal article › Research

  39. Published

    Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor

    Lyukmanova, E. N., Shulepko, M. A., Kudryavtsev, D., Bychkov, M. L., Kulbatskii, D. S., Kasheverov, I. E., Astapova, M. V., Feofanov, A. V., Thomsen, M. S., Mikkelsen, Jens D., Shenkarev, Z. O., Tsetlin, V. I., Dolgikh, D. A. & Kirpichnikov, M. P., 2016, In: PLOS ONE. 11, 2, p. 1-14 14 p., e0149733.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Hypocretin (orexin) in the rat pineal gland: A central transmitter with effects on noradrenaline-induced release of melatonin

    Mikkelsen, Jens D., Hauser, Frank, DeLecea, L., Sutcliffe, J. G., Kilduff, T. S., Calgari, C., Pévet, P. & Simonneaux, V., 2001, In: European Journal of Neuroscience. 14, 3, p. 419-425 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis: [incl. Author Correction]

    Pfisterer, U., Petukhov, V., Demharter, S., Meichsner, J., Thompson, J. J., Batiuk, M. Y., Martinez, A. A., Vasistha, Navneet A, Thakur, A., Mikkelsen, Jens D., Adorjan, I., Pinborg, Lars Hageman, Pers, Tune H, von Engelhardt, J., Kharchenko, P. V. & Khodosevich, K., 2020, In: Nature Communications. 11, 1, 19 p., 5038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Immunohistochemical localisation and developmental aspects of epidermal growth factor in the rat

    Raaberg, L., Nexo, E., Mikkelsen, Jens D. & Poulsen, Steen Seier, 1 Jul 1988, In: Histochemistry. 89, 4, p. 351-356 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    In vitro and in vivo characterization of dibenzothiophene derivatives [125I]iodo-ASEM and [18F]ASEM as radiotracers of homo- And heteromeric α7 nicotinic acetylcholine receptors

    Donat, C. K., Hansen, H. H., Hansen, H. D., Mease, R. C., Horti, A. G., Pomper, M. G., L’Estrade, E. T., Herth, Matthias Manfred, Peters, D., Knudsen, Gitte Moos & Mikkelsen, Jens D., 1 Jan 2020, In: Molecules. 25, 6, 19 p., 1425.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Increased serum brain-derived neurotrophic factor (BDNF) levels in patients with narcolepsy

    Klein, A. B., Jennum, Poul, Knudsen, S., Gammeltoft, S. & Mikkelsen, Jens D., 7 Jun 2013, In: Neuroscience Letters. 544, p. 31-35 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Induced resistance in sugar beet against Cercospora beticola: Induction by dichloroisonicotinic acid is independent of chitinase and β-1,3-glucanase transcript accumulation

    Nielsen, K. K., Bojsen, K., Collinge, David B. & Mikkelsen, Jens D., 1 Jan 1994, In: Physiological and Molecular Plant Pathology. 45, 2, p. 89-99 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi

    Vad, K., Mikkelsen, Jens D. & Collinge, David B., 1 Apr 1991, In: Planta. 184, 1, p. 24-29 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Isoform-specific binding of human apolipoprotein E to the non-amyloid β component of Alzheimer's disease amyloid

    Olesen, O. F., Mikkelsen, Jens D., Gerdes, C. & Jensen, P. H., Feb 1997, In: Molecular Brain Research. 44, 1, p. 105-112 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Kisspeptin and the seasonal control of reproduction in hamsters

    Simonneaux, V., Ansel, L., Revel, F. G., Klosen, P., Pévet, P. & Mikkelsen, Jens D., 2008, In: Peptides. 30, 1, p. 146-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Localized infusions of the partial alpha 7 nicotinic receptor agonist SSR180711 evoke rapid and transient increases in prefrontal glutamate release

    Bortz, D. M., Mikkelsen, Jens D. & Bruno, J. P., 2013, In: Neuroscience. 255, p. 55-67

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

    Runegaard, A. H., Sørensen, Andreas Toft, Fitzpatrick, C. M., Jørgensen, Søren Heide, Petersen, A. V., Hansen, Nikolaj Winther, Weikop, Pia, Andreasen T., Jesper, Mikkelsen, Jens D., Perrier, Jean-Francois Marie, Woldbye, David Paul Drucker, Rickhag, Karl Mattias, Wörtwein, Gitta & Gether, Ulrik, 2018, In: eNeuro. 5, 3, 26 p., e0345.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 32177473